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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMFR
Full Name:
Autocrine motility factor receptor, isoform 2
Alias:
AMFR1; autocrine motility factor receptor; GP78; RNF45
Type:
EC 6.3.2.-; Ligase; EC 6.3.2.19; Receptor, misc.; Ubiquitin conjugating system; Membrane protein, integral; Motility/polarity/chemotaxis; Ubiquitin ligase; Endoplasmic reticulum
Mass (Da):
73000
Number AA:
UniProt ID:
Q9UKV5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030176
GO:0000299
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004872
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0030433
GO:0030968
GO:0051259
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
L
E
R
F
P
W
P
S
L
R
T
Y
T
G
L
Site 2
Y17
P
W
P
S
L
R
T
Y
T
G
L
S
G
L
A
Site 3
S37
I
S
A
Y
R
A
L
S
Q
P
E
A
G
P
G
Site 4
T50
P
G
E
P
D
Q
L
T
A
S
L
Q
P
E
P
Site 5
S52
E
P
D
Q
L
T
A
S
L
Q
P
E
P
P
A
Site 6
S64
P
P
A
P
A
R
P
S
A
G
G
P
R
A
R
Site 7
Y76
R
A
R
D
V
A
Q
Y
L
L
S
D
S
L
F
Site 8
S113
V
F
G
P
L
R
V
S
E
R
Q
H
L
K
D
Site 9
Y171
L
C
K
D
R
F
E
Y
L
S
F
S
P
T
T
Site 10
S173
K
D
R
F
E
Y
L
S
F
S
P
T
T
P
M
Site 11
S175
R
F
E
Y
L
S
F
S
P
T
T
P
M
S
S
Site 12
T177
E
Y
L
S
F
S
P
T
T
P
M
S
S
H
G
Site 13
T178
Y
L
S
F
S
P
T
T
P
M
S
S
H
G
R
Site 14
S181
F
S
P
T
T
P
M
S
S
H
G
R
V
L
S
Site 15
S182
S
P
T
T
P
M
S
S
H
G
R
V
L
S
L
Site 16
Y256
T
W
E
G
K
G
T
Y
V
Y
Y
T
D
F
V
Site 17
Y258
E
G
K
G
T
Y
V
Y
Y
T
D
F
V
M
E
Site 18
Y259
G
K
G
T
Y
V
Y
Y
T
D
F
V
M
E
L
Site 19
Y315
R
I
R
R
H
K
N
Y
L
R
V
V
G
N
M
Site 20
S367
F
H
N
S
C
L
R
S
W
L
E
Q
D
T
S
Site 21
T377
E
Q
D
T
S
C
P
T
C
R
M
S
L
N
I
Site 22
S455
G
I
T
Q
A
S
N
S
Q
L
N
A
M
A
H
Site 23
S485
Q
D
L
Q
L
T
R
S
V
E
I
T
T
D
N
Site 24
T489
L
T
R
S
V
E
I
T
T
D
N
I
L
E
G
Site 25
T504
R
I
Q
V
P
F
P
T
Q
R
S
D
S
I
R
Site 26
S507
V
P
F
P
T
Q
R
S
D
S
I
R
P
A
L
Site 27
S509
F
P
T
Q
R
S
D
S
I
R
P
A
L
N
S
Site 28
S516
S
I
R
P
A
L
N
S
P
V
E
R
P
S
S
Site 29
S522
N
S
P
V
E
R
P
S
S
D
Q
E
E
G
E
Site 30
S523
S
P
V
E
R
P
S
S
D
Q
E
E
G
E
T
Site 31
T530
S
D
Q
E
E
G
E
T
S
A
Q
T
E
R
V
Site 32
S531
D
Q
E
E
G
E
T
S
A
Q
T
E
R
V
P
Site 33
T534
E
G
E
T
S
A
Q
T
E
R
V
P
L
D
L
Site 34
S542
E
R
V
P
L
D
L
S
P
R
L
E
E
T
L
Site 35
S559
G
E
V
E
V
E
P
S
E
V
E
D
F
E
A
Site 36
S569
E
D
F
E
A
R
G
S
R
F
S
K
S
A
D
Site 37
S572
E
A
R
G
S
R
F
S
K
S
A
D
E
R
Q
Site 38
S574
R
G
S
R
F
S
K
S
A
D
E
R
Q
R
M
Site 39
S601
R
K
R
F
L
N
K
S
S
E
D
D
A
A
S
Site 40
S602
K
R
F
L
N
K
S
S
E
D
D
A
A
S
E
Site 41
S608
S
S
E
D
D
A
A
S
E
S
F
L
P
S
E
Site 42
S610
E
D
D
A
A
S
E
S
F
L
P
S
E
G
A
Site 43
S614
A
S
E
S
F
L
P
S
E
G
A
S
S
D
P
Site 44
S618
F
L
P
S
E
G
A
S
S
D
P
V
T
L
R
Site 45
S619
L
P
S
E
G
A
S
S
D
P
V
T
L
R
R
Site 46
T623
G
A
S
S
D
P
V
T
L
R
R
R
M
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation