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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXL21
Full Name:
Alias:
Type:
Mass (Da):
49152
Number AA:
434
UniProt ID:
Q9UKT6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
K
R
N
S
L
S
V
E
N
K
I
V
Q
Site 2
S29
P
K
V
G
F
Y
S
S
L
N
Q
T
H
T
H
Site 3
T33
F
Y
S
S
L
N
Q
T
H
T
H
T
V
L
L
Site 4
T35
S
S
L
N
Q
T
H
T
H
T
V
L
L
D
W
Site 5
T37
L
N
Q
T
H
T
H
T
V
L
L
D
W
G
S
Site 6
S92
F
E
F
E
L
N
Q
S
A
T
S
S
F
K
S
Site 7
T94
F
E
L
N
Q
S
A
T
S
S
F
K
S
T
H
Site 8
S95
E
L
N
Q
S
A
T
S
S
F
K
S
T
H
P
Site 9
S96
L
N
Q
S
A
T
S
S
F
K
S
T
H
P
D
Site 10
S99
S
A
T
S
S
F
K
S
T
H
P
D
L
I
Q
Site 11
T100
A
T
S
S
F
K
S
T
H
P
D
L
I
Q
Q
Site 12
Y118
K
H
F
A
H
L
Q
Y
V
S
F
K
V
D
S
Site 13
S125
Y
V
S
F
K
V
D
S
S
A
E
S
A
E
A
Site 14
S126
V
S
F
K
V
D
S
S
A
E
S
A
E
A
A
Site 15
S129
K
V
D
S
S
A
E
S
A
E
A
A
C
D
I
Site 16
S157
L
I
S
T
A
K
P
S
F
M
N
V
S
E
S
Site 17
S162
K
P
S
F
M
N
V
S
E
S
H
F
V
S
A
Site 18
S181
F
I
N
S
K
S
L
S
S
I
K
I
E
D
T
Site 19
T188
S
S
I
K
I
E
D
T
P
V
D
D
P
S
L
Site 20
S194
D
T
P
V
D
D
P
S
L
K
I
L
V
A
N
Site 21
S203
K
I
L
V
A
N
N
S
D
T
L
R
L
P
K
Site 22
T205
L
V
A
N
N
S
D
T
L
R
L
P
K
M
S
Site 23
S212
T
L
R
L
P
K
M
S
S
C
P
H
V
S
S
Site 24
S213
L
R
L
P
K
M
S
S
C
P
H
V
S
S
D
Site 25
S267
H
L
R
I
D
V
V
S
E
N
P
G
Q
I
K
Site 26
T308
L
Y
E
E
E
F
E
T
F
F
K
E
E
T
P
Site 27
T314
E
T
F
F
K
E
E
T
P
V
T
H
L
Y
F
Site 28
T317
F
K
E
E
T
P
V
T
H
L
Y
F
G
R
S
Site 29
Y320
E
T
P
V
T
H
L
Y
F
G
R
S
V
S
K
Site 30
T394
R
L
C
E
R
R
L
T
Q
L
S
V
M
E
E
Site 31
Y409
V
L
I
P
D
E
D
Y
S
L
D
E
I
H
T
Site 32
S410
L
I
P
D
E
D
Y
S
L
D
E
I
H
T
E
Site 33
Y421
I
H
T
E
V
S
K
Y
L
G
R
V
W
F
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation