KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GTF3C4
Full Name:
General transcription factor 3C polypeptide 4
Alias:
General transcription factor IIIC, polypeptide 4, 90kDa; KAT12; TF3C4; TFIIIC90; Transcription factor IIIC subunit delta; Transcription factor IIIC90
Type:
EC 2.3.1.48; Acetyltransferase
Mass (Da):
91982
Number AA:
822
UniProt ID:
Q9UKN8
International Prot ID:
IPI00016725
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000127
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008047
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0042791
GO:0042797
GO:0006384
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
A
D
D
G
P
A
P
S
G
E
E
E
G
E
G
Site 2
Y62
E
P
A
V
K
L
Q
Y
A
V
S
G
L
E
P
Site 3
S79
W
S
E
D
H
R
V
S
V
S
T
A
R
S
I
Site 4
S81
E
D
H
R
V
S
V
S
T
A
R
S
I
A
V
Site 5
T107
Q
D
L
V
I
H
R
T
S
V
P
A
P
L
N
Site 6
S108
D
L
V
I
H
R
T
S
V
P
A
P
L
N
S
Site 7
S142
A
S
K
D
P
T
V
S
Q
T
F
M
L
D
R
Site 8
T144
K
D
P
T
V
S
Q
T
F
M
L
D
R
V
F
Site 9
Y166
P
P
M
R
G
F
K
Y
T
S
W
S
P
M
G
Site 10
T192
L
T
M
D
N
R
L
T
I
Q
A
N
L
N
R
Site 11
Y217
E
I
Y
G
E
R
L
Y
E
T
S
Y
R
L
S
Site 12
T219
Y
G
E
R
L
Y
E
T
S
Y
R
L
S
K
N
Site 13
S220
G
E
R
L
Y
E
T
S
Y
R
L
S
K
N
E
Site 14
S224
Y
E
T
S
Y
R
L
S
K
N
E
A
P
E
G
Site 15
S244
A
E
F
Q
R
R
H
S
M
Q
T
P
V
R
M
Site 16
T247
Q
R
R
H
S
M
Q
T
P
V
R
M
E
W
S
Site 17
S301
F
V
G
K
E
S
I
S
S
C
N
T
I
E
S
Site 18
S302
V
G
K
E
S
I
S
S
C
N
T
I
E
S
G
Site 19
T305
E
S
I
S
S
C
N
T
I
E
S
G
I
T
S
Site 20
S308
S
S
C
N
T
I
E
S
G
I
T
S
P
S
V
Site 21
S329
E
H
N
N
R
K
M
S
G
L
I
V
G
S
A
Site 22
Y380
S
I
K
C
V
P
L
Y
H
P
Y
Q
K
C
S
Site 23
Y383
C
V
P
L
Y
H
P
Y
Q
K
C
S
C
S
L
Site 24
Y398
V
V
A
A
R
G
S
Y
V
F
W
R
L
L
L
Site 25
S416
A
G
L
N
V
H
N
S
H
V
T
G
L
H
S
Site 26
T437
T
A
D
K
Q
N
G
T
V
Y
T
C
S
S
D
Site 27
Y439
D
K
Q
N
G
T
V
Y
T
C
S
S
D
G
K
Site 28
S442
N
G
T
V
Y
T
C
S
S
D
G
K
V
R
Q
Site 29
S469
E
H
Q
L
I
K
L
S
D
V
F
G
S
V
R
Site 30
Y508
L
H
P
V
N
K
N
Y
Q
V
Q
F
V
T
L
Site 31
T571
K
I
E
S
S
G
V
T
Y
F
W
R
F
K
L
Site 32
S587
L
L
R
I
L
Y
Q
S
M
Q
K
T
P
S
E
Site 33
T591
L
Y
Q
S
M
Q
K
T
P
S
E
A
L
W
K
Site 34
T600
S
E
A
L
W
K
P
T
H
E
D
S
K
I
L
Site 35
S604
W
K
P
T
H
E
D
S
K
I
L
L
V
D
S
Site 36
S611
S
K
I
L
L
V
D
S
P
G
M
G
N
A
D
Site 37
S628
Q
Q
E
E
G
T
S
S
K
Q
V
V
K
Q
G
Site 38
T649
E
G
D
V
E
E
P
T
D
D
S
L
P
T
T
Site 39
S652
V
E
E
P
T
D
D
S
L
P
T
T
G
D
A
Site 40
T656
T
D
D
S
L
P
T
T
G
D
A
G
G
R
E
Site 41
T684
E
A
V
E
M
H
L
T
R
E
H
M
K
R
V
Site 42
S718
G
L
C
N
F
L
M
S
D
E
E
Y
D
D
R
Site 43
Y722
F
L
M
S
D
E
E
Y
D
D
R
T
A
R
V
Site 44
T726
D
E
E
Y
D
D
R
T
A
R
V
L
I
G
H
Site 45
S735
R
V
L
I
G
H
I
S
K
K
M
N
K
Q
T
Site 46
T742
S
K
K
M
N
K
Q
T
F
P
E
H
C
S
L
Site 47
S748
Q
T
F
P
E
H
C
S
L
C
K
E
I
L
P
Site 48
T757
C
K
E
I
L
P
F
T
D
R
K
Q
A
V
C
Site 49
Y785
Q
S
C
Q
S
L
I
Y
R
R
C
L
L
H
D
Site 50
S793
R
R
C
L
L
H
D
S
I
A
R
H
P
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation