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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBW1B
Full Name:
F-box/WD repeat-containing protein 11
Alias:
BTRC2; BTRCP2; F-box and WD repeat domain containing 11; F-box and WD- repeats protein beta-TrCP2; F-box/WD-repeat protein 11; F-box/WD-repeat protein 1B; Fbw11; Fbw1b; FBXW11; FBXW1B; Hos; KIAA0696
Type:
Ubiquitin conjugating system
Mass (Da):
62091
Number AA:
542
UniProt ID:
Q9UKB1
International Prot ID:
IPI00328796
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0000151
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0019941
GO:0016567
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S55
L
Q
I
S
N
G
T
S
S
V
I
V
S
R
K
Site 2
S56
Q
I
S
N
G
T
S
S
V
I
V
S
R
K
R
Site 3
S60
G
T
S
S
V
I
V
S
R
K
R
P
S
E
G
Site 4
S65
I
V
S
R
K
R
P
S
E
G
N
Y
Q
K
E
Site 5
Y69
K
R
P
S
E
G
N
Y
Q
K
E
K
D
L
C
Site 6
Y79
E
K
D
L
C
I
K
Y
F
D
Q
W
S
E
S
Site 7
Y110
Q
H
G
H
I
N
S
Y
L
K
P
M
L
Q
R
Site 8
S182
D
P
L
W
K
G
L
S
E
R
R
G
W
D
Q
Site 9
Y190
E
R
R
G
W
D
Q
Y
L
F
K
N
R
P
T
Site 10
T197
Y
L
F
K
N
R
P
T
D
G
P
P
N
S
F
Site 11
S203
P
T
D
G
P
P
N
S
F
Y
R
S
L
Y
P
Site 12
Y205
D
G
P
P
N
S
F
Y
R
S
L
Y
P
K
I
Site 13
S207
P
P
N
S
F
Y
R
S
L
Y
P
K
I
I
Q
Site 14
Y209
N
S
F
Y
R
S
L
Y
P
K
I
I
Q
D
I
Site 15
T218
K
I
I
Q
D
I
E
T
I
E
S
N
W
R
C
Site 16
S237
L
Q
R
I
Q
C
R
S
E
N
S
K
G
V
Y
Site 17
Y244
S
E
N
S
K
G
V
Y
C
L
Q
Y
D
D
E
Site 18
Y248
K
G
V
Y
C
L
Q
Y
D
D
E
K
I
I
S
Site 19
S255
Y
D
D
E
K
I
I
S
G
L
R
D
N
S
I
Site 20
S261
I
S
G
L
R
D
N
S
I
K
I
W
D
K
T
Site 21
T268
S
I
K
I
W
D
K
T
S
L
E
C
L
K
V
Site 22
T301
V
T
G
S
S
D
S
T
V
R
V
W
D
V
N
Site 23
T315
N
T
G
E
V
L
N
T
L
I
H
H
N
E
A
Site 24
Y375
V
V
D
F
D
D
K
Y
I
V
S
A
S
G
D
Site 25
S380
D
K
Y
I
V
S
A
S
G
D
R
T
I
K
V
Site 26
T384
V
S
A
S
G
D
R
T
I
K
V
W
S
T
S
Site 27
T398
S
T
C
E
F
V
R
T
L
N
G
H
K
R
G
Site 28
Y411
R
G
I
A
C
L
Q
Y
R
D
R
L
V
V
S
Site 29
S418
Y
R
D
R
L
V
V
S
G
S
S
D
N
T
I
Site 30
S420
D
R
L
V
V
S
G
S
S
D
N
T
I
R
L
Site 31
T424
V
S
G
S
S
D
N
T
I
R
L
W
D
I
E
Site 32
S458
F
D
N
K
R
I
V
S
G
A
Y
D
G
K
I
Site 33
S492
L
R
T
L
V
E
H
S
G
R
V
F
R
L
Q
Site 34
S525
D
F
L
N
V
P
P
S
A
Q
N
E
T
R
S
Site 35
T530
P
P
S
A
Q
N
E
T
R
S
P
S
R
T
Y
Site 36
S532
S
A
Q
N
E
T
R
S
P
S
R
T
Y
T
Y
Site 37
S534
Q
N
E
T
R
S
P
S
R
T
Y
T
Y
I
S
Site 38
T536
E
T
R
S
P
S
R
T
Y
T
Y
I
S
R
_
Site 39
Y537
T
R
S
P
S
R
T
Y
T
Y
I
S
R
_
_
Site 40
T538
R
S
P
S
R
T
Y
T
Y
I
S
R
_
_
_
Site 41
Y539
S
P
S
R
T
Y
T
Y
I
S
R
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation