KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FBXO10
Full Name:
Alias:
Type:
Mass (Da):
105195
Number AA:
956
UniProt ID:
Q9UK96
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
A
W
Y
E
L
I
L
S
L
D
S
T
R
W
R
Site 2
S42
E
L
I
L
S
L
D
S
T
R
W
R
Q
L
C
Site 3
S70
Q
P
D
V
E
P
E
S
W
R
E
A
F
K
Q
Site 4
Y79
R
E
A
F
K
Q
H
Y
L
A
S
K
T
W
T
Site 5
S94
K
N
A
L
D
L
E
S
S
I
C
F
S
L
F
Site 6
S99
L
E
S
S
I
C
F
S
L
F
R
R
R
R
E
Site 7
T109
R
R
R
R
E
R
R
T
L
S
V
G
P
G
R
Site 8
S111
R
R
E
R
R
T
L
S
V
G
P
G
R
E
F
Site 9
S120
G
P
G
R
E
F
D
S
L
G
S
A
L
A
M
Site 10
Y194
A
W
F
S
P
I
M
Y
K
T
T
S
G
H
V
Site 11
T196
F
S
P
I
M
Y
K
T
T
S
G
H
V
Q
F
Site 12
S251
E
N
C
E
F
V
G
S
E
N
N
S
V
T
V
Site 13
S255
F
V
G
S
E
N
N
S
V
T
V
E
G
H
P
Site 14
T257
G
S
E
N
N
S
V
T
V
E
G
H
P
S
A
Site 15
Y270
S
A
D
K
N
W
A
Y
K
Y
L
L
G
L
I
Site 16
Y272
D
K
N
W
A
Y
K
Y
L
L
G
L
I
K
S
Site 17
T282
G
L
I
K
S
S
P
T
F
L
P
T
E
D
S
Site 18
T286
S
S
P
T
F
L
P
T
E
D
S
D
F
L
M
Site 19
S289
T
F
L
P
T
E
D
S
D
F
L
M
S
L
D
Site 20
S294
E
D
S
D
F
L
M
S
L
D
L
E
S
R
D
Site 21
S305
E
S
R
D
Q
A
W
S
P
K
T
C
D
I
V
Site 22
T308
D
Q
A
W
S
P
K
T
C
D
I
V
I
E
G
Site 23
S316
C
D
I
V
I
E
G
S
Q
S
P
T
S
P
A
Site 24
S318
I
V
I
E
G
S
Q
S
P
T
S
P
A
S
S
Site 25
T320
I
E
G
S
Q
S
P
T
S
P
A
S
S
S
P
Site 26
S321
E
G
S
Q
S
P
T
S
P
A
S
S
S
P
K
Site 27
S324
Q
S
P
T
S
P
A
S
S
S
P
K
P
G
S
Site 28
S325
S
P
T
S
P
A
S
S
S
P
K
P
G
S
K
Site 29
S326
P
T
S
P
A
S
S
S
P
K
P
G
S
K
A
Site 30
S331
S
S
S
P
K
P
G
S
K
A
G
S
Q
E
A
Site 31
S335
K
P
G
S
K
A
G
S
Q
E
A
E
V
G
S
Site 32
S342
S
Q
E
A
E
V
G
S
D
G
E
R
V
A
Q
Site 33
T350
D
G
E
R
V
A
Q
T
P
D
S
S
D
G
G
Site 34
S353
R
V
A
Q
T
P
D
S
S
D
G
G
L
S
P
Site 35
S354
V
A
Q
T
P
D
S
S
D
G
G
L
S
P
S
Site 36
S359
D
S
S
D
G
G
L
S
P
S
G
E
D
E
D
Site 37
S361
S
D
G
G
L
S
P
S
G
E
D
E
D
E
D
Site 38
S375
D
Q
L
M
Y
R
L
S
Y
Q
V
Q
G
P
R
Site 39
Y376
Q
L
M
Y
R
L
S
Y
Q
V
Q
G
P
R
P
Site 40
S409
P
S
C
L
V
L
N
S
L
Q
Q
E
L
Q
K
Site 41
S448
K
G
G
V
F
V
C
S
H
G
R
A
K
M
E
Site 42
T463
G
N
I
F
R
N
L
T
Y
A
V
R
C
I
H
Site 43
Y464
N
I
F
R
N
L
T
Y
A
V
R
C
I
H
N
Site 44
Y482
I
M
L
R
N
D
I
Y
R
C
R
A
S
G
I
Site 45
S487
D
I
Y
R
C
R
A
S
G
I
F
L
R
L
E
Site 46
S518
G
V
D
I
R
K
K
S
N
P
L
C
N
Q
I
Site 47
S654
G
V
W
M
M
S
S
S
L
P
H
V
T
S
N
Site 48
S726
I
A
L
V
E
S
N
S
I
N
H
N
G
A
S
Site 49
S775
R
V
A
N
N
S
I
S
C
N
R
Q
S
G
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation