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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF223
Full Name:
Alias:
Type:
Mass (Da):
55960
Number AA:
482
UniProt ID:
Q9UK11
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
D
L
A
Q
R
K
L
Y
R
D
V
M
L
E
N
Site 2
S46
E
N
F
R
N
L
L
S
V
G
H
Q
P
F
H
Site 3
T88
K
I
Q
P
E
M
K
T
F
P
E
A
G
P
H
Site 4
S109
Q
I
W
E
E
I
A
S
D
L
T
R
P
Q
D
Site 5
S117
D
L
T
R
P
Q
D
S
T
I
K
S
S
Q
F
Site 6
T118
L
T
R
P
Q
D
S
T
I
K
S
S
Q
F
F
Site 7
S121
P
Q
D
S
T
I
K
S
S
Q
F
F
E
Q
G
Site 8
S122
Q
D
S
T
I
K
S
S
Q
F
F
E
Q
G
D
Site 9
S132
F
E
Q
G
D
A
H
S
Q
V
E
E
G
I
S
Site 10
S139
S
Q
V
E
E
G
I
S
I
M
H
T
G
Q
K
Site 11
T143
E
G
I
S
I
M
H
T
G
Q
K
P
S
N
C
Site 12
S148
M
H
T
G
Q
K
P
S
N
C
G
K
S
K
Q
Site 13
S153
K
P
S
N
C
G
K
S
K
Q
S
F
S
D
M
Site 14
S156
N
C
G
K
S
K
Q
S
F
S
D
M
S
I
F
Site 15
S158
G
K
S
K
Q
S
F
S
D
M
S
I
F
D
L
Site 16
S161
K
Q
S
F
S
D
M
S
I
F
D
L
P
Q
Q
Site 17
S171
D
L
P
Q
Q
I
R
S
A
E
K
S
H
S
C
Site 18
S175
Q
I
R
S
A
E
K
S
H
S
C
D
E
C
G
Site 19
S177
R
S
A
E
K
S
H
S
C
D
E
C
G
K
S
Site 20
S214
D
V
C
G
K
E
F
S
Q
S
L
H
L
Q
T
Site 21
S216
C
G
K
E
F
S
Q
S
L
H
L
Q
T
H
Q
Site 22
T227
Q
T
H
Q
R
V
H
T
G
E
K
P
F
K
C
Site 23
S245
G
R
G
F
R
C
R
S
A
L
T
V
H
C
K
Site 24
Y260
L
H
M
G
E
K
H
Y
N
C
E
A
C
G
R
Site 25
T283
Q
K
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 26
Y316
V
H
T
A
E
K
L
Y
K
S
E
K
Y
G
R
Site 27
S318
T
A
E
K
L
Y
K
S
E
K
Y
G
R
G
F
Site 28
Y321
K
L
Y
K
S
E
K
Y
G
R
G
F
I
D
R
Site 29
Y344
I
H
M
G
Q
K
P
Y
N
C
K
E
C
G
K
Site 30
S357
G
K
S
F
K
W
S
S
Y
L
L
V
H
Q
R
Site 31
T367
L
V
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 32
Y381
C
E
E
C
G
K
G
Y
I
S
K
S
G
L
D
Site 33
S383
E
C
G
K
G
Y
I
S
K
S
G
L
D
L
H
Site 34
S385
G
K
G
Y
I
S
K
S
G
L
D
L
H
H
R
Site 35
T395
D
L
H
H
R
A
H
T
G
E
R
P
Y
N
C
Site 36
Y400
A
H
T
G
E
R
P
Y
N
C
D
D
C
G
K
Site 37
S408
N
C
D
D
C
G
K
S
F
R
Q
A
S
S
I
Site 38
S413
G
K
S
F
R
Q
A
S
S
I
L
N
H
K
R
Site 39
S441
G
K
K
L
V
Y
R
S
Y
R
K
D
Q
Q
K
Site 40
Y442
K
K
L
V
Y
R
S
Y
R
K
D
Q
Q
K
N
Site 41
S456
N
H
S
G
E
N
P
S
K
C
E
D
C
G
K
Site 42
Y465
C
E
D
C
G
K
R
Y
K
R
R
L
N
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation