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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF225
Full Name:
Zinc finger protein 225
Alias:
Type:
Intracellular, Nucleus protein
Mass (Da):
82471
Number AA:
706
UniProt ID:
Q9UK10
International Prot ID:
IPI00007035
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
D
L
A
Q
R
K
L
Y
R
E
V
M
L
E
N
Site 2
S46
E
N
F
R
N
L
L
S
V
G
H
Q
S
L
H
Site 3
S51
L
L
S
V
G
H
Q
S
L
H
R
D
T
F
H
Site 4
T56
H
Q
S
L
H
R
D
T
F
H
F
L
K
E
E
Site 5
T88
K
I
Q
M
E
M
E
T
V
S
E
S
G
T
H
Site 6
S90
Q
M
E
M
E
T
V
S
E
S
G
T
H
E
G
Site 7
S92
E
M
E
T
V
S
E
S
G
T
H
E
G
L
F
Site 8
T94
E
T
V
S
E
S
G
T
H
E
G
L
F
S
H
Site 9
T103
E
G
L
F
S
H
Q
T
W
E
Q
I
S
S
D
Site 10
S109
Q
T
W
E
Q
I
S
S
D
L
T
R
F
Q
D
Site 11
T112
E
Q
I
S
S
D
L
T
R
F
Q
D
S
M
V
Site 12
S117
D
L
T
R
F
Q
D
S
M
V
N
S
F
Q
F
Site 13
S121
F
Q
D
S
M
V
N
S
F
Q
F
S
K
Q
D
Site 14
S148
I
H
V
R
Q
K
P
S
E
G
R
T
C
K
K
Site 15
T152
Q
K
P
S
E
G
R
T
C
K
K
S
F
S
D
Site 16
S156
E
G
R
T
C
K
K
S
F
S
D
V
S
V
L
Site 17
S158
R
T
C
K
K
S
F
S
D
V
S
V
L
D
L
Site 18
S161
K
K
S
F
S
D
V
S
V
L
D
L
H
Q
Q
Site 19
S171
D
L
H
Q
Q
L
Q
S
R
E
K
S
H
T
C
Site 20
S175
Q
L
Q
S
R
E
K
S
H
T
C
D
E
C
G
Site 21
T177
Q
S
R
E
K
S
H
T
C
D
E
C
G
K
S
Site 22
S189
G
K
S
F
C
Y
S
S
A
L
R
I
H
Q
R
Site 23
Y204
V
H
M
G
E
K
L
Y
N
C
D
V
C
G
K
Site 24
S217
G
K
E
F
N
Q
S
S
H
L
Q
I
H
Q
R
Site 25
T227
Q
I
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 26
S242
E
Q
C
G
K
G
F
S
R
R
S
G
L
Y
V
Site 27
S245
G
K
G
F
S
R
R
S
G
L
Y
V
H
R
K
Site 28
Y248
F
S
R
R
S
G
L
Y
V
H
R
K
L
H
T
Site 29
S273
G
K
A
F
I
H
D
S
Q
L
Q
E
H
Q
R
Site 30
T283
Q
E
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 31
S307
R
A
N
L
N
R
H
S
M
V
H
M
R
E
K
Site 32
T320
E
K
P
F
R
C
D
T
C
G
K
S
F
G
L
Site 33
S324
R
C
D
T
C
G
K
S
F
G
L
K
S
A
L
Site 34
S329
G
K
S
F
G
L
K
S
A
L
N
S
H
R
M
Site 35
S333
G
L
K
S
A
L
N
S
H
R
M
V
H
T
G
Site 36
Y355
E
C
G
K
R
F
I
Y
R
Q
D
L
Y
K
H
Site 37
Y360
F
I
Y
R
Q
D
L
Y
K
H
Q
I
D
H
T
Site 38
T367
Y
K
H
Q
I
D
H
T
G
E
K
P
Y
N
C
Site 39
Y372
D
H
T
G
E
K
P
Y
N
C
K
E
C
G
K
Site 40
S385
G
K
S
F
R
W
A
S
G
L
S
R
H
V
R
Site 41
S388
F
R
W
A
S
G
L
S
R
H
V
R
V
H
S
Site 42
S395
S
R
H
V
R
V
H
S
G
E
T
T
F
K
C
Site 43
T399
R
V
H
S
G
E
T
T
F
K
C
E
E
C
G
Site 44
T411
E
C
G
K
G
F
Y
T
N
S
Q
R
Y
S
H
Site 45
S413
G
K
G
F
Y
T
N
S
Q
R
Y
S
H
Q
R
Site 46
S417
Y
T
N
S
Q
R
Y
S
H
Q
R
A
H
S
G
Site 47
S423
Y
S
H
Q
R
A
H
S
G
E
K
P
Y
R
C
Site 48
Y428
A
H
S
G
E
K
P
Y
R
C
E
E
C
G
K
Site 49
Y437
C
E
E
C
G
K
G
Y
K
R
R
L
D
L
D
Site 50
Y456
V
H
R
G
E
K
P
Y
N
C
K
E
C
G
K
Site 51
S479
L
N
H
Q
R
I
H
S
G
E
K
P
F
K
C
Site 52
T494
E
E
C
G
K
R
F
T
Q
N
S
Q
L
Y
T
Site 53
S497
G
K
R
F
T
Q
N
S
Q
L
Y
T
H
R
R
Site 54
Y500
F
T
Q
N
S
Q
L
Y
T
H
R
R
V
H
S
Site 55
T501
T
Q
N
S
Q
L
Y
T
H
R
R
V
H
S
G
Site 56
S507
Y
T
H
R
R
V
H
S
G
E
K
P
F
K
C
Site 57
T522
E
E
C
G
K
R
F
T
Q
N
S
Q
L
Y
S
Site 58
S525
G
K
R
F
T
Q
N
S
Q
L
Y
S
H
R
R
Site 59
Y528
F
T
Q
N
S
Q
L
Y
S
H
R
R
V
H
T
Site 60
S529
T
Q
N
S
Q
L
Y
S
H
R
R
V
H
T
G
Site 61
T535
Y
S
H
R
R
V
H
T
G
V
K
P
Y
K
C
Site 62
T563
D
M
H
Q
R
V
H
T
G
E
R
P
Y
N
C
Site 63
Y568
V
H
T
G
E
R
P
Y
N
C
K
E
C
G
K
Site 64
S576
N
C
K
E
C
G
K
S
F
S
R
A
S
S
I
Site 65
S578
K
E
C
G
K
S
F
S
R
A
S
S
I
L
N
Site 66
S581
G
K
S
F
S
R
A
S
S
I
L
N
H
K
R
Site 67
S582
K
S
F
S
R
A
S
S
I
L
N
H
K
R
L
Site 68
T606
E
E
C
G
K
R
F
T
E
N
S
Q
L
H
S
Site 69
S609
G
K
R
F
T
E
N
S
Q
L
H
S
H
Q
R
Site 70
S613
T
E
N
S
Q
L
H
S
H
Q
R
V
H
T
G
Site 71
T619
H
S
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 72
S637
G
K
S
F
R
W
A
S
T
H
L
T
H
Q
R
Site 73
T641
R
W
A
S
T
H
L
T
H
Q
R
L
H
S
R
Site 74
S647
L
T
H
Q
R
L
H
S
R
E
K
L
L
Q
C
Site 75
S664
C
G
K
S
I
V
H
S
S
C
L
K
D
Q
Q
Site 76
S665
G
K
S
I
V
H
S
S
C
L
K
D
Q
Q
R
Site 77
S675
K
D
Q
Q
R
D
Q
S
G
E
K
T
S
K
C
Site 78
T679
R
D
Q
S
G
E
K
T
S
K
C
E
D
C
G
Site 79
Y689
C
E
D
C
G
K
R
Y
K
R
R
L
N
L
D
Site 80
T697
K
R
R
L
N
L
D
T
L
L
S
L
F
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation