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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF180
Full Name:
Zinc finger protein 180
Alias:
HHZ168; Z180; ZN180
Type:
Transcription factor
Mass (Da):
79111
Number AA:
692
UniProt ID:
Q9UJW8
International Prot ID:
IPI00001684
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
R
A
C
A
G
S
T
R
E
A
G
S
G
Site 2
S13
G
S
T
R
E
A
G
S
G
A
Q
D
L
S
T
Site 3
T20
S
G
A
Q
D
L
S
T
L
L
C
L
E
E
S
Site 4
S27
T
L
L
C
L
E
E
S
M
E
E
Q
D
E
K
Site 5
S46
P
K
A
C
A
Q
D
S
F
L
P
Q
E
I
I
Site 6
T61
I
K
V
E
G
E
D
T
G
S
L
T
I
P
S
Site 7
S63
V
E
G
E
D
T
G
S
L
T
I
P
S
Q
E
Site 8
T65
G
E
D
T
G
S
L
T
I
P
S
Q
E
G
V
Site 9
S68
T
G
S
L
T
I
P
S
Q
E
G
V
N
F
K
Site 10
T78
G
V
N
F
K
I
V
T
V
D
F
T
R
E
E
Site 11
T82
K
I
V
T
V
D
F
T
R
E
E
Q
G
T
W
Site 12
T88
F
T
R
E
E
Q
G
T
W
N
P
A
Q
R
T
Site 13
S122
T
A
V
G
K
K
D
S
T
S
K
Q
R
I
F
Site 14
S124
V
G
K
K
D
S
T
S
K
Q
R
I
F
D
E
Site 15
T143
G
V
K
I
E
R
F
T
R
D
D
P
W
L
S
Site 16
S150
T
R
D
D
P
W
L
S
S
C
E
E
V
D
D
Site 17
S151
R
D
D
P
W
L
S
S
C
E
E
V
D
D
C
Site 18
S192
I
H
E
R
V
C
K
S
D
E
T
G
E
K
S
Site 19
T195
R
V
C
K
S
D
E
T
G
E
K
S
G
L
N
Site 20
S199
S
D
E
T
G
E
K
S
G
L
N
S
S
L
F
Site 21
S203
G
E
K
S
G
L
N
S
S
L
F
S
S
P
V
Site 22
S204
E
K
S
G
L
N
S
S
L
F
S
S
P
V
I
Site 23
Y246
I
N
E
N
E
T
L
Y
E
N
N
E
C
G
K
Site 24
T268
I
Q
F
T
R
T
Q
T
K
D
K
C
Y
G
F
Site 25
Y273
T
Q
T
K
D
K
C
Y
G
F
S
D
R
I
Q
Site 26
S281
G
F
S
D
R
I
Q
S
F
C
H
G
T
P
L
Site 27
T300
K
I
H
G
G
G
K
T
F
D
F
K
E
C
G
Site 28
S315
Q
V
L
N
P
K
I
S
H
N
E
Q
Q
R
I
Site 29
S327
Q
R
I
P
F
E
E
S
Q
Y
K
C
S
E
T
Site 30
Y329
I
P
F
E
E
S
Q
Y
K
C
S
E
T
S
H
Site 31
S332
E
E
S
Q
Y
K
C
S
E
T
S
H
S
S
S
Site 32
T334
S
Q
Y
K
C
S
E
T
S
H
S
S
S
L
T
Site 33
S335
Q
Y
K
C
S
E
T
S
H
S
S
S
L
T
Q
Site 34
S337
K
C
S
E
T
S
H
S
S
S
L
T
Q
N
M
Site 35
S339
S
E
T
S
H
S
S
S
L
T
Q
N
M
R
N
Site 36
T341
T
S
H
S
S
S
L
T
Q
N
M
R
N
N
S
Site 37
S348
T
Q
N
M
R
N
N
S
E
E
K
P
F
E
C
Site 38
S363
N
Q
C
G
K
S
F
S
W
S
S
H
L
V
A
Site 39
S366
G
K
S
F
S
W
S
S
H
L
V
A
H
Q
R
Site 40
T374
H
L
V
A
H
Q
R
T
H
T
G
E
K
P
Y
Site 41
T376
V
A
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 42
Y381
T
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 43
S384
G
E
K
P
Y
E
C
S
E
C
G
K
S
F
S
Site 44
S389
E
C
S
E
C
G
K
S
F
S
R
S
S
H
L
Site 45
S391
S
E
C
G
K
S
F
S
R
S
S
H
L
V
S
Site 46
S393
C
G
K
S
F
S
R
S
S
H
L
V
S
H
Q
Site 47
S394
G
K
S
F
S
R
S
S
H
L
V
S
H
Q
R
Site 48
S398
S
R
S
S
H
L
V
S
H
Q
R
T
H
T
G
Site 49
T402
H
L
V
S
H
Q
R
T
H
T
G
E
K
P
Y
Site 50
T404
V
S
H
Q
R
T
H
T
G
E
K
P
Y
R
C
Site 51
S417
R
C
N
Q
C
G
K
S
F
S
Q
S
Y
V
L
Site 52
Y422
G
K
S
F
S
Q
S
Y
V
L
V
V
H
Q
R
Site 53
T430
V
L
V
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 54
T432
V
V
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 55
Y437
T
H
T
G
E
K
P
Y
E
C
N
Q
C
G
K
Site 56
S449
C
G
K
S
F
R
Q
S
Y
K
L
I
A
H
Q
Site 57
Y450
G
K
S
F
R
Q
S
Y
K
L
I
A
H
Q
R
Site 58
T458
K
L
I
A
H
Q
R
T
H
T
G
E
K
P
Y
Site 59
T460
I
A
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 60
T488
I
A
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 61
Y493
I
H
T
G
E
K
P
Y
E
C
N
Q
C
G
K
Site 62
S501
E
C
N
Q
C
G
K
S
F
S
Q
S
Y
K
L
Site 63
S503
N
Q
C
G
K
S
F
S
Q
S
Y
K
L
V
A
Site 64
S505
C
G
K
S
F
S
Q
S
Y
K
L
V
A
H
Q
Site 65
T514
K
L
V
A
H
Q
R
T
H
T
G
E
K
P
F
Site 66
T516
V
A
H
Q
R
T
H
T
G
E
K
P
F
E
C
Site 67
S531
N
Q
C
G
K
S
F
S
W
S
S
Q
L
V
A
Site 68
S533
C
G
K
S
F
S
W
S
S
Q
L
V
A
H
Q
Site 69
S534
G
K
S
F
S
W
S
S
Q
L
V
A
H
Q
R
Site 70
T542
Q
L
V
A
H
Q
R
T
H
T
G
E
K
P
Y
Site 71
S552
G
E
K
P
Y
E
C
S
E
C
G
K
S
F
N
Site 72
S557
E
C
S
E
C
G
K
S
F
N
R
S
S
H
L
Site 73
S562
G
K
S
F
N
R
S
S
H
L
V
M
H
Q
R
Site 74
T572
V
M
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 75
S585
E
C
N
Q
C
G
K
S
F
S
Q
S
Y
V
L
Site 76
Y605
T
H
T
G
E
K
P
Y
E
C
S
Q
C
G
K
Site 77
S608
G
E
K
P
Y
E
C
S
Q
C
G
K
S
F
R
Site 78
S613
E
C
S
Q
C
G
K
S
F
R
Q
S
S
C
L
Site 79
S617
C
G
K
S
F
R
Q
S
S
C
L
T
Q
H
Q
Site 80
S618
G
K
S
F
R
Q
S
S
C
L
T
Q
H
Q
R
Site 81
T621
F
R
Q
S
S
C
L
T
Q
H
Q
R
T
H
T
Site 82
T626
C
L
T
Q
H
Q
R
T
H
T
G
E
K
P
F
Site 83
T628
T
Q
H
Q
R
T
H
T
G
E
K
P
F
E
C
Site 84
T641
E
C
N
Q
C
G
K
T
F
S
L
S
A
R
L
Site 85
S643
N
Q
C
G
K
T
F
S
L
S
A
R
L
I
V
Site 86
T654
R
L
I
V
H
Q
R
T
H
T
G
E
K
P
F
Site 87
T656
I
V
H
Q
R
T
H
T
G
E
K
P
F
T
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation