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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERRFI1
Full Name:
ERBB receptor feedback inhibitor 1
Alias:
ERRFI; GENE-33; MIG6; MIG-6; Mitogen-inducible gene 6 protein; RALT
Type:
Inhibitor protein
Mass (Da):
50560
Number AA:
462
UniProt ID:
Q9UJM3
International Prot ID:
IPI00004399
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005100
PhosphoSite+
KinaseNET
Biological Process:
GO:0006950
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
E
I
R
V
P
L
K
T
G
F
L
H
N
G
R
Site 2
T32
A
M
G
N
M
R
K
T
Y
W
S
S
R
S
E
Site 3
Y33
M
G
N
M
R
K
T
Y
W
S
S
R
S
E
F
Site 4
S35
N
M
R
K
T
Y
W
S
S
R
S
E
F
K
N
Site 5
S38
K
T
Y
W
S
S
R
S
E
F
K
N
N
F
L
Site 6
Y54
I
D
P
I
T
M
A
Y
S
L
N
S
S
A
Q
Site 7
S55
D
P
I
T
M
A
Y
S
L
N
S
S
A
Q
E
Site 8
S59
M
A
Y
S
L
N
S
S
A
Q
E
R
L
I
P
Site 9
S71
L
I
P
L
G
H
A
S
K
S
A
P
M
N
G
Site 10
S73
P
L
G
H
A
S
K
S
A
P
M
N
G
H
C
Site 11
S87
C
F
A
E
N
G
P
S
Q
K
S
S
L
P
P
Site 12
S90
E
N
G
P
S
Q
K
S
S
L
P
P
L
L
I
Site 13
S91
N
G
P
S
Q
K
S
S
L
P
P
L
L
I
P
Site 14
S100
P
P
L
L
I
P
P
S
E
N
L
G
P
H
E
Site 15
S126
T
V
N
G
V
C
A
S
T
P
P
L
T
P
I
Site 16
T127
V
N
G
V
C
A
S
T
P
P
L
T
P
I
K
Site 17
T131
C
A
S
T
P
P
L
T
P
I
K
N
S
P
S
Site 18
S136
P
L
T
P
I
K
N
S
P
S
L
F
P
C
A
Site 19
S150
A
P
L
C
E
R
G
S
R
P
L
P
P
L
P
Site 20
S163
L
P
I
S
E
A
L
S
L
D
D
T
D
C
E
Site 21
T167
E
A
L
S
L
D
D
T
D
C
E
V
E
F
L
Site 22
S177
E
V
E
F
L
T
S
S
D
T
D
F
L
L
E
Site 23
T179
E
F
L
T
S
S
D
T
D
F
L
L
E
D
S
Site 24
S186
T
D
F
L
L
E
D
S
T
L
S
D
F
K
Y
Site 25
T187
D
F
L
L
E
D
S
T
L
S
D
F
K
Y
D
Site 26
Y193
S
T
L
S
D
F
K
Y
D
V
P
G
R
R
S
Site 27
S200
Y
D
V
P
G
R
R
S
F
R
G
C
G
Q
I
Site 28
Y209
R
G
C
G
Q
I
N
Y
A
Y
F
D
T
P
A
Site 29
Y211
C
G
Q
I
N
Y
A
Y
F
D
T
P
A
V
S
Site 30
S223
A
V
S
A
A
D
L
S
Y
V
S
D
Q
N
G
Site 31
Y224
V
S
A
A
D
L
S
Y
V
S
D
Q
N
G
G
Site 32
S226
A
A
D
L
S
Y
V
S
D
Q
N
G
G
V
P
Site 33
T242
P
N
P
P
P
P
Q
T
H
R
R
L
R
R
S
Site 34
S249
T
H
R
R
L
R
R
S
H
S
G
P
A
G
S
Site 35
S251
R
R
L
R
R
S
H
S
G
P
A
G
S
F
N
Site 36
S256
S
H
S
G
P
A
G
S
F
N
K
P
A
I
R
Site 37
S273
N
C
C
I
H
R
A
S
P
N
S
D
E
D
K
Site 38
S276
I
H
R
A
S
P
N
S
D
E
D
K
P
E
V
Site 39
Y298
P
R
P
V
K
P
D
Y
R
R
W
S
A
E
V
Site 40
S302
K
P
D
Y
R
R
W
S
A
E
V
T
S
S
T
Site 41
T306
R
R
W
S
A
E
V
T
S
S
T
Y
S
D
E
Site 42
S307
R
W
S
A
E
V
T
S
S
T
Y
S
D
E
D
Site 43
S311
E
V
T
S
S
T
Y
S
D
E
D
R
P
P
K
Site 44
S326
V
P
P
R
E
P
L
S
P
S
N
S
R
T
P
Site 45
S328
P
R
E
P
L
S
P
S
N
S
R
T
P
S
P
Site 46
S330
E
P
L
S
P
S
N
S
R
T
P
S
P
K
S
Site 47
T332
L
S
P
S
N
S
R
T
P
S
P
K
S
L
P
Site 48
S334
P
S
N
S
R
T
P
S
P
K
S
L
P
S
Y
Site 49
S337
S
R
T
P
S
P
K
S
L
P
S
Y
L
N
G
Site 50
S340
P
S
P
K
S
L
P
S
Y
L
N
G
V
M
P
Site 51
Y341
S
P
K
S
L
P
S
Y
L
N
G
V
M
P
P
Site 52
T349
L
N
G
V
M
P
P
T
Q
S
F
A
P
D
P
Site 53
S351
G
V
M
P
P
T
Q
S
F
A
P
D
P
K
Y
Site 54
Y358
S
F
A
P
D
P
K
Y
V
S
S
K
A
L
Q
Site 55
S369
K
A
L
Q
R
Q
N
S
E
G
S
A
S
K
V
Site 56
S374
Q
N
S
E
G
S
A
S
K
V
P
C
I
L
P
Site 57
S390
I
E
N
G
K
K
V
S
S
T
H
Y
Y
L
L
Site 58
S391
E
N
G
K
K
V
S
S
T
H
Y
Y
L
L
P
Site 59
T392
N
G
K
K
V
S
S
T
H
Y
Y
L
L
P
E
Site 60
Y394
K
K
V
S
S
T
H
Y
Y
L
L
P
E
R
P
Site 61
Y395
K
V
S
S
T
H
Y
Y
L
L
P
E
R
P
P
Site 62
Y403
L
L
P
E
R
P
P
Y
L
D
K
Y
E
K
F
Site 63
Y407
R
P
P
Y
L
D
K
Y
E
K
F
F
R
E
A
Site 64
T417
F
F
R
E
A
E
E
T
N
G
G
A
Q
I
Q
Site 65
S434
P
A
D
C
G
I
S
S
A
T
E
K
P
D
S
Site 66
S441
S
A
T
E
K
P
D
S
K
T
K
M
D
L
G
Site 67
T443
T
E
K
P
D
S
K
T
K
M
D
L
G
G
H
Site 68
S457
H
V
K
R
K
H
L
S
Y
V
V
S
P
_
_
Site 69
Y458
V
K
R
K
H
L
S
Y
V
V
S
P
_
_
_
Site 70
S461
K
H
L
S
Y
V
V
S
P
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation