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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRMT6
Full Name:
tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6
Alias:
CGI-09; KIAA1153; TRM6; TRNA(m1A58)-methyltransferase subunit TRM6
Type:
Unknown function
Mass (Da):
55799
Number AA:
497
UniProt ID:
Q9UJA5
International Prot ID:
IPI00099311
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003743
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0006399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T46
V
Q
R
R
K
K
V
T
F
E
K
Q
W
F
Y
Site 2
Y53
T
F
E
K
Q
W
F
Y
L
D
N
V
I
G
H
Site 3
T87
R
E
E
P
T
A
E
T
K
E
A
G
T
D
N
Site 4
T92
A
E
T
K
E
A
G
T
D
N
R
N
I
V
D
Site 5
S103
N
I
V
D
D
G
K
S
Q
K
L
T
Q
D
D
Site 6
T107
D
G
K
S
Q
K
L
T
Q
D
D
I
K
A
L
Site 7
T134
Q
L
I
E
N
S
T
T
F
R
D
K
T
E
F
Site 8
T139
S
T
T
F
R
D
K
T
E
F
A
Q
D
K
Y
Site 9
Y146
T
E
F
A
Q
D
K
Y
I
K
K
K
K
K
K
Site 10
Y154
I
K
K
K
K
K
K
Y
E
A
I
I
T
V
V
Site 11
T159
K
K
Y
E
A
I
I
T
V
V
K
P
S
T
R
Site 12
S164
I
I
T
V
V
K
P
S
T
R
I
L
S
I
M
Site 13
T165
I
T
V
V
K
P
S
T
R
I
L
S
I
M
Y
Site 14
S169
K
P
S
T
R
I
L
S
I
M
Y
Y
A
R
E
Site 15
Y172
T
R
I
L
S
I
M
Y
Y
A
R
E
P
G
K
Site 16
Y173
R
I
L
S
I
M
Y
Y
A
R
E
P
G
K
I
Site 17
Y185
G
K
I
N
H
M
R
Y
D
T
L
A
Q
M
L
Site 18
T187
I
N
H
M
R
Y
D
T
L
A
Q
M
L
T
L
Site 19
T193
D
T
L
A
Q
M
L
T
L
G
N
I
R
A
G
Site 20
S226
E
R
M
G
G
F
G
S
I
I
Q
L
Y
P
G
Site 21
Y231
F
G
S
I
I
Q
L
Y
P
G
G
G
P
V
R
Site 22
Y255
K
S
F
L
S
G
L
Y
E
F
P
L
N
K
V
Site 23
S271
S
L
L
H
G
T
F
S
A
K
M
L
S
S
E
Site 24
S276
T
F
S
A
K
M
L
S
S
E
P
K
D
S
A
Site 25
S277
F
S
A
K
M
L
S
S
E
P
K
D
S
A
L
Site 26
S282
L
S
S
E
P
K
D
S
A
L
V
E
E
S
N
Site 27
T291
L
V
E
E
S
N
G
T
L
E
E
K
Q
A
S
Site 28
S298
T
L
E
E
K
Q
A
S
E
Q
E
N
E
D
S
Site 29
S305
S
E
Q
E
N
E
D
S
M
A
E
A
P
E
S
Site 30
S312
S
M
A
E
A
P
E
S
N
H
P
E
D
Q
E
Site 31
T320
N
H
P
E
D
Q
E
T
M
E
T
I
S
Q
D
Site 32
T323
E
D
Q
E
T
M
E
T
I
S
Q
D
P
E
H
Site 33
S325
Q
E
T
M
E
T
I
S
Q
D
P
E
H
K
G
Site 34
S338
K
G
P
K
E
R
G
S
K
K
D
Y
I
Q
E
Site 35
Y342
E
R
G
S
K
K
D
Y
I
Q
E
K
Q
R
R
Site 36
Y400
P
S
R
P
F
V
V
Y
C
Q
Y
K
E
P
L
Site 37
S426
G
V
I
N
L
R
L
S
E
T
W
L
R
N
Y
Site 38
Y433
S
E
T
W
L
R
N
Y
Q
V
L
P
D
R
S
Site 39
S440
Y
Q
V
L
P
D
R
S
H
P
K
L
L
M
S
Site 40
S469
D
N
L
K
A
D
T
S
L
K
S
N
A
S
T
Site 41
S472
K
A
D
T
S
L
K
S
N
A
S
T
L
E
S
Site 42
S475
T
S
L
K
S
N
A
S
T
L
E
S
H
E
T
Site 43
T476
S
L
K
S
N
A
S
T
L
E
S
H
E
T
E
Site 44
S479
S
N
A
S
T
L
E
S
H
E
T
E
E
P
A
Site 45
T482
S
T
L
E
S
H
E
T
E
E
P
A
A
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation