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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STAG3
Full Name:
Cohesin subunit SA-3
Alias:
SCC3 3; SCC3 homolog 3; Stromal antigen 3; Stromalin 3
Type:
Synaptonemal complex, Nucleus protein
Mass (Da):
139034
Number AA:
1225
UniProt ID:
Q9UJ98
International Prot ID:
IPI00018353
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0007059
GO:0007130
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
S
S
P
L
Q
R
A
V
G
Site 2
T12
L
Q
R
A
V
G
D
T
K
R
A
L
S
A
S
Site 3
S17
G
D
T
K
R
A
L
S
A
S
S
S
S
S
A
Site 4
S19
T
K
R
A
L
S
A
S
S
S
S
S
A
S
L
Site 5
S20
K
R
A
L
S
A
S
S
S
S
S
A
S
L
P
Site 6
S21
R
A
L
S
A
S
S
S
S
S
A
S
L
P
F
Site 7
S22
A
L
S
A
S
S
S
S
S
A
S
L
P
F
D
Site 8
S23
L
S
A
S
S
S
S
S
A
S
L
P
F
D
D
Site 9
S25
A
S
S
S
S
S
A
S
L
P
F
D
D
R
D
Site 10
S33
L
P
F
D
D
R
D
S
N
H
T
S
E
G
N
Site 11
T36
D
D
R
D
S
N
H
T
S
E
G
N
G
D
S
Site 12
S37
D
R
D
S
N
H
T
S
E
G
N
G
D
S
L
Site 13
S43
T
S
E
G
N
G
D
S
L
L
A
D
E
D
T
Site 14
T50
S
L
L
A
D
E
D
T
D
F
E
D
S
L
N
Site 15
S55
E
D
T
D
F
E
D
S
L
N
R
N
V
K
K
Site 16
T71
A
A
K
R
P
P
K
T
T
P
V
A
K
H
P
Site 17
T72
A
K
R
P
P
K
T
T
P
V
A
K
H
P
K
Site 18
S82
A
K
H
P
K
K
G
S
R
V
V
H
R
H
S
Site 19
S89
S
R
V
V
H
R
H
S
R
K
Q
S
E
P
P
Site 20
S93
H
R
H
S
R
K
Q
S
E
P
P
A
N
D
L
Site 21
S109
N
A
V
K
A
A
K
S
D
M
Q
S
L
V
D
Site 22
S113
A
A
K
S
D
M
Q
S
L
V
D
E
W
L
D
Site 23
S121
L
V
D
E
W
L
D
S
Y
K
Q
D
Q
D
A
Site 24
Y122
V
D
E
W
L
D
S
Y
K
Q
D
Q
D
A
G
Site 25
S156
P
E
M
F
K
K
M
S
N
S
E
I
I
Q
H
Site 26
Y175
F
N
E
D
S
G
D
Y
P
L
I
A
P
G
P
Site 27
S183
P
L
I
A
P
G
P
S
W
K
K
F
Q
G
S
Site 28
Y208
Q
C
Q
Y
S
L
L
Y
D
G
F
P
M
D
D
Site 29
T221
D
D
L
I
S
L
L
T
G
L
S
D
S
Q
V
Site 30
S226
L
L
T
G
L
S
D
S
Q
V
R
A
F
R
H
Site 31
T234
Q
V
R
A
F
R
H
T
S
T
L
A
A
M
K
Site 32
T236
R
A
F
R
H
T
S
T
L
A
A
M
K
L
M
Site 33
S254
V
K
V
A
L
Q
L
S
V
H
Q
D
N
N
Q
Site 34
Y264
Q
D
N
N
Q
R
Q
Y
E
A
E
R
N
K
G
Site 35
S282
R
A
P
E
R
L
E
S
L
L
E
K
R
K
E
Site 36
Y313
R
G
V
F
V
H
R
Y
R
D
V
L
P
E
I
Site 37
Y335
I
G
C
W
M
Q
S
Y
S
T
S
F
L
T
D
Site 38
S338
W
M
Q
S
Y
S
T
S
F
L
T
D
S
Y
L
Site 39
T341
S
Y
S
T
S
F
L
T
D
S
Y
L
K
Y
I
Site 40
S343
S
T
S
F
L
T
D
S
Y
L
K
Y
I
G
W
Site 41
Y344
T
S
F
L
T
D
S
Y
L
K
Y
I
G
W
T
Site 42
Y347
L
T
D
S
Y
L
K
Y
I
G
W
T
L
H
D
Site 43
Y371
V
K
A
L
K
G
L
Y
G
N
R
D
L
T
T
Site 44
T377
L
Y
G
N
R
D
L
T
T
R
L
E
L
F
T
Site 45
T384
T
T
R
L
E
L
F
T
S
R
F
K
D
R
M
Site 46
S385
T
R
L
E
L
F
T
S
R
F
K
D
R
M
V
Site 47
S393
R
F
K
D
R
M
V
S
M
V
M
D
R
E
Y
Site 48
T422
K
N
M
E
G
V
L
T
D
A
D
C
E
S
V
Site 49
Y430
D
A
D
C
E
S
V
Y
P
V
V
Y
A
S
H
Site 50
Y449
S
A
A
G
E
F
L
Y
W
K
L
F
Y
P
E
Site 51
S470
G
G
R
E
Q
R
Q
S
P
G
A
Q
R
T
F
Site 52
T476
Q
S
P
G
A
Q
R
T
F
F
Q
L
L
L
S
Site 53
Y496
E
L
H
D
H
A
A
Y
L
V
D
S
L
W
D
Site 54
S517
K
D
W
E
G
L
T
S
L
L
L
E
K
D
Q
Site 55
S546
V
S
S
A
R
Q
A
S
E
G
H
P
P
V
G
Site 56
T556
H
P
P
V
G
R
V
T
G
R
K
G
L
T
S
Site 57
S563
T
G
R
K
G
L
T
S
K
E
R
K
T
Q
A
Site 58
T568
L
T
S
K
E
R
K
T
Q
A
D
D
R
V
K
Site 59
S592
P
Q
L
L
A
K
F
S
A
D
A
E
K
V
T
Site 60
Y613
S
C
F
D
L
H
I
Y
C
T
G
R
L
E
K
Site 61
T615
F
D
L
H
I
Y
C
T
G
R
L
E
K
H
L
Site 62
S661
N
P
E
F
T
F
F
S
R
A
D
F
A
R
S
Site 63
S668
S
R
A
D
F
A
R
S
Q
L
V
D
L
L
T
Site 64
T675
S
Q
L
V
D
L
L
T
D
R
F
Q
Q
E
L
Site 65
S688
E
L
E
E
L
L
Q
S
S
F
L
D
E
D
E
Site 66
S689
L
E
E
L
L
Q
S
S
F
L
D
E
D
E
V
Site 67
Y697
F
L
D
E
D
E
V
Y
N
L
A
A
T
L
K
Site 68
S707
A
A
T
L
K
R
L
S
A
F
Y
N
T
H
D
Site 69
Y710
L
K
R
L
S
A
F
Y
N
T
H
D
L
T
R
Site 70
T712
R
L
S
A
F
Y
N
T
H
D
L
T
R
W
E
Site 71
Y721
D
L
T
R
W
E
L
Y
E
P
C
C
Q
L
L
Site 72
S761
L
W
T
L
T
H
I
S
K
S
D
A
S
Q
K
Site 73
S763
T
L
T
H
I
S
K
S
D
A
S
Q
K
Q
L
Site 74
S766
H
I
S
K
S
D
A
S
Q
K
Q
L
S
S
L
Site 75
S771
D
A
S
Q
K
Q
L
S
S
L
R
D
R
M
V
Site 76
S772
A
S
Q
K
Q
L
S
S
L
R
D
R
M
V
A
Site 77
S789
E
L
C
Q
S
C
L
S
D
V
D
T
E
I
Q
Site 78
T793
S
C
L
S
D
V
D
T
E
I
Q
E
Q
A
F
Site 79
S854
I
Q
P
G
D
L
G
S
G
D
S
Q
E
D
H
Site 80
S857
G
D
L
G
S
G
D
S
Q
E
D
H
L
Q
I
Site 81
Y898
A
S
D
V
F
K
H
Y
N
K
F
Y
N
D
Y
Site 82
Y902
F
K
H
Y
N
K
F
Y
N
D
Y
G
D
I
I
Site 83
Y905
Y
N
K
F
Y
N
D
Y
G
D
I
I
K
E
T
Site 84
T912
Y
G
D
I
I
K
E
T
L
T
R
A
R
Q
I
Site 85
S922
R
A
R
Q
I
D
R
S
H
C
S
R
I
L
L
Site 86
T937
L
S
L
K
Q
L
Y
T
E
L
L
Q
E
H
G
Site 87
S967
L
A
R
R
F
A
L
S
F
G
P
Q
Q
L
Q
Site 88
S990
H
K
E
G
I
Q
F
S
L
S
E
L
P
P
A
Site 89
S992
E
G
I
Q
F
S
L
S
E
L
P
P
A
G
S
Site 90
S999
S
E
L
P
P
A
G
S
S
N
Q
P
P
N
L
Site 91
S1000
E
L
P
P
A
G
S
S
N
Q
P
P
N
L
A
Site 92
S1016
L
E
L
L
S
E
F
S
P
R
L
F
H
Q
D
Site 93
S1029
Q
D
K
Q
L
L
L
S
Y
L
E
K
C
L
Q
Site 94
Y1030
D
K
Q
L
L
L
S
Y
L
E
K
C
L
Q
H
Site 95
Y1052
P
W
G
P
V
T
T
Y
C
H
S
L
S
P
V
Site 96
S1055
P
V
T
T
Y
C
H
S
L
S
P
V
E
N
T
Site 97
S1057
T
T
Y
C
H
S
L
S
P
V
E
N
T
A
E
Site 98
T1062
S
L
S
P
V
E
N
T
A
E
T
S
P
Q
V
Site 99
S1066
V
E
N
T
A
E
T
S
P
Q
V
L
P
S
S
Site 100
S1073
S
P
Q
V
L
P
S
S
K
R
R
R
V
E
G
Site 101
S1090
K
P
N
R
E
D
V
S
S
S
Q
E
E
S
L
Site 102
S1091
P
N
R
E
D
V
S
S
S
Q
E
E
S
L
Q
Site 103
S1092
N
R
E
D
V
S
S
S
Q
E
E
S
L
Q
L
Site 104
S1096
V
S
S
S
Q
E
E
S
L
Q
L
N
S
I
P
Site 105
S1101
E
E
S
L
Q
L
N
S
I
P
P
T
P
T
L
Site 106
T1105
Q
L
N
S
I
P
P
T
P
T
L
T
S
T
A
Site 107
T1111
P
T
P
T
L
T
S
T
A
V
K
S
R
Q
P
Site 108
S1131
E
M
E
E
E
D
G
S
E
L
D
F
A
Q
G
Site 109
T1144
Q
G
Q
P
V
A
G
T
E
R
S
R
F
L
G
Site 110
Y1154
S
R
F
L
G
P
Q
Y
F
Q
T
P
H
N
P
Site 111
T1157
L
G
P
Q
Y
F
Q
T
P
H
N
P
S
G
P
Site 112
S1162
F
Q
T
P
H
N
P
S
G
P
G
L
G
N
Q
Site 113
S1174
G
N
Q
L
M
R
L
S
L
M
E
E
D
E
E
Site 114
S1190
E
L
E
I
Q
D
E
S
N
E
E
R
Q
D
T
Site 115
T1197
S
N
E
E
R
Q
D
T
D
M
Q
A
S
S
Y
Site 116
S1202
Q
D
T
D
M
Q
A
S
S
Y
S
S
T
S
E
Site 117
S1203
D
T
D
M
Q
A
S
S
Y
S
S
T
S
E
R
Site 118
Y1204
T
D
M
Q
A
S
S
Y
S
S
T
S
E
R
G
Site 119
S1206
M
Q
A
S
S
Y
S
S
T
S
E
R
G
L
D
Site 120
T1207
Q
A
S
S
Y
S
S
T
S
E
R
G
L
D
L
Site 121
S1208
A
S
S
Y
S
S
T
S
E
R
G
L
D
L
L
Site 122
S1217
R
G
L
D
L
L
D
S
T
E
L
D
I
E
D
Site 123
T1218
G
L
D
L
L
D
S
T
E
L
D
I
E
D
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation