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Updated November 2019
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Protein Info
Short Name:
BAZ1B
Full Name:
Bromodomain adjacent to zinc finger domain protein 1B
Alias:
BA1B; Bromodomain adjacent to zinc finger domain, 1B; Transcription factor WSTF; Tyrosine-protein kinase BAZ1B: Bromodomain adjacent to zinc finger domain protein 1B: Williams-Beuren syndrome chromosomal region 9 protein: Williams syndrome transcription factor: Tyrosine-protein kinase BAZ1B: Bromodomain adjacent to zinc finger domain protein 1B: Williams-Beuren syndrome chromosomal region 9 protein: Williams syndrome transcription factor; WALP2; WBRS9; WBSC10; WBSCR10; WBSCR9; Williams syndrome transcription factor; Williams-Beuren syndrome chromosome region 10; Williams-Beuren syndrome chromosome region 9; Williams-Beuren syndrome chromosome region 9 protein; WSTF
Type:
DNA replication; Nuclear receptor co-regulator
Mass (Da):
170903
Number AA:
1483
UniProt ID:
Q9UIG0
International Prot ID:
IPI00069817
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016585
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003682
GO:0070577
PhosphoSite+
KinaseNET
Biological Process:
GO:0016572
GO:0045449
GO:0006974
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
P
G
E
E
P
L
F
T
I
P
H
T
Q
E
A
Site 2
T28
P
L
F
T
I
P
H
T
Q
E
A
F
R
T
R
Site 3
T34
H
T
Q
E
A
F
R
T
R
E
E
Y
E
A
R
Site 4
Y38
A
F
R
T
R
E
E
Y
E
A
R
L
E
R
Y
Site 5
S46
E
A
R
L
E
R
Y
S
E
R
I
W
T
C
K
Site 6
T51
R
Y
S
E
R
I
W
T
C
K
S
T
G
S
S
Site 7
S54
E
R
I
W
T
C
K
S
T
G
S
S
Q
L
T
Site 8
T55
R
I
W
T
C
K
S
T
G
S
S
Q
L
T
H
Site 9
S58
T
C
K
S
T
G
S
S
Q
L
T
H
K
E
A
Site 10
T61
S
T
G
S
S
Q
L
T
H
K
E
A
W
E
E
Site 11
Y114
W
L
E
I
M
T
K
Y
A
V
G
E
E
C
D
Site 12
S152
E
E
A
T
E
K
K
S
D
G
A
C
D
S
P
Site 13
S158
K
S
D
G
A
C
D
S
P
S
S
D
K
E
N
Site 14
S160
D
G
A
C
D
S
P
S
S
D
K
E
N
S
S
Site 15
S161
G
A
C
D
S
P
S
S
D
K
E
N
S
S
Q
Site 16
S166
P
S
S
D
K
E
N
S
S
Q
I
A
Q
D
H
Site 17
S167
S
S
D
K
E
N
S
S
Q
I
A
Q
D
H
Q
Site 18
T178
Q
D
H
Q
K
K
E
T
V
V
K
E
D
E
G
Site 19
S189
E
D
E
G
R
R
E
S
I
N
D
R
A
R
R
Site 20
S197
I
N
D
R
A
R
R
S
P
R
K
L
P
T
S
Site 21
T203
R
S
P
R
K
L
P
T
S
L
K
K
G
E
R
Site 22
S204
S
P
R
K
L
P
T
S
L
K
K
G
E
R
K
Site 23
Y222
P
K
F
L
P
H
K
Y
D
V
K
L
Q
N
E
Site 24
S240
I
S
N
V
P
A
D
S
L
I
R
T
E
R
P
Site 25
T244
P
A
D
S
L
I
R
T
E
R
P
P
N
K
E
Site 26
Y255
P
N
K
E
I
V
R
Y
F
I
R
H
N
A
L
Site 27
T266
H
N
A
L
R
A
G
T
G
E
N
A
P
W
V
Site 28
Y282
E
D
E
L
V
K
K
Y
S
L
P
S
K
F
S
Site 29
S283
D
E
L
V
K
K
Y
S
L
P
S
K
F
S
D
Site 30
S289
Y
S
L
P
S
K
F
S
D
F
L
L
D
P
Y
Site 31
Y296
S
D
F
L
L
D
P
Y
K
Y
M
T
L
N
P
Site 32
Y298
F
L
L
D
P
Y
K
Y
M
T
L
N
P
S
T
Site 33
T300
L
D
P
Y
K
Y
M
T
L
N
P
S
T
K
R
Site 34
T305
Y
M
T
L
N
P
S
T
K
R
K
N
T
G
S
Site 35
T310
P
S
T
K
R
K
N
T
G
S
P
D
R
K
P
Site 36
S312
T
K
R
K
N
T
G
S
P
D
R
K
P
S
K
Site 37
S318
G
S
P
D
R
K
P
S
K
K
S
K
T
D
N
Site 38
S321
D
R
K
P
S
K
K
S
K
T
D
N
S
S
L
Site 39
T323
K
P
S
K
K
S
K
T
D
N
S
S
L
S
S
Site 40
S326
K
K
S
K
T
D
N
S
S
L
S
S
P
L
N
Site 41
S327
K
S
K
T
D
N
S
S
L
S
S
P
L
N
P
Site 42
S329
K
T
D
N
S
S
L
S
S
P
L
N
P
K
L
Site 43
S330
T
D
N
S
S
L
S
S
P
L
N
P
K
L
W
Site 44
S345
C
H
V
H
L
K
K
S
L
S
G
S
P
L
K
Site 45
S347
V
H
L
K
K
S
L
S
G
S
P
L
K
V
K
Site 46
S349
L
K
K
S
L
S
G
S
P
L
K
V
K
N
S
Site 47
S356
S
P
L
K
V
K
N
S
K
N
S
K
S
P
E
Site 48
S359
K
V
K
N
S
K
N
S
K
S
P
E
E
H
L
Site 49
S361
K
N
S
K
N
S
K
S
P
E
E
H
L
E
E
Site 50
S374
E
E
M
M
K
M
M
S
P
N
K
L
H
T
N
Site 51
S417
G
I
L
N
G
Q
K
S
T
G
N
S
K
S
P
Site 52
S421
G
Q
K
S
T
G
N
S
K
S
P
K
K
G
L
Site 53
S423
K
S
T
G
N
S
K
S
P
K
K
G
L
K
T
Site 54
T430
S
P
K
K
G
L
K
T
P
K
T
K
M
K
Q
Site 55
T433
K
G
L
K
T
P
K
T
K
M
K
Q
M
T
L
Site 56
T451
A
K
G
T
Q
K
M
T
R
A
P
R
N
S
G
Site 57
S457
M
T
R
A
P
R
N
S
G
G
T
P
R
T
S
Site 58
T460
A
P
R
N
S
G
G
T
P
R
T
S
S
K
P
Site 59
T463
N
S
G
G
T
P
R
T
S
S
K
P
H
K
H
Site 60
S464
S
G
G
T
P
R
T
S
S
K
P
H
K
H
L
Site 61
S465
G
G
T
P
R
T
S
S
K
P
H
K
H
L
P
Site 62
S493
K
D
R
E
D
K
R
S
A
L
S
C
V
I
S
Site 63
S496
E
D
K
R
S
A
L
S
C
V
I
S
K
T
A
Site 64
S507
S
K
T
A
R
L
L
S
S
E
D
R
A
R
L
Site 65
S508
K
T
A
R
L
L
S
S
E
D
R
A
R
L
P
Site 66
S520
R
L
P
E
E
L
R
S
L
V
Q
K
R
Y
E
Site 67
Y526
R
S
L
V
Q
K
R
Y
E
L
L
E
H
K
K
Site 68
S537
E
H
K
K
R
W
A
S
M
S
E
E
Q
R
K
Site 69
S539
K
K
R
W
A
S
M
S
E
E
Q
R
K
E
Y
Site 70
Y546
S
E
E
Q
R
K
E
Y
L
K
K
K
R
E
E
Site 71
Y580
R
L
E
K
Q
K
R
Y
E
D
Q
E
L
T
G
Site 72
T598
P
A
F
R
L
V
D
T
P
E
G
L
P
N
T
Site 73
Y671
Q
D
E
I
A
E
D
Y
G
E
L
G
M
K
L
Site 74
S699
V
R
L
C
L
R
R
S
D
V
Q
E
E
S
E
Site 75
S705
R
S
D
V
Q
E
E
S
E
G
S
D
T
D
D
Site 76
S708
V
Q
E
E
S
E
G
S
D
T
D
D
N
K
D
Site 77
T710
E
E
S
E
G
S
D
T
D
D
N
K
D
S
A
Site 78
S716
D
T
D
D
N
K
D
S
A
A
F
E
D
N
E
Site 79
T734
E
F
L
E
K
L
E
T
S
E
F
F
E
L
T
Site 80
T759
L
C
H
R
I
L
M
T
Y
S
V
Q
D
H
M
Site 81
Y760
C
H
R
I
L
M
T
Y
S
V
Q
D
H
M
E
Site 82
T818
V
E
N
G
L
G
K
T
D
R
K
K
E
I
V
Site 83
T833
K
F
E
P
Q
V
D
T
E
A
E
D
M
I
S
Site 84
S840
T
E
A
E
D
M
I
S
A
V
K
S
R
R
L
Site 85
S844
D
M
I
S
A
V
K
S
R
R
L
L
A
I
Q
Site 86
T901
A
K
L
V
M
R
R
T
P
I
G
T
D
R
N
Site 87
T905
M
R
R
T
P
I
G
T
D
R
N
H
N
R
Y
Site 88
Y912
T
D
R
N
H
N
R
Y
W
L
F
S
D
E
V
Site 89
S932
E
K
G
W
V
H
D
S
I
D
Y
R
F
N
H
Site 90
Y935
W
V
H
D
S
I
D
Y
R
F
N
H
H
C
K
Site 91
T945
N
H
H
C
K
D
H
T
V
S
G
D
E
D
Y
Site 92
S947
H
C
K
D
H
T
V
S
G
D
E
D
Y
C
P
Site 93
Y952
T
V
S
G
D
E
D
Y
C
P
R
S
K
K
A
Site 94
S956
D
E
D
Y
C
P
R
S
K
K
A
N
L
G
K
Site 95
S966
A
N
L
G
K
N
A
S
M
N
T
Q
H
G
T
Site 96
T983
E
V
A
V
E
T
T
T
P
K
Q
G
Q
N
L
Site 97
S996
N
L
W
F
L
C
D
S
Q
K
E
L
D
E
L
Site 98
S1015
H
P
Q
G
I
R
E
S
Q
L
K
E
R
L
E
Site 99
Y1025
K
E
R
L
E
K
R
Y
Q
D
I
I
H
S
I
Site 100
S1044
K
P
N
L
G
L
K
S
C
D
G
N
Q
E
L
Site 101
Y1073
L
Q
K
G
G
L
G
Y
V
E
E
T
S
E
F
Site 102
S1086
E
F
E
A
R
V
I
S
L
E
K
L
K
D
F
Site 103
S1124
Q
K
R
R
K
L
Q
S
E
D
S
A
K
T
E
Site 104
S1127
R
K
L
Q
S
E
D
S
A
K
T
E
E
V
D
Site 105
S1147
V
E
E
A
K
V
A
S
A
L
E
K
W
K
T
Site 106
T1154
S
A
L
E
K
W
K
T
A
I
R
E
A
Q
T
Site 107
T1161
T
A
I
R
E
A
Q
T
F
S
R
M
H
V
L
Site 108
Y1219
F
C
L
R
P
A
L
Y
E
V
P
D
G
E
W
Site 109
T1235
C
P
A
C
Q
P
A
T
A
R
R
N
S
R
G
Site 110
S1240
P
A
T
A
R
R
N
S
R
G
R
N
Y
T
E
Site 111
Y1245
R
N
S
R
G
R
N
Y
T
E
E
S
A
S
E
Site 112
T1246
N
S
R
G
R
N
Y
T
E
E
S
A
S
E
D
Site 113
S1249
G
R
N
Y
T
E
E
S
A
S
E
D
S
E
D
Site 114
S1251
N
Y
T
E
E
S
A
S
E
D
S
E
D
D
E
Site 115
S1254
E
E
S
A
S
E
D
S
E
D
D
E
S
D
E
Site 116
S1259
E
D
S
E
D
D
E
S
D
E
E
E
E
E
E
Site 117
Y1275
E
E
E
E
E
E
D
Y
E
V
A
G
L
R
L
Site 118
T1287
L
R
L
R
P
R
K
T
I
R
G
K
H
S
V
Site 119
S1293
K
T
I
R
G
K
H
S
V
I
P
P
A
A
R
Site 120
S1301
V
I
P
P
A
A
R
S
G
R
R
P
G
K
K
Site 121
S1311
R
P
G
K
K
P
H
S
T
R
R
S
Q
P
K
Site 122
T1312
P
G
K
K
P
H
S
T
R
R
S
Q
P
K
A
Site 123
S1315
K
P
H
S
T
R
R
S
Q
P
K
A
P
P
V
Site 124
T1334
V
D
E
L
V
L
Q
T
K
R
S
S
R
R
Q
Site 125
S1337
L
V
L
Q
T
K
R
S
S
R
R
Q
S
L
E
Site 126
S1338
V
L
Q
T
K
R
S
S
R
R
Q
S
L
E
L
Site 127
S1342
K
R
S
S
R
R
Q
S
L
E
L
Q
K
C
E
Site 128
Y1358
I
L
H
K
I
V
K
Y
R
F
S
W
P
F
R
Site 129
S1361
K
I
V
K
Y
R
F
S
W
P
F
R
E
P
V
Site 130
Y1376
T
R
D
E
A
E
D
Y
Y
D
V
I
T
H
P
Site 131
Y1377
R
D
E
A
E
D
Y
Y
D
V
I
T
H
P
M
Site 132
S1394
Q
T
V
Q
N
K
C
S
C
G
S
Y
R
S
V
Site 133
S1397
Q
N
K
C
S
C
G
S
Y
R
S
V
Q
E
F
Site 134
Y1398
N
K
C
S
C
G
S
Y
R
S
V
Q
E
F
L
Site 135
S1400
C
S
C
G
S
Y
R
S
V
Q
E
F
L
T
D
Site 136
T1406
R
S
V
Q
E
F
L
T
D
M
K
Q
V
F
T
Site 137
Y1418
V
F
T
N
A
E
V
Y
N
C
R
G
S
H
V
Site 138
Y1449
K
H
L
P
G
H
P
Y
V
R
R
K
R
K
K
Site 139
S1468
L
A
E
D
E
G
D
S
E
P
E
A
V
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation