KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
BAZ2A
Full Name:
ISOFORM 1 OF BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A.
Alias:
BA2A; Bromodomain adjacent to zinc finger domain 2A; Bromodomain adjacent to zinc finger domain, 2A; HWALp3; KIAA0314; TIP5; Transcription termination factor-I interacting protein 5; TTF-I interacting peptide 5; TTF-I interacting protein 5; WALp3
Type:
Transcription regulation
Mass (Da):
211198
Number AA:
1905
UniProt ID:
Q9UIF9
International Prot ID:
IPI00296388
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005677
GO:0005731
GO:0033553
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0070577
PhosphoSite+
KinaseNET
Biological Process:
GO:0006306
GO:0006338
GO:0000183
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
P
P
A
P
A
A
S
G
L
K
P
S
P
S
Site 2
S26
A
A
S
G
L
K
P
S
P
S
S
G
E
G
L
Site 3
S28
S
G
L
K
P
S
P
S
S
G
E
G
L
Y
T
Site 4
S29
G
L
K
P
S
P
S
S
G
E
G
L
Y
T
N
Site 5
Y34
P
S
S
G
E
G
L
Y
T
N
G
S
P
M
N
Site 6
T35
S
S
G
E
G
L
Y
T
N
G
S
P
M
N
F
Site 7
S38
E
G
L
Y
T
N
G
S
P
M
N
F
P
Q
Q
Site 8
S48
N
F
P
Q
Q
G
K
S
L
N
G
D
V
N
V
Site 9
S59
D
V
N
V
N
G
L
S
T
V
S
H
T
T
T
Site 10
T60
V
N
V
N
G
L
S
T
V
S
H
T
T
T
S
Site 11
T66
S
T
V
S
H
T
T
T
S
G
I
L
N
S
A
Site 12
S67
T
V
S
H
T
T
T
S
G
I
L
N
S
A
P
Site 13
S72
T
T
S
G
I
L
N
S
A
P
H
S
S
S
T
Site 14
S76
I
L
N
S
A
P
H
S
S
S
T
S
H
L
H
Site 15
S77
L
N
S
A
P
H
S
S
S
T
S
H
L
H
H
Site 16
S78
N
S
A
P
H
S
S
S
T
S
H
L
H
H
P
Site 17
S80
A
P
H
S
S
S
T
S
H
L
H
H
P
S
V
Site 18
Y95
A
Y
D
C
L
W
N
Y
S
Q
Y
P
S
A
N
Site 19
Y98
C
L
W
N
Y
S
Q
Y
P
S
A
N
P
G
S
Site 20
S100
W
N
Y
S
Q
Y
P
S
A
N
P
G
S
N
L
Site 21
S105
Y
P
S
A
N
P
G
S
N
L
K
D
P
P
L
Site 22
S114
L
K
D
P
P
L
L
S
Q
F
S
G
G
Q
Y
Site 23
S117
P
P
L
L
S
Q
F
S
G
G
Q
Y
P
L
N
Site 24
Y121
S
Q
F
S
G
G
Q
Y
P
L
N
G
I
L
G
Site 25
S130
L
N
G
I
L
G
G
S
R
Q
P
S
S
P
S
Site 26
S134
L
G
G
S
R
Q
P
S
S
P
S
H
N
T
N
Site 27
S135
G
G
S
R
Q
P
S
S
P
S
H
N
T
N
L
Site 28
S137
L
G
G
S
R
Q
P
S
S
P
S
H
N
T
N
Site 29
S146
N
T
N
L
R
A
G
S
Q
E
F
W
A
N
G
Site 30
T154
Q
E
F
W
A
N
G
T
Q
S
P
M
G
L
N
Site 31
S164
P
M
G
L
N
F
D
S
Q
E
L
Y
D
S
F
Site 32
Y168
N
F
D
S
Q
E
L
Y
D
S
F
P
D
Q
N
Site 33
S170
D
S
Q
E
L
Y
D
S
F
P
D
Q
N
F
E
Site 34
S185
V
M
P
N
G
P
P
S
F
F
T
S
P
Q
T
Site 35
S189
G
P
P
S
F
F
T
S
P
Q
T
S
P
M
L
Site 36
T192
S
F
F
T
S
P
Q
T
S
P
M
L
G
S
S
Site 37
S199
T
S
P
M
L
G
S
S
I
Q
T
F
A
P
S
Site 38
S206
S
I
Q
T
F
A
P
S
Q
E
V
G
S
G
I
Site 39
T224
E
A
A
E
K
E
M
T
S
V
V
A
E
N
G
Site 40
S225
A
A
E
K
E
M
T
S
V
V
A
E
N
G
T
Site 41
S237
N
G
T
G
L
V
G
S
L
E
L
E
E
E
Q
Site 42
Y252
P
E
L
K
M
C
G
Y
N
G
S
V
P
S
V
Site 43
S255
K
M
C
G
Y
N
G
S
V
P
S
V
E
S
L
Site 44
S258
G
Y
N
G
S
V
P
S
V
E
S
L
H
Q
E
Site 45
S261
G
S
V
P
S
V
E
S
L
H
Q
E
V
S
V
Site 46
S267
E
S
L
H
Q
E
V
S
V
L
V
P
D
P
T
Site 47
S276
L
V
P
D
P
T
V
S
C
L
D
D
P
S
H
Site 48
S282
V
S
C
L
D
D
P
S
H
L
P
D
Q
L
E
Site 49
T291
L
P
D
Q
L
E
D
T
P
I
L
S
E
D
S
Site 50
S295
L
E
D
T
P
I
L
S
E
D
S
L
E
P
F
Site 51
S298
T
P
I
L
S
E
D
S
L
E
P
F
N
S
L
Site 52
S304
D
S
L
E
P
F
N
S
L
A
P
E
P
V
S
Site 53
Y315
E
P
V
S
G
G
L
Y
G
I
D
D
T
E
L
Site 54
T320
G
L
Y
G
I
D
D
T
E
L
M
G
A
E
D
Site 55
S334
D
K
L
P
L
E
D
S
P
V
I
S
A
L
D
Site 56
S361
L
A
D
D
S
Q
T
S
T
S
I
F
A
S
P
Site 57
T362
A
D
D
S
Q
T
S
T
S
I
F
A
S
P
T
Site 58
S363
D
D
S
Q
T
S
T
S
I
F
A
S
P
T
S
Site 59
S377
S
P
P
V
L
G
E
S
V
L
Q
D
N
S
F
Site 60
S383
E
S
V
L
Q
D
N
S
F
D
L
N
N
G
S
Site 61
S390
S
F
D
L
N
N
G
S
D
A
E
Q
E
E
M
Site 62
T399
A
E
Q
E
E
M
E
T
Q
S
S
D
F
P
P
Site 63
S402
E
E
M
E
T
Q
S
S
D
F
P
P
S
L
T
Site 64
S407
Q
S
S
D
F
P
P
S
L
T
Q
P
A
P
D
Site 65
T409
S
D
F
P
P
S
L
T
Q
P
A
P
D
Q
S
Site 66
S416
T
Q
P
A
P
D
Q
S
S
T
I
Q
L
H
P
Site 67
S426
I
Q
L
H
P
A
T
S
P
A
V
S
P
T
T
Site 68
S430
P
A
T
S
P
A
V
S
P
T
T
S
P
A
V
Site 69
S492
P
L
T
A
S
V
T
S
P
K
A
S
P
V
T
Site 70
S496
S
V
T
S
P
K
A
S
P
V
T
S
P
A
A
Site 71
S500
P
K
A
S
P
V
T
S
P
A
A
A
F
P
T
Site 72
T507
S
P
A
A
A
F
P
T
A
S
P
A
N
K
D
Site 73
S509
A
A
A
F
P
T
A
S
P
A
N
K
D
V
S
Site 74
S516
S
P
A
N
K
D
V
S
S
F
L
E
T
T
A
Site 75
S517
P
A
N
K
D
V
S
S
F
L
E
T
T
A
D
Site 76
T521
V
M
R
R
R
I
A
T
P
E
E
V
R
L
P
Site 77
T534
E
I
T
G
E
G
L
T
A
S
G
S
G
D
V
Site 78
S536
T
G
E
G
L
T
A
S
G
S
G
D
V
M
R
Site 79
S538
E
G
L
T
A
S
G
S
G
D
V
M
R
R
R
Site 80
T548
V
M
R
R
R
I
A
T
P
E
E
V
R
L
P
Site 81
S570
E
V
R
I
K
K
G
S
H
R
W
Q
G
E
T
Site 82
Y579
R
W
Q
G
E
T
W
Y
Y
G
P
C
G
K
R
Site 83
Y596
Q
F
P
E
V
I
K
Y
L
S
R
N
V
V
H
Site 84
S598
P
E
V
I
K
Y
L
S
R
N
V
V
H
S
V
Site 85
S604
L
S
R
N
V
V
H
S
V
R
R
E
H
F
S
Site 86
S611
S
V
R
R
E
H
F
S
F
S
P
R
M
P
V
Site 87
S613
R
R
E
H
F
S
F
S
P
R
M
P
V
G
D
Site 88
T627
D
F
F
E
E
R
D
T
P
E
G
L
Q
W
V
Site 89
S637
G
L
Q
W
V
Q
L
S
A
E
E
I
P
S
R
Site 90
T649
P
S
R
I
Q
A
I
T
G
K
R
G
R
P
R
Site 91
T658
K
R
G
R
P
R
N
T
E
K
A
K
T
K
E
Site 92
T663
R
N
T
E
K
A
K
T
K
E
V
P
K
V
K
Site 93
T688
I
T
E
L
L
N
K
T
D
N
R
P
L
K
K
Site 94
T701
K
K
L
E
A
Q
E
T
L
N
E
E
D
K
A
Site 95
S713
D
K
A
K
I
A
K
S
K
K
K
M
R
Q
K
Site 96
T728
V
Q
R
G
E
C
Q
T
T
I
Q
G
Q
A
R
Site 97
T729
Q
R
G
E
C
Q
T
T
I
Q
G
Q
A
R
N
Site 98
S744
K
R
K
Q
E
T
K
S
L
K
Q
K
E
A
K
Site 99
S754
Q
K
E
A
K
K
K
S
K
A
E
K
E
K
G
Site 100
T763
A
E
K
E
K
G
K
T
K
Q
E
K
L
K
E
Site 101
T800
P
A
C
K
A
D
K
T
L
A
T
Q
R
R
L
Site 102
T803
K
A
D
K
T
L
A
T
Q
R
R
L
E
E
R
Site 103
T830
P
T
E
D
M
C
L
T
D
H
Q
P
L
P
D
Site 104
S839
H
Q
P
L
P
D
F
S
R
V
P
G
L
T
L
Site 105
S878
D
P
A
K
D
V
P
S
L
G
V
L
Q
E
G
Site 106
S915
L
H
D
P
G
F
P
S
Y
C
Q
S
L
K
I
Site 107
Y916
H
D
P
G
F
P
S
Y
C
Q
S
L
K
I
L
Site 108
S919
G
F
P
S
Y
C
Q
S
L
K
I
L
G
E
K
Site 109
S928
K
I
L
G
E
K
V
S
E
I
P
L
T
R
D
Site 110
T933
K
V
S
E
I
P
L
T
R
D
N
V
S
E
I
Site 111
T960
A
L
C
D
R
L
R
T
Q
P
F
Q
A
Q
P
Site 112
T995
I
I
N
E
I
D
K
T
L
E
S
M
S
S
Y
Site 113
S998
E
I
D
K
T
L
E
S
M
S
S
Y
R
K
N
Site 114
S1000
D
K
T
L
E
S
M
S
S
Y
R
K
N
K
W
Site 115
S1001
K
T
L
E
S
M
S
S
Y
R
K
N
K
W
I
Site 116
Y1002
T
L
E
S
M
S
S
Y
R
K
N
K
W
I
V
Site 117
T1018
G
R
L
R
R
L
K
T
V
L
A
K
R
T
G
Site 118
S1043
E
C
L
G
R
R
R
S
S
R
I
M
E
E
T
Site 119
S1044
C
L
G
R
R
R
S
S
R
I
M
E
E
T
S
Site 120
T1050
S
S
R
I
M
E
E
T
S
G
M
E
E
E
E
Site 121
S1051
S
R
I
M
E
E
T
S
G
M
E
E
E
E
E
Site 122
S1061
E
E
E
E
E
E
E
S
I
A
A
V
P
G
R
Site 123
T1079
R
D
G
E
V
D
A
T
A
S
S
I
P
E
L
Site 124
S1082
E
V
D
A
T
A
S
S
I
P
E
L
E
R
Q
Site 125
S1094
E
R
Q
I
E
K
L
S
K
R
Q
L
F
F
R
Site 126
S1108
R
K
K
L
L
H
S
S
Q
M
L
R
A
V
S
Site 127
S1115
S
Q
M
L
R
A
V
S
L
G
Q
D
R
Y
R
Site 128
Y1121
V
S
L
G
Q
D
R
Y
R
R
R
Y
W
V
L
Site 129
Y1125
Q
D
R
Y
R
R
R
Y
W
V
L
P
Y
L
A
Site 130
S1155
V
I
K
K
E
T
D
S
L
K
V
A
A
H
A
Site 131
S1178
M
K
M
E
L
A
G
S
N
T
T
A
S
S
P
Site 132
T1180
M
E
L
A
G
S
N
T
T
A
S
S
P
A
R
Site 133
S1183
A
G
S
N
T
T
A
S
S
P
A
R
A
R
G
Site 134
S1184
G
S
N
T
T
A
S
S
P
A
R
A
R
G
R
Site 135
T1195
A
R
G
R
P
R
K
T
K
P
G
S
M
Q
P
Site 136
S1199
P
R
K
T
K
P
G
S
M
Q
P
R
H
L
K
Site 137
S1207
M
Q
P
R
H
L
K
S
P
V
R
G
Q
D
S
Site 138
S1214
S
P
V
R
G
Q
D
S
E
Q
P
Q
A
Q
L
Site 139
S1243
Q
L
Q
L
Q
L
Q
S
H
K
G
F
L
E
Q
Site 140
S1253
G
F
L
E
Q
E
G
S
P
L
S
L
G
Q
S
Site 141
S1256
E
Q
E
G
S
P
L
S
L
G
Q
S
Q
H
D
Site 142
S1260
S
P
L
S
L
G
Q
S
Q
H
D
L
S
Q
S
Site 143
S1265
G
Q
S
Q
H
D
L
S
Q
S
A
F
L
S
W
Site 144
S1267
S
Q
H
D
L
S
Q
S
A
F
L
S
W
L
S
Site 145
S1271
L
S
Q
S
A
F
L
S
W
L
S
Q
T
Q
S
Site 146
S1274
S
A
F
L
S
W
L
S
Q
T
Q
S
H
S
S
Site 147
T1276
F
L
S
W
L
S
Q
T
Q
S
H
S
S
L
L
Site 148
S1278
S
W
L
S
Q
T
Q
S
H
S
S
L
L
S
S
Site 149
S1280
L
S
Q
T
Q
S
H
S
S
L
L
S
S
S
V
Site 150
S1281
S
Q
T
Q
S
H
S
S
L
L
S
S
S
V
L
Site 151
S1284
Q
S
H
S
S
L
L
S
S
S
V
L
T
P
D
Site 152
S1285
S
H
S
S
L
L
S
S
S
V
L
T
P
D
S
Site 153
S1286
H
S
S
L
L
S
S
S
V
L
T
P
D
S
S
Site 154
T1289
L
L
S
S
S
V
L
T
P
D
S
S
P
G
K
Site 155
S1292
S
S
V
L
T
P
D
S
S
P
G
K
L
D
P
Site 156
S1293
S
V
L
T
P
D
S
S
P
G
K
L
D
P
A
Site 157
S1302
G
K
L
D
P
A
P
S
Q
P
P
E
E
P
E
Site 158
S1316
E
P
D
E
A
E
S
S
P
D
P
Q
A
L
W
Site 159
T1337
M
P
C
N
A
A
P
T
P
P
P
A
V
S
E
Site 160
S1343
P
T
P
P
P
A
V
S
E
D
Q
P
T
P
S
Site 161
T1348
A
V
S
E
D
Q
P
T
P
S
P
Q
Q
L
A
Site 162
S1350
S
E
D
Q
P
T
P
S
P
Q
Q
L
A
S
S
Site 163
S1356
P
S
P
Q
Q
L
A
S
S
K
P
M
N
R
P
Site 164
S1357
S
P
Q
Q
L
A
S
S
K
P
M
N
R
P
S
Site 165
S1364
S
K
P
M
N
R
P
S
A
A
N
P
C
S
P
Site 166
S1370
D
P
G
E
M
P
Q
S
P
T
G
L
G
Q
P
Site 167
S1376
C
S
P
V
Q
F
S
S
T
P
L
A
G
L
A
Site 168
T1377
S
P
V
Q
F
S
S
T
P
L
A
G
L
A
P
Site 169
S1397
D
P
G
E
M
P
Q
S
P
T
G
L
G
Q
P
Site 170
T1399
G
E
M
P
Q
S
P
T
G
L
G
Q
P
K
R
Site 171
S1412
K
R
R
G
R
P
P
S
K
F
F
K
Q
M
E
Site 172
T1424
Q
M
E
Q
R
Y
L
T
Q
L
T
A
Q
P
V
Site 173
T1427
Q
R
Y
L
T
Q
L
T
A
Q
P
V
P
P
E
Site 174
S1484
Q
E
V
C
L
R
P
S
A
D
P
I
F
E
P
Site 175
S1503
A
F
Q
E
G
I
M
S
W
S
P
K
E
K
T
Site 176
S1505
Q
E
G
I
M
S
W
S
P
K
E
K
T
Y
E
Site 177
T1510
S
W
S
P
K
E
K
T
Y
E
T
D
L
A
V
Site 178
T1539
D
L
Q
I
R
G
W
T
C
P
S
P
D
S
T
Site 179
S1542
I
R
G
W
T
C
P
S
P
D
S
T
R
E
D
Site 180
S1545
W
T
C
P
S
P
D
S
T
R
E
D
L
A
Y
Site 181
T1546
T
C
P
S
P
D
S
T
R
E
D
L
A
Y
C
Site 182
Y1552
S
T
R
E
D
L
A
Y
C
E
H
L
S
D
S
Site 183
S1557
L
A
Y
C
E
H
L
S
D
S
Q
E
D
I
T
Site 184
S1559
Y
C
E
H
L
S
D
S
Q
E
D
I
T
W
R
Site 185
T1564
S
D
S
Q
E
D
I
T
W
R
G
R
G
R
E
Site 186
T1579
G
L
A
P
Q
R
K
T
T
N
P
L
D
L
A
Site 187
T1580
L
A
P
Q
R
K
T
T
N
P
L
D
L
A
V
Site 188
Y1601
E
Q
N
V
E
R
R
Y
L
R
E
P
L
W
P
Site 189
S1620
V
L
E
K
A
L
L
S
T
P
N
G
A
P
E
Site 190
T1621
L
E
K
A
L
L
S
T
P
N
G
A
P
E
G
Site 191
T1631
G
A
P
E
G
T
T
T
E
I
S
Y
E
I
T
Site 192
S1634
E
G
T
T
T
E
I
S
Y
E
I
T
P
R
I
Site 193
T1638
T
E
I
S
Y
E
I
T
P
R
I
R
V
W
R
Site 194
T1647
R
I
R
V
W
R
Q
T
L
E
R
C
R
S
A
Site 195
S1667
C
L
G
Q
L
E
R
S
I
A
W
E
K
S
V
Site 196
S1673
R
S
I
A
W
E
K
S
V
N
K
V
T
C
L
Site 197
T1733
Q
Q
V
E
G
E
F
T
Q
K
P
G
F
P
K
Site 198
S1747
K
R
G
Q
K
R
K
S
G
Y
S
L
N
F
S
Site 199
S1750
Q
K
R
K
S
G
Y
S
L
N
F
S
E
G
D
Site 200
S1754
S
G
Y
S
L
N
F
S
E
G
D
G
R
R
R
Site 201
S1770
V
L
L
R
G
R
E
S
P
A
A
G
P
R
Y
Site 202
Y1777
S
P
A
A
G
P
R
Y
S
E
E
G
L
S
P
Site 203
S1778
P
A
A
G
P
R
Y
S
E
E
G
L
S
P
S
Site 204
S1783
R
Y
S
E
E
G
L
S
P
S
K
R
R
R
L
Site 205
S1785
S
E
E
G
L
S
P
S
K
R
R
R
L
S
M
Site 206
S1791
P
S
K
R
R
R
L
S
M
R
N
H
H
S
D
Site 207
S1828
P
V
N
P
R
L
V
S
G
Y
R
R
I
I
K
Site 208
Y1830
N
P
R
L
V
S
G
Y
R
R
I
I
K
N
P
Site 209
S1841
I
K
N
P
M
D
F
S
T
M
R
E
R
L
L
Site 210
T1842
K
N
P
M
D
F
S
T
M
R
E
R
L
L
R
Site 211
Y1852
E
R
L
L
R
G
G
Y
T
S
S
E
E
F
A
Site 212
S1854
L
L
R
G
G
Y
T
S
S
E
E
F
A
A
D
Site 213
S1855
L
R
G
G
Y
T
S
S
E
E
F
A
A
D
A
Site 214
S1877
Q
T
F
N
E
D
D
S
E
V
G
K
A
G
H
Site 215
Y1898
E
S
R
W
E
E
F
Y
Q
G
K
Q
A
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation