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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BAZ2B
Full Name:
Bromodomain adjacent to zinc finger domain protein 2B
Alias:
bromodomain adjacent to zinc finger domain 2B; bromodomain adjacent to zinc finger domain, 2B; WALp4
Type:
Unknown function
Mass (Da):
220710
Number AA:
1972
UniProt ID:
Q9UIF8
International Prot ID:
IPI00747713
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
S
G
E
R
L
P
S
S
A
A
S
S
T
T
Site 2
S10
S
G
E
R
L
P
S
S
A
A
S
S
T
T
P
Site 3
S13
R
L
P
S
S
A
A
S
S
T
T
P
T
S
S
Site 4
S14
L
P
S
S
A
A
S
S
T
T
P
T
S
S
S
Site 5
T15
P
S
S
A
A
S
S
T
T
P
T
S
S
S
T
Site 6
T16
S
S
A
A
S
S
T
T
P
T
S
S
S
T
P
Site 7
T18
A
A
S
S
T
T
P
T
S
S
S
T
P
S
V
Site 8
S19
A
S
S
T
T
P
T
S
S
S
T
P
S
V
A
Site 9
S20
S
S
T
T
P
T
S
S
S
T
P
S
V
A
S
Site 10
S21
S
T
T
P
T
S
S
S
T
P
S
V
A
S
V
Site 11
T22
T
T
P
T
S
S
S
T
P
S
V
A
S
V
V
Site 12
S24
P
T
S
S
S
T
P
S
V
A
S
V
V
S
K
Site 13
T54
P
C
G
H
L
F
R
T
A
G
D
Q
P
F
N
Site 14
S63
G
D
Q
P
F
N
L
S
T
V
S
S
A
F
P
Site 15
T64
D
Q
P
F
N
L
S
T
V
S
S
A
F
P
M
Site 16
S81
H
P
V
F
G
L
H
S
A
S
S
G
H
S
E
Site 17
S83
V
F
G
L
H
S
A
S
S
G
H
S
E
F
G
Site 18
S84
F
G
L
H
S
A
S
S
G
H
S
E
F
G
G
Site 19
S87
H
S
A
S
S
G
H
S
E
F
G
G
L
G
T
Site 20
S109
A
A
H
P
Q
L
A
S
F
P
G
A
E
W
W
Site 21
S149
P
P
A
Q
N
H
D
S
S
S
F
H
S
R
T
Site 22
S150
P
A
Q
N
H
D
S
S
S
F
H
S
R
T
S
Site 23
S151
A
Q
N
H
D
S
S
S
F
H
S
R
T
S
G
Site 24
S154
H
D
S
S
S
F
H
S
R
T
S
G
K
S
N
Site 25
T156
S
S
S
F
H
S
R
T
S
G
K
S
N
R
N
Site 26
S157
S
S
F
H
S
R
T
S
G
K
S
N
R
N
G
Site 27
S160
H
S
R
T
S
G
K
S
N
R
N
G
P
E
K
Site 28
S172
P
E
K
G
V
N
G
S
I
N
G
S
N
T
S
Site 29
S176
V
N
G
S
I
N
G
S
N
T
S
S
V
I
G
Site 30
T178
G
S
I
N
G
S
N
T
S
S
V
I
G
I
N
Site 31
S179
S
I
N
G
S
N
T
S
S
V
I
G
I
N
T
Site 32
S180
I
N
G
S
N
T
S
S
V
I
G
I
N
T
S
Site 33
T192
N
T
S
V
L
S
T
T
A
S
S
S
M
G
Q
Site 34
S194
S
V
L
S
T
T
A
S
S
S
M
G
Q
T
K
Site 35
S196
L
S
T
T
A
S
S
S
M
G
Q
T
K
S
T
Site 36
T200
A
S
S
S
M
G
Q
T
K
S
T
S
S
G
G
Site 37
S202
S
S
M
G
Q
T
K
S
T
S
S
G
G
G
N
Site 38
T203
S
M
G
Q
T
K
S
T
S
S
G
G
G
N
R
Site 39
S204
M
G
Q
T
K
S
T
S
S
G
G
G
N
R
K
Site 40
S241
P
R
K
K
A
M
E
S
S
S
N
S
D
S
D
Site 41
S242
R
K
K
A
M
E
S
S
S
N
S
D
S
D
S
Site 42
S243
K
K
A
M
E
S
S
S
N
S
D
S
D
S
G
Site 43
S245
A
M
E
S
S
S
N
S
D
S
D
S
G
T
S
Site 44
S247
E
S
S
S
N
S
D
S
D
S
G
T
S
S
D
Site 45
S249
S
S
N
S
D
S
D
S
G
T
S
S
D
T
S
Site 46
T251
N
S
D
S
D
S
G
T
S
S
D
T
S
S
E
Site 47
S252
S
D
S
D
S
G
T
S
S
D
T
S
S
E
G
Site 48
S253
D
S
D
S
G
T
S
S
D
T
S
S
E
G
I
Site 49
T255
D
S
G
T
S
S
D
T
S
S
E
G
I
S
S
Site 50
S256
S
G
T
S
S
D
T
S
S
E
G
I
S
S
S
Site 51
S257
G
T
S
S
D
T
S
S
E
G
I
S
S
S
D
Site 52
S261
D
T
S
S
E
G
I
S
S
S
D
S
D
D
L
Site 53
S262
T
S
S
E
G
I
S
S
S
D
S
D
D
L
E
Site 54
S263
S
S
E
G
I
S
S
S
D
S
D
D
L
E
E
Site 55
S265
E
G
I
S
S
S
D
S
D
D
L
E
E
D
E
Site 56
S278
D
E
E
E
E
D
Q
S
I
E
E
S
E
D
D
Site 57
S282
E
D
Q
S
I
E
E
S
E
D
D
D
S
D
S
Site 58
S287
E
E
S
E
D
D
D
S
D
S
E
S
E
A
Q
Site 59
S289
S
E
D
D
D
S
D
S
E
S
E
A
Q
H
K
Site 60
S291
D
D
D
S
D
S
E
S
E
A
Q
H
K
S
N
Site 61
S297
E
S
E
A
Q
H
K
S
N
N
Q
V
L
L
H
Site 62
S307
Q
V
L
L
H
G
I
S
D
P
K
A
D
G
Q
Site 63
S333
H
Q
P
L
P
L
A
S
E
S
Q
T
H
S
F
Site 64
S335
P
L
P
L
A
S
E
S
Q
T
H
S
F
Q
S
Site 65
T337
P
L
A
S
E
S
Q
T
H
S
F
Q
S
Q
Q
Site 66
S339
A
S
E
S
Q
T
H
S
F
Q
S
Q
Q
K
Q
Site 67
S342
S
Q
T
H
S
F
Q
S
Q
Q
K
Q
P
Q
V
Site 68
S351
Q
K
Q
P
Q
V
L
S
Q
Q
L
P
F
I
F
Site 69
S361
L
P
F
I
F
Q
S
S
Q
A
K
E
E
S
V
Site 70
S367
S
S
Q
A
K
E
E
S
V
N
K
H
T
S
V
Site 71
T372
E
E
S
V
N
K
H
T
S
V
I
Q
S
T
G
Site 72
S373
E
S
V
N
K
H
T
S
V
I
Q
S
T
G
L
Site 73
S377
K
H
T
S
V
I
Q
S
T
G
L
V
S
N
V
Site 74
S388
V
S
N
V
K
P
L
S
L
V
N
Q
A
K
K
Site 75
Y398
N
Q
A
K
K
E
T
Y
M
K
L
I
V
P
S
Site 76
T416
L
K
A
G
N
K
N
T
S
E
E
S
S
L
L
Site 77
S417
K
A
G
N
K
N
T
S
E
E
S
S
L
L
T
Site 78
S421
K
N
T
S
E
E
S
S
L
L
T
S
E
L
R
Site 79
T424
S
E
E
S
S
L
L
T
S
E
L
R
S
K
R
Site 80
S425
E
E
S
S
L
L
T
S
E
L
R
S
K
R
E
Site 81
S429
L
L
T
S
E
L
R
S
K
R
E
Q
Y
K
Q
Site 82
Y434
L
R
S
K
R
E
Q
Y
K
Q
A
F
P
S
Q
Site 83
S440
Q
Y
K
Q
A
F
P
S
Q
L
K
K
Q
E
S
Site 84
S447
S
Q
L
K
K
Q
E
S
S
K
S
L
K
K
V
Site 85
S448
Q
L
K
K
Q
E
S
S
K
S
L
K
K
V
I
Site 86
S450
K
K
Q
E
S
S
K
S
L
K
K
V
I
A
A
Site 87
S459
K
K
V
I
A
A
L
S
N
P
K
A
T
S
S
Site 88
T464
A
L
S
N
P
K
A
T
S
S
S
P
A
H
P
Site 89
S465
L
S
N
P
K
A
T
S
S
S
P
A
H
P
K
Site 90
S466
S
N
P
K
A
T
S
S
S
P
A
H
P
K
Q
Site 91
S467
N
P
K
A
T
S
S
S
P
A
H
P
K
Q
T
Site 92
T485
N
H
P
N
P
F
L
T
N
A
L
L
G
N
H
Site 93
S500
Q
P
N
G
V
I
Q
S
V
I
Q
E
A
P
L
Site 94
T513
P
L
A
L
T
T
K
T
K
M
Q
S
K
I
N
Site 95
S527
N
E
N
I
A
A
A
S
S
T
P
F
S
S
P
Site 96
S528
E
N
I
A
A
A
S
S
T
P
F
S
S
P
V
Site 97
T529
N
I
A
A
A
S
S
T
P
F
S
S
P
V
N
Site 98
S532
A
A
S
S
T
P
F
S
S
P
V
N
L
S
T
Site 99
S533
A
S
S
T
P
F
S
S
P
V
N
L
S
T
S
Site 100
S538
F
S
S
P
V
N
L
S
T
S
G
R
R
T
P
Site 101
T539
S
S
P
V
N
L
S
T
S
G
R
R
T
P
G
Site 102
S540
S
P
V
N
L
S
T
S
G
R
R
T
P
G
N
Site 103
T544
L
S
T
S
G
R
R
T
P
G
N
Q
T
P
V
Site 104
T549
R
R
T
P
G
N
Q
T
P
V
M
P
S
A
S
Site 105
S554
N
Q
T
P
V
M
P
S
A
S
P
I
L
H
S
Site 106
S556
T
P
V
M
P
S
A
S
P
I
L
H
S
Q
G
Site 107
S561
S
A
S
P
I
L
H
S
Q
G
K
E
K
A
V
Site 108
S569
Q
G
K
E
K
A
V
S
N
N
V
N
P
V
K
Site 109
T577
N
N
V
N
P
V
K
T
Q
H
H
S
H
P
A
Site 110
S581
P
V
K
T
Q
H
H
S
H
P
A
K
S
L
V
Site 111
S586
H
H
S
H
P
A
K
S
L
V
E
Q
F
R
G
Site 112
T594
L
V
E
Q
F
R
G
T
D
S
D
I
P
S
S
Site 113
S596
E
Q
F
R
G
T
D
S
D
I
P
S
S
K
D
Site 114
S600
G
T
D
S
D
I
P
S
S
K
D
S
E
D
S
Site 115
S601
T
D
S
D
I
P
S
S
K
D
S
E
D
S
N
Site 116
S604
D
I
P
S
S
K
D
S
E
D
S
N
E
D
E
Site 117
S607
S
S
K
D
S
E
D
S
N
E
D
E
E
E
D
Site 118
S628
E
D
D
E
D
D
E
S
D
D
S
Q
S
E
S
Site 119
S631
E
D
D
E
S
D
D
S
Q
S
E
S
D
S
N
Site 120
S633
D
E
S
D
D
S
Q
S
E
S
D
S
N
S
E
Site 121
S635
S
D
D
S
Q
S
E
S
D
S
N
S
E
S
D
Site 122
S637
D
S
Q
S
E
S
D
S
N
S
E
S
D
T
E
Site 123
S639
Q
S
E
S
D
S
N
S
E
S
D
T
E
G
S
Site 124
S641
E
S
D
S
N
S
E
S
D
T
E
G
S
E
E
Site 125
T643
D
S
N
S
E
S
D
T
E
G
S
E
E
E
D
Site 126
S659
D
D
K
D
Q
D
E
S
D
S
D
T
E
G
E
Site 127
S661
K
D
Q
D
E
S
D
S
D
T
E
G
E
K
T
Site 128
T663
Q
D
E
S
D
S
D
T
E
G
E
K
T
S
M
Site 129
T668
S
D
T
E
G
E
K
T
S
M
K
L
N
K
T
Site 130
T675
T
S
M
K
L
N
K
T
T
S
S
V
K
S
P
Site 131
T676
S
M
K
L
N
K
T
T
S
S
V
K
S
P
S
Site 132
S677
M
K
L
N
K
T
T
S
S
V
K
S
P
S
M
Site 133
S678
K
L
N
K
T
T
S
S
V
K
S
P
S
M
S
Site 134
S681
K
T
T
S
S
V
K
S
P
S
M
S
L
T
G
Site 135
S683
T
S
S
V
K
S
P
S
M
S
L
T
G
H
S
Site 136
S685
S
V
K
S
P
S
M
S
L
T
G
H
S
T
P
Site 137
T687
K
S
P
S
M
S
L
T
G
H
S
T
P
R
N
Site 138
S690
S
M
S
L
T
G
H
S
T
P
R
N
L
H
I
Site 139
T691
M
S
L
T
G
H
S
T
P
R
N
L
H
I
A
Site 140
S710
S
A
P
A
A
L
C
S
E
S
Q
S
P
A
F
Site 141
S714
A
L
C
S
E
S
Q
S
P
A
F
L
G
T
S
Site 142
T720
Q
S
P
A
F
L
G
T
S
S
S
T
L
T
S
Site 143
S721
S
P
A
F
L
G
T
S
S
S
T
L
T
S
S
Site 144
S722
P
A
F
L
G
T
S
S
S
T
L
T
S
S
P
Site 145
S723
A
F
L
G
T
S
S
S
T
L
T
S
S
P
H
Site 146
T724
F
L
G
T
S
S
S
T
L
T
S
S
P
H
S
Site 147
T726
G
T
S
S
S
T
L
T
S
S
P
H
S
G
T
Site 148
S727
T
S
S
S
T
L
T
S
S
P
H
S
G
T
S
Site 149
S728
S
S
S
T
L
T
S
S
P
H
S
G
T
S
K
Site 150
S731
T
L
T
S
S
P
H
S
G
T
S
K
R
R
R
Site 151
S734
S
S
P
H
S
G
T
S
K
R
R
R
V
T
D
Site 152
T740
T
S
K
R
R
R
V
T
D
E
R
E
L
R
I
Site 153
Y751
E
L
R
I
P
L
E
Y
G
W
Q
R
E
T
R
Site 154
Y772
R
L
Q
G
E
V
A
Y
Y
A
P
C
G
K
K
Site 155
Y773
L
Q
G
E
V
A
Y
Y
A
P
C
G
K
K
L
Site 156
Y783
C
G
K
K
L
R
Q
Y
P
E
V
I
K
Y
L
Site 157
Y789
Q
Y
P
E
V
I
K
Y
L
S
R
N
G
I
M
Site 158
S799
R
N
G
I
M
D
I
S
R
D
N
F
S
F
S
Site 159
S804
D
I
S
R
D
N
F
S
F
S
A
K
I
R
V
Site 160
S806
S
R
D
N
F
S
F
S
A
K
I
R
V
G
D
Site 161
Y815
K
I
R
V
G
D
F
Y
E
A
R
D
G
P
Q
Site 162
S860
R
Q
R
A
R
E
E
S
R
M
R
R
R
K
G
Site 163
T1089
G
L
V
L
S
G
S
T
F
S
D
C
L
M
V
Site 164
S1196
G
Q
T
E
L
T
E
S
L
K
T
K
A
F
Q
Site 165
T1199
E
L
T
E
S
L
K
T
K
A
F
Q
A
H
T
Site 166
T1206
T
K
A
F
Q
A
H
T
P
A
Q
K
A
S
V
Site 167
S1226
N
E
L
A
C
S
K
S
V
V
S
E
I
D
K
Site 168
Y1237
E
I
D
K
N
I
D
Y
M
S
N
L
R
R
D
Site 169
T1263
R
I
I
H
A
K
K
T
G
K
R
D
T
S
G
Site 170
T1268
K
K
T
G
K
R
D
T
S
G
G
I
D
L
G
Site 171
S1269
K
T
G
K
R
D
T
S
G
G
I
D
L
G
E
Site 172
T1283
E
E
Q
H
P
L
G
T
P
T
P
G
R
K
R
Site 173
T1285
Q
H
P
L
G
T
P
T
P
G
R
K
R
R
R
Site 174
S1297
R
R
R
K
G
G
D
S
D
Y
D
D
D
D
D
Site 175
Y1299
R
K
G
G
D
S
D
Y
D
D
D
D
D
D
D
Site 176
S1307
D
D
D
D
D
D
D
S
D
D
Q
G
D
E
D
Site 177
S1343
D
E
G
D
Q
A
A
S
V
E
E
L
E
K
Q
Site 178
S1355
E
K
Q
I
E
K
L
S
K
Q
Q
S
Q
Y
R
Site 179
S1359
E
K
L
S
K
Q
Q
S
Q
Y
R
R
K
L
F
Site 180
S1369
R
R
K
L
F
D
A
S
H
S
L
R
S
V
M
Site 181
S1374
D
A
S
H
S
L
R
S
V
M
F
G
Q
D
R
Site 182
Y1382
V
M
F
G
Q
D
R
Y
R
R
R
Y
W
I
L
Site 183
Y1386
Q
D
R
Y
R
R
R
Y
W
I
L
P
Q
C
G
Site 184
S1421
E
K
L
K
K
A
E
S
V
Q
I
K
E
E
M
Site 185
T1431
I
K
E
E
M
F
E
T
S
G
D
S
L
N
C
Site 186
S1432
K
E
E
M
F
E
T
S
G
D
S
L
N
C
S
Site 187
S1435
M
F
E
T
S
G
D
S
L
N
C
S
N
T
D
Site 188
S1439
S
G
D
S
L
N
C
S
N
T
D
H
C
E
Q
Site 189
T1456
D
L
K
E
K
D
N
T
N
L
F
L
Q
K
P
Site 190
S1465
L
F
L
Q
K
P
G
S
F
S
K
L
S
K
L
Site 191
S1482
V
A
K
M
P
P
E
S
E
V
M
T
P
K
P
Site 192
T1486
P
P
E
S
E
V
M
T
P
K
P
N
A
G
A
Site 193
S1499
G
A
N
G
C
T
L
S
Y
Q
N
S
G
K
H
Site 194
Y1500
A
N
G
C
T
L
S
Y
Q
N
S
G
K
H
S
Site 195
S1503
C
T
L
S
Y
Q
N
S
G
K
H
S
L
G
S
Site 196
S1507
Y
Q
N
S
G
K
H
S
L
G
S
V
Q
S
T
Site 197
S1510
S
G
K
H
S
L
G
S
V
Q
S
T
A
T
Q
Site 198
S1513
H
S
L
G
S
V
Q
S
T
A
T
Q
S
N
V
Site 199
T1514
S
L
G
S
V
Q
S
T
A
T
Q
S
N
V
E
Site 200
S1525
S
N
V
E
K
A
D
S
N
N
L
F
N
T
G
Site 201
T1531
D
S
N
N
L
F
N
T
G
S
S
G
P
G
K
Site 202
S1533
N
N
L
F
N
T
G
S
S
G
P
G
K
F
Y
Site 203
S1541
S
G
P
G
K
F
Y
S
P
L
P
N
D
Q
L
Site 204
T1551
P
N
D
Q
L
L
K
T
L
T
E
K
N
R
Q
Site 205
T1553
D
Q
L
L
K
T
L
T
E
K
N
R
Q
W
F
Site 206
S1561
E
K
N
R
Q
W
F
S
L
L
P
R
T
P
C
Site 207
T1566
W
F
S
L
L
P
R
T
P
C
D
D
T
S
L
Site 208
T1571
P
R
T
P
C
D
D
T
S
L
T
H
A
D
M
Site 209
S1572
R
T
P
C
D
D
T
S
L
T
H
A
D
M
S
Site 210
T1574
P
C
D
D
T
S
L
T
H
A
D
M
S
T
A
Site 211
S1582
H
A
D
M
S
T
A
S
L
V
T
P
Q
S
Q
Site 212
T1585
M
S
T
A
S
L
V
T
P
Q
S
Q
P
P
S
Site 213
S1588
A
S
L
V
T
P
Q
S
Q
P
P
S
K
S
P
Site 214
S1592
T
P
Q
S
Q
P
P
S
K
S
P
S
P
T
P
Site 215
S1594
Q
S
Q
P
P
S
K
S
P
S
P
T
P
A
P
Site 216
S1596
Q
P
P
S
K
S
P
S
P
T
P
A
P
L
G
Site 217
T1598
P
S
K
S
P
S
P
T
P
A
P
L
G
S
S
Site 218
S1604
P
T
P
A
P
L
G
S
S
A
Q
N
P
V
G
Site 219
S1618
G
L
N
P
F
A
L
S
P
L
Q
V
K
G
G
Site 220
S1649
T
S
N
I
P
F
T
S
S
V
P
S
L
G
S
Site 221
S1650
S
N
I
P
F
T
S
S
V
P
S
L
G
S
G
Site 222
S1661
L
G
S
G
L
G
L
S
E
G
N
G
N
S
F
Site 223
S1667
L
S
E
G
N
G
N
S
F
L
T
S
N
V
A
Site 224
T1670
G
N
G
N
S
F
L
T
S
N
V
A
S
S
K
Site 225
S1671
N
G
N
S
F
L
T
S
N
V
A
S
S
K
S
Site 226
S1675
F
L
T
S
N
V
A
S
S
K
S
E
S
P
V
Site 227
S1676
L
T
S
N
V
A
S
S
K
S
E
S
P
V
P
Site 228
S1678
S
N
V
A
S
S
K
S
E
S
P
V
P
Q
N
Site 229
S1680
V
A
S
S
K
S
E
S
P
V
P
Q
N
E
K
Site 230
S1690
P
Q
N
E
K
A
T
S
A
Q
P
A
A
V
E
Site 231
S1706
A
K
P
V
D
F
P
S
P
K
P
I
P
E
E
Site 232
Y1754
Q
I
Q
K
H
L
D
Y
I
T
Q
A
C
L
K
Site 233
T1756
Q
K
H
L
D
Y
I
T
Q
A
C
L
K
N
K
Site 234
S1787
R
D
I
V
E
N
W
S
V
E
E
Q
A
M
E
Site 235
S1798
Q
A
M
E
M
D
L
S
V
L
Q
Q
V
E
D
Site 236
S1812
D
L
E
R
R
V
A
S
A
S
L
Q
V
K
G
Site 237
S1814
E
R
R
V
A
S
A
S
L
Q
V
K
G
W
M
Site 238
Y1834
S
E
R
E
D
L
V
Y
F
E
H
K
S
F
T
Site 239
S1839
L
V
Y
F
E
H
K
S
F
T
K
L
C
K
E
Site 240
S1857
E
F
T
G
E
D
E
S
S
A
H
A
L
E
R
Site 241
S1858
F
T
G
E
D
E
S
S
A
H
A
L
E
R
K
Site 242
S1866
A
H
A
L
E
R
K
S
D
N
P
L
D
I
A
Site 243
T1875
N
P
L
D
I
A
V
T
R
L
A
D
L
E
R
Site 244
S1904
R
V
W
R
R
A
L
S
E
A
R
S
A
A
Q
Site 245
T1999
L
H
V
K
G
K
K
T
N
E
S
K
K
G
K
Site 246
T2011
K
G
K
K
V
T
L
T
G
D
T
E
D
E
D
Site 247
T2014
K
V
T
L
T
G
D
T
E
D
E
D
S
A
S
Site 248
S2019
G
D
T
E
D
E
D
S
A
S
T
S
S
S
L
Site 249
S2021
T
E
D
E
D
S
A
S
T
S
S
S
L
K
R
Site 250
S2023
D
E
D
S
A
S
T
S
S
S
L
K
R
G
N
Site 251
S2025
D
S
A
S
T
S
S
S
L
K
R
G
N
K
D
Site 252
T2042
K
R
K
M
E
E
N
T
S
I
N
L
S
K
Q
Site 253
S2043
R
K
M
E
E
N
T
S
I
N
L
S
K
Q
E
Site 254
S2047
E
N
T
S
I
N
L
S
K
Q
E
S
F
T
S
Site 255
S2051
I
N
L
S
K
Q
E
S
F
T
S
V
K
K
P
Site 256
S2054
S
K
Q
E
S
F
T
S
V
K
K
P
K
R
D
Site 257
S2063
K
K
P
K
R
D
D
S
K
D
L
A
L
C
S
Site 258
T2074
A
L
C
S
M
I
L
T
E
M
E
T
H
E
D
Site 259
S2108
I
K
K
P
M
D
F
S
T
I
R
E
K
L
S
Site 260
T2109
K
K
P
M
D
F
S
T
I
R
E
K
L
S
S
Site 261
S2116
T
I
R
E
K
L
S
S
G
Q
Y
P
N
L
E
Site 262
Y2119
E
K
L
S
S
G
Q
Y
P
N
L
E
T
F
A
Site 263
T2124
G
Q
Y
P
N
L
E
T
F
A
L
D
V
R
L
Site 264
T2138
L
V
F
D
N
C
E
T
F
N
E
D
D
S
D
Site 265
S2144
E
T
F
N
E
D
D
S
D
I
G
R
A
G
H
Site 266
Y2156
A
G
H
N
M
R
K
Y
F
E
K
K
W
T
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation