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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FFR
Full Name:
Protein fat-free homolog
Alias:
ANG2; ANG3; C11orf2; C11orf3; Chromosome 11 open reading frame 2; CK002; PP5382
Type:
Unknown function
Mass (Da):
86042
Number AA:
782
UniProt ID:
Q9UID3
International Prot ID:
IPI00001710
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006869
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
A
A
A
A
G
P
S
P
G
S
G
P
G
D
Site 2
S13
A
A
G
P
S
P
G
S
G
P
G
D
S
P
E
Site 3
S18
P
G
S
G
P
G
D
S
P
E
G
P
E
G
E
Site 4
Y40
A
H
G
M
L
K
L
Y
Y
G
L
S
E
G
E
Site 5
Y41
H
G
M
L
K
L
Y
Y
G
L
S
E
G
E
A
Site 6
S44
L
K
L
Y
Y
G
L
S
E
G
E
A
A
G
R
Site 7
T61
G
P
D
P
L
D
P
T
D
L
N
G
A
H
F
Site 8
S89
P
L
A
Q
L
M
D
S
E
T
D
M
V
R
Q
Site 9
T91
A
Q
L
M
D
S
E
T
D
M
V
R
Q
I
R
Site 10
S102
R
Q
I
R
A
L
D
S
D
M
Q
T
L
V
Y
Site 11
T106
A
L
D
S
D
M
Q
T
L
V
Y
E
N
Y
N
Site 12
Y109
S
D
M
Q
T
L
V
Y
E
N
Y
N
K
F
I
Site 13
Y112
Q
T
L
V
Y
E
N
Y
N
K
F
I
S
A
T
Site 14
T119
Y
N
K
F
I
S
A
T
D
T
I
R
K
M
K
Site 15
T121
K
F
I
S
A
T
D
T
I
R
K
M
K
N
D
Site 16
T141
D
E
M
D
R
L
A
T
N
M
A
V
I
T
D
Site 17
S154
T
D
F
S
A
R
I
S
A
T
L
Q
D
R
H
Site 18
T165
Q
D
R
H
E
R
I
T
K
L
A
G
V
H
A
Site 19
S185
Q
F
L
F
E
L
P
S
R
L
T
K
C
V
E
Site 20
Y196
K
C
V
E
L
G
A
Y
G
Q
A
V
R
Y
Q
Site 21
Y213
A
Q
A
V
L
Q
Q
Y
Q
H
L
P
S
F
R
Site 22
S218
Q
Q
Y
Q
H
L
P
S
F
R
A
I
Q
D
D
Site 23
S294
L
E
A
E
L
G
P
S
P
P
A
P
D
V
L
Site 24
T304
A
P
D
V
L
E
F
T
D
H
G
G
S
G
F
Site 25
Y348
A
R
Q
L
G
S
R
Y
F
A
L
V
E
R
R
Site 26
S366
E
Q
G
G
G
D
N
S
L
L
V
R
A
L
D
Site 27
S473
L
F
T
A
K
E
V
S
F
S
N
K
P
Y
F
Site 28
S475
T
A
K
E
V
S
F
S
N
K
P
Y
F
R
G
Site 29
Y479
V
S
F
S
N
K
P
Y
F
R
G
E
F
C
S
Site 30
S486
Y
F
R
G
E
F
C
S
Q
G
V
R
E
G
L
Site 31
S507
S
M
C
Q
T
A
Q
S
F
C
D
S
P
G
E
Site 32
S511
T
A
Q
S
F
C
D
S
P
G
E
K
G
G
A
Site 33
T571
L
C
A
E
A
R
E
T
A
R
R
L
L
T
H
Site 34
T577
E
T
A
R
R
L
L
T
H
Y
V
K
V
Q
G
Site 35
Y579
A
R
R
L
L
T
H
Y
V
K
V
Q
G
L
V
Site 36
S594
I
S
Q
M
L
R
K
S
V
E
T
R
D
W
L
Site 37
T597
M
L
R
K
S
V
E
T
R
D
W
L
S
T
L
Site 38
S602
V
E
T
R
D
W
L
S
T
L
E
P
R
N
V
Site 39
T603
E
T
R
D
W
L
S
T
L
E
P
R
N
V
R
Site 40
T620
M
K
R
V
V
E
D
T
T
A
I
D
V
Q
V
Site 41
Y631
D
V
Q
V
G
L
L
Y
E
E
G
V
R
K
A
Site 42
S640
E
G
V
R
K
A
Q
S
S
D
S
S
K
R
T
Site 43
S641
G
V
R
K
A
Q
S
S
D
S
S
K
R
T
F
Site 44
S643
R
K
A
Q
S
S
D
S
S
K
R
T
F
S
V
Site 45
S644
K
A
Q
S
S
D
S
S
K
R
T
F
S
V
Y
Site 46
T647
S
S
D
S
S
K
R
T
F
S
V
Y
S
S
S
Site 47
S649
D
S
S
K
R
T
F
S
V
Y
S
S
S
R
Q
Site 48
Y651
S
K
R
T
F
S
V
Y
S
S
S
R
Q
Q
G
Site 49
S652
K
R
T
F
S
V
Y
S
S
S
R
Q
Q
G
R
Site 50
S653
R
T
F
S
V
Y
S
S
S
R
Q
Q
G
R
Y
Site 51
S654
T
F
S
V
Y
S
S
S
R
Q
Q
G
R
Y
A
Site 52
Y660
S
S
R
Q
Q
G
R
Y
A
P
S
Y
T
P
S
Site 53
S663
Q
Q
G
R
Y
A
P
S
Y
T
P
S
A
P
M
Site 54
Y664
Q
G
R
Y
A
P
S
Y
T
P
S
A
P
M
D
Site 55
T665
G
R
Y
A
P
S
Y
T
P
S
A
P
M
D
T
Site 56
S667
Y
A
P
S
Y
T
P
S
A
P
M
D
T
N
L
Site 57
T672
T
P
S
A
P
M
D
T
N
L
L
S
N
I
Q
Site 58
S676
P
M
D
T
N
L
L
S
N
I
Q
K
L
F
S
Site 59
S683
S
N
I
Q
K
L
F
S
E
R
I
D
V
F
S
Site 60
S690
S
E
R
I
D
V
F
S
P
V
E
F
N
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation