KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FEZ2
Full Name:
Fasciculation and elongation protein zeta-2
Alias:
Fasciculation and elongation protein zeta 2; HUM3CL; Pre-T/NK cell associated protein (3Cl); Zygin II; Zygin-2
Type:
Unknown function
Mass (Da):
39666
Number AA:
353
UniProt ID:
Q9UHY8
International Prot ID:
IPI00006098
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007411
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
D
G
D
W
Q
D
F
Y
E
F
Q
E
P
A
R
Site 2
S19
E
F
Q
E
P
A
R
S
L
L
D
Q
E
N
C
Site 3
S29
D
Q
E
N
C
N
A
S
P
E
P
G
A
E
A
Site 4
S59
C
S
L
E
E
K
L
S
L
C
F
R
P
S
D
Site 5
S65
L
S
L
C
F
R
P
S
D
P
G
A
E
P
P
Site 6
T74
P
G
A
E
P
P
R
T
A
V
R
P
I
T
E
Site 7
T80
R
T
A
V
R
P
I
T
E
R
S
L
L
Q
G
Site 8
S83
V
R
P
I
T
E
R
S
L
L
Q
G
D
E
I
Site 9
Y98
W
N
A
L
T
D
N
Y
G
N
V
M
P
V
D
Site 10
S109
M
P
V
D
W
K
S
S
H
T
R
T
L
H
L
Site 11
T113
W
K
S
S
H
T
R
T
L
H
L
L
T
L
N
Site 12
T118
T
R
T
L
H
L
L
T
L
N
L
S
E
K
G
Site 13
S122
H
L
L
T
L
N
L
S
E
K
G
V
S
D
S
Site 14
S127
N
L
S
E
K
G
V
S
D
S
L
L
F
D
T
Site 15
S129
S
E
K
G
V
S
D
S
L
L
F
D
T
S
D
Site 16
T134
S
D
S
L
L
F
D
T
S
D
D
E
E
L
R
Site 17
S135
D
S
L
L
F
D
T
S
D
D
E
E
L
R
E
Site 18
T161
V
N
D
E
P
L
F
T
A
D
Q
V
I
E
E
Site 19
S176
I
E
E
M
M
Q
E
S
P
D
P
E
D
D
E
Site 20
T184
P
D
P
E
D
D
E
T
P
T
Q
S
D
R
L
Site 21
T186
P
E
D
D
E
T
P
T
Q
S
D
R
L
S
M
Site 22
S188
D
D
E
T
P
T
Q
S
D
R
L
S
M
L
S
Site 23
S192
P
T
Q
S
D
R
L
S
M
L
S
Q
E
I
Q
Site 24
S195
S
D
R
L
S
M
L
S
Q
E
I
Q
T
L
K
Site 25
T200
M
L
S
Q
E
I
Q
T
L
K
R
S
S
T
G
Site 26
S204
E
I
Q
T
L
K
R
S
S
T
G
S
Y
E
E
Site 27
S205
I
Q
T
L
K
R
S
S
T
G
S
Y
E
E
R
Site 28
T206
Q
T
L
K
R
S
S
T
G
S
Y
E
E
R
V
Site 29
S208
L
K
R
S
S
T
G
S
Y
E
E
R
V
K
R
Site 30
Y209
K
R
S
S
T
G
S
Y
E
E
R
V
K
R
L
Site 31
S217
E
E
R
V
K
R
L
S
V
S
E
L
N
E
I
Site 32
S219
R
V
K
R
L
S
V
S
E
L
N
E
I
L
E
Site 33
T230
E
I
L
E
E
I
E
T
A
I
K
E
Y
S
E
Site 34
S236
E
T
A
I
K
E
Y
S
E
E
L
V
Q
Q
L
Site 35
S288
K
K
L
K
N
G
S
S
Q
N
G
K
N
E
R
Site 36
S296
Q
N
G
K
N
E
R
S
H
M
P
G
T
Y
L
Site 37
T301
E
R
S
H
M
P
G
T
Y
L
T
T
V
I
P
Site 38
Y302
R
S
H
M
P
G
T
Y
L
T
T
V
I
P
Y
Site 39
T304
H
M
P
G
T
Y
L
T
T
V
I
P
Y
E
K
Site 40
T305
M
P
G
T
Y
L
T
T
V
I
P
Y
E
K
K
Site 41
Y309
Y
L
T
T
V
I
P
Y
E
K
K
N
G
P
P
Site 42
S317
E
K
K
N
G
P
P
S
V
E
D
L
Q
I
L
Site 43
S335
L
R
A
M
K
E
D
S
E
K
V
P
S
L
L
Site 44
S340
E
D
S
E
K
V
P
S
L
L
T
D
Y
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation