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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EMR2
Full Name:
EGF-like module-containing mucin-like hormone receptor-like 2
Alias:
EGF-like module receptor 2
Type:
Receptor, micellaneous
Mass (Da):
90472
Number AA:
823
UniProt ID:
Q9UHX3
International Prot ID:
IPI00296277
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007218
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
L
T
L
P
G
A
E
T
Q
D
S
R
G
C
A
Site 2
S53
R
C
N
P
G
F
S
S
F
S
E
I
I
T
T
Site 3
S55
N
P
G
F
S
S
F
S
E
I
I
T
T
P
M
Site 4
T59
S
S
F
S
E
I
I
T
T
P
M
E
T
C
D
Site 5
T60
S
F
S
E
I
I
T
T
P
M
E
T
C
D
D
Site 6
T73
D
D
I
N
E
C
A
T
L
S
K
V
S
C
G
Site 7
Y92
C
W
N
T
E
G
S
Y
D
C
V
C
S
P
G
Site 8
S97
G
S
Y
D
C
V
C
S
P
G
Y
E
P
V
S
Site 9
Y100
D
C
V
C
S
P
G
Y
E
P
V
S
G
A
K
Site 10
S104
S
P
G
Y
E
P
V
S
G
A
K
T
F
K
N
Site 11
T108
E
P
V
S
G
A
K
T
F
K
N
E
S
E
N
Site 12
T116
F
K
N
E
S
E
N
T
C
Q
D
V
D
E
C
Site 13
Y133
N
P
R
L
C
K
S
Y
G
T
C
V
N
T
L
Site 14
S201
G
W
Q
P
I
P
G
S
P
N
G
P
N
N
T
Site 15
T232
S
S
T
V
C
F
N
T
V
G
S
Y
S
C
R
Site 16
T266
C
E
D
M
T
F
S
T
W
T
P
P
P
G
V
Site 17
T268
D
M
T
F
S
T
W
T
P
P
P
G
V
H
S
Site 18
S275
T
P
P
P
G
V
H
S
Q
T
L
S
R
F
F
Site 19
T277
P
P
G
V
H
S
Q
T
L
S
R
F
F
D
K
Site 20
S279
G
V
H
S
Q
T
L
S
R
F
F
D
K
V
Q
Site 21
Y292
V
Q
D
L
G
R
D
Y
K
P
G
L
A
N
N
Site 22
T320
E
A
P
G
D
L
E
T
L
P
R
L
Q
Q
H
Site 23
S345
E
D
V
L
R
G
L
S
K
N
L
S
N
G
L
Site 24
S349
R
G
L
S
K
N
L
S
N
G
L
L
N
F
S
Site 25
S356
S
N
G
L
L
N
F
S
Y
P
A
G
T
E
L
Site 26
Y357
N
G
L
L
N
F
S
Y
P
A
G
T
E
L
S
Site 27
S364
Y
P
A
G
T
E
L
S
L
E
V
Q
K
Q
V
Site 28
S374
V
Q
K
Q
V
D
R
S
V
T
L
R
Q
N
Q
Site 29
T376
K
Q
V
D
R
S
V
T
L
R
Q
N
Q
A
V
Site 30
S394
D
W
N
Q
A
Q
K
S
G
D
P
G
P
S
V
Site 31
S454
D
V
I
S
A
F
L
S
N
N
D
T
Q
N
L
Site 32
T458
A
F
L
S
N
N
D
T
Q
N
L
S
S
P
V
Site 33
S462
N
N
D
T
Q
N
L
S
S
P
V
T
F
T
F
Site 34
S463
N
D
T
Q
N
L
S
S
P
V
T
F
T
F
S
Site 35
T466
Q
N
L
S
S
P
V
T
F
T
F
S
H
R
S
Site 36
S470
S
P
V
T
F
T
F
S
H
R
S
V
I
P
R
Site 37
S473
T
F
T
F
S
H
R
S
V
I
P
R
Q
K
V
Site 38
T505
T
G
C
S
T
I
G
T
R
D
T
S
T
I
C
Site 39
T508
S
T
I
G
T
R
D
T
S
T
I
C
R
C
T
Site 40
T510
I
G
T
R
D
T
S
T
I
C
R
C
T
H
L
Site 41
Y636
R
N
L
T
V
V
N
Y
S
S
I
N
R
F
M
Site 42
S638
L
T
V
V
N
Y
S
S
I
N
R
F
M
K
K
Site 43
Y670
A
A
S
R
P
H
L
Y
G
T
P
S
R
C
W
Site 44
T672
S
R
P
H
L
Y
G
T
P
S
R
C
W
L
Q
Site 45
S715
W
I
L
K
N
R
L
S
S
L
N
S
E
V
S
Site 46
S716
I
L
K
N
R
L
S
S
L
N
S
E
V
S
T
Site 47
S719
N
R
L
S
S
L
N
S
E
V
S
T
L
R
N
Site 48
S722
S
S
L
N
S
E
V
S
T
L
R
N
T
R
M
Site 49
T723
S
L
N
S
E
V
S
T
L
R
N
T
R
M
L
Site 50
T727
E
V
S
T
L
R
N
T
R
M
L
A
F
K
A
Site 51
Y789
S
Q
Q
V
R
E
Q
Y
G
K
W
S
K
G
I
Site 52
T801
K
G
I
R
K
L
K
T
E
S
E
M
H
T
L
Site 53
T807
K
T
E
S
E
M
H
T
L
S
S
S
A
K
A
Site 54
S809
E
S
E
M
H
T
L
S
S
S
A
K
A
D
T
Site 55
S811
E
M
H
T
L
S
S
S
A
K
A
D
T
S
K
Site 56
T816
S
S
S
A
K
A
D
T
S
K
P
S
T
V
N
Site 57
S817
S
S
A
K
A
D
T
S
K
P
S
T
V
N
_
Site 58
T821
A
D
T
S
K
P
S
T
V
N
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation