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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Septin-9
Full Name:
ISOFORM 1 OF SEPTIN-9.
Alias:
AF17q25; KIAA0991; MLL septin-like fusion protein MSF-A; MSF; MSF1; Ov/Br septin; Ovarian/breast septin; Ovarian/Breast septin; PNUTL4; SeptD1; Septin 9; Septin D1; Septin-9
Type:
Cell cycle regulation
Mass (Da):
65401
Number AA:
586
UniProt ID:
Q9UHD8
International Prot ID:
IPI00455033
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0048471
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0051301
GO:0051291
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
K
K
S
Y
S
G
G
T
R
T
S
S
Site 2
T11
S
Y
S
G
G
T
R
T
S
S
G
R
L
R
R
Site 3
S12
Y
S
G
G
T
R
T
S
S
G
R
L
R
R
L
Site 4
S13
S
G
G
T
R
T
S
S
G
R
L
R
R
L
G
Site 5
S22
R
L
R
R
L
G
D
S
S
G
P
A
L
K
R
Site 6
S23
L
R
R
L
G
D
S
S
G
P
A
L
K
R
S
Site 7
S30
S
G
P
A
L
K
R
S
F
E
V
E
E
V
E
Site 8
T38
F
E
V
E
E
V
E
T
P
N
S
T
P
P
R
Site 9
S41
E
E
V
E
T
P
N
S
T
P
P
R
R
V
Q
Site 10
T42
E
V
E
T
P
N
S
T
P
P
R
R
V
Q
T
Site 11
T49
T
P
P
R
R
V
Q
T
P
L
L
R
A
T
V
Site 12
T55
Q
T
P
L
L
R
A
T
V
A
S
S
T
Q
K
Site 13
S58
L
L
R
A
T
V
A
S
S
T
Q
K
F
Q
D
Site 14
T60
R
A
T
V
A
S
S
T
Q
K
F
Q
D
L
G
Site 15
S71
Q
D
L
G
V
K
N
S
E
P
S
A
R
H
V
Site 16
S74
G
V
K
N
S
E
P
S
A
R
H
V
D
S
L
Site 17
S80
P
S
A
R
H
V
D
S
L
S
Q
R
S
P
K
Site 18
S82
A
R
H
V
D
S
L
S
Q
R
S
P
K
A
S
Site 19
S85
V
D
S
L
S
Q
R
S
P
K
A
S
L
R
R
Site 20
S89
S
Q
R
S
P
K
A
S
L
R
R
V
E
L
S
Site 21
S96
S
L
R
R
V
E
L
S
G
P
K
A
A
E
P
Site 22
S105
P
K
A
A
E
P
V
S
R
R
T
E
L
S
I
Site 23
T108
A
E
P
V
S
R
R
T
E
L
S
I
D
I
S
Site 24
S111
V
S
R
R
T
E
L
S
I
D
I
S
S
K
Q
Site 25
S115
T
E
L
S
I
D
I
S
S
K
Q
V
E
N
A
Site 26
T142
A
E
V
L
G
H
K
T
P
E
P
A
P
R
R
Site 27
T150
P
E
P
A
P
R
R
T
E
I
T
I
V
K
P
Site 28
T153
A
P
R
R
T
E
I
T
I
V
K
P
Q
E
S
Site 29
S160
T
I
V
K
P
Q
E
S
A
H
R
R
M
E
P
Site 30
S170
R
R
M
E
P
P
A
S
K
V
P
E
V
P
T
Site 31
S203
A
E
A
P
T
A
P
S
P
A
Q
T
L
E
N
Site 32
T207
T
A
P
S
P
A
Q
T
L
E
N
S
E
P
A
Site 33
S211
P
A
Q
T
L
E
N
S
E
P
A
P
V
S
Q
Site 34
S217
N
S
E
P
A
P
V
S
Q
L
Q
S
R
L
E
Site 35
S221
A
P
V
S
Q
L
Q
S
R
L
E
P
K
P
Q
Site 36
T235
Q
P
P
V
A
E
A
T
P
R
S
Q
E
A
T
Site 37
S238
V
A
E
A
T
P
R
S
Q
E
A
T
E
A
A
Site 38
T242
T
P
R
S
Q
E
A
T
E
A
A
P
S
C
V
Site 39
S247
E
A
T
E
A
A
P
S
C
V
G
D
M
A
D
Site 40
T255
C
V
G
D
M
A
D
T
P
R
D
A
G
L
K
Site 41
S267
G
L
K
Q
A
P
A
S
R
N
E
K
A
P
V
Site 42
Y278
K
A
P
V
D
F
G
Y
V
G
I
D
S
I
L
Site 43
S283
F
G
Y
V
G
I
D
S
I
L
E
Q
M
R
R
Site 44
T313
Q
S
G
L
G
K
S
T
L
I
N
T
L
F
K
Site 45
T317
G
K
S
T
L
I
N
T
L
F
K
S
K
I
S
Site 46
S321
L
I
N
T
L
F
K
S
K
I
S
R
K
S
V
Site 47
S327
K
S
K
I
S
R
K
S
V
Q
P
T
S
E
E
Site 48
T331
S
R
K
S
V
Q
P
T
S
E
E
R
I
P
K
Site 49
S332
R
K
S
V
Q
P
T
S
E
E
R
I
P
K
T
Site 50
T339
S
E
E
R
I
P
K
T
I
E
I
K
S
I
T
Site 51
S344
P
K
T
I
E
I
K
S
I
T
H
D
I
E
E
Site 52
Y387
M
K
F
I
N
D
Q
Y
E
K
Y
L
Q
E
E
Site 53
Y390
I
N
D
Q
Y
E
K
Y
L
Q
E
E
V
N
I
Site 54
T450
I
A
K
A
D
T
L
T
L
E
E
R
V
H
F
Site 55
T462
V
H
F
K
Q
R
I
T
A
D
L
L
S
N
G
Site 56
Y473
L
S
N
G
I
D
V
Y
P
Q
K
E
F
D
E
Site 57
S482
Q
K
E
F
D
E
D
S
E
D
R
L
V
N
E
Site 58
S502
I
P
F
A
V
V
G
S
D
H
E
Y
Q
V
N
Site 59
Y506
V
V
G
S
D
H
E
Y
Q
V
N
G
K
R
I
Site 60
T518
K
R
I
L
G
R
K
T
K
W
G
T
I
E
V
Site 61
T543
L
R
D
L
L
I
R
T
H
M
Q
N
I
K
D
Site 62
Y560
S
S
I
H
F
E
A
Y
R
V
K
R
L
N
E
Site 63
S569
V
K
R
L
N
E
G
S
S
A
M
A
N
G
M
Site 64
S570
K
R
L
N
E
G
S
S
A
M
A
N
G
M
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation