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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SRP68
Full Name:
Signal recognition particle 68 kDa protein
Alias:
signal recognition particle 68 kDa; signal recognition particle 68kDa
Type:
Endoplasmic reticulum
Mass (Da):
70730
Number AA:
627
UniProt ID:
Q9UHB9
International Prot ID:
IPI00168388
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005730
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
G
G
G
G
G
G
G
S
G
G
G
G
G
S
G
Site 2
S22
G
S
G
G
G
G
G
S
G
G
G
G
S
G
G
Site 3
S27
G
G
S
G
G
G
G
S
G
G
G
R
G
A
G
Site 4
S45
N
K
E
N
E
R
P
S
A
G
S
K
A
N
K
Site 5
S48
N
E
R
P
S
A
G
S
K
A
N
K
E
F
G
Site 6
S57
A
N
K
E
F
G
D
S
L
S
L
E
I
L
Q
Site 7
Y83
R
H
G
D
F
Q
R
Y
R
G
Y
C
S
R
R
Site 8
Y86
D
F
Q
R
Y
R
G
Y
C
S
R
R
Q
R
R
Site 9
S88
Q
R
Y
R
G
Y
C
S
R
R
Q
R
R
L
R
Site 10
T97
R
Q
R
R
L
R
K
T
L
N
F
K
M
G
N
Site 11
T119
K
V
T
E
E
L
L
T
D
N
R
Y
L
L
L
Site 12
S157
R
K
R
F
H
L
L
S
R
L
R
K
A
V
K
Site 13
S175
E
L
E
R
L
C
E
S
N
R
V
D
A
K
T
Site 14
T182
S
N
R
V
D
A
K
T
K
L
E
A
Q
A
Y
Site 15
Y189
T
K
L
E
A
Q
A
Y
T
A
Y
L
S
G
M
Site 16
T216
E
A
F
N
K
C
K
T
I
Y
E
K
L
A
S
Site 17
Y218
F
N
K
C
K
T
I
Y
E
K
L
A
S
A
F
Site 18
S223
T
I
Y
E
K
L
A
S
A
F
T
E
E
Q
A
Site 19
Y233
T
E
E
Q
A
V
L
Y
N
Q
R
V
E
E
I
Site 20
S241
N
Q
R
V
E
E
I
S
P
N
I
R
Y
C
A
Site 21
Y246
E
I
S
P
N
I
R
Y
C
A
Y
N
I
G
D
Site 22
S267
L
M
Q
M
R
L
R
S
G
G
T
E
G
L
L
Site 23
T270
M
R
L
R
S
G
G
T
E
G
L
L
A
E
K
Site 24
T283
E
K
L
E
A
L
I
T
Q
T
R
A
K
Q
A
Site 25
T302
E
V
E
W
R
G
R
T
V
P
V
K
I
D
K
Site 26
S339
T
K
E
R
L
F
E
S
M
L
S
E
C
R
D
Site 27
S342
R
L
F
E
S
M
L
S
E
C
R
D
A
I
Q
Site 28
Y364
P
D
Q
K
Q
R
D
Y
I
L
E
G
E
P
G
Site 29
S374
E
G
E
P
G
K
V
S
N
L
Q
Y
L
H
S
Site 30
Y378
G
K
V
S
N
L
Q
Y
L
H
S
Y
L
T
Y
Site 31
S381
S
N
L
Q
Y
L
H
S
Y
L
T
Y
I
K
L
Site 32
T384
Q
Y
L
H
S
Y
L
T
Y
I
K
L
S
T
A
Site 33
Y385
Y
L
H
S
Y
L
T
Y
I
K
L
S
T
A
I
Site 34
S415
Q
Q
Q
P
E
D
D
S
K
R
S
P
R
P
Q
Site 35
S418
P
E
D
D
S
K
R
S
P
R
P
Q
D
L
I
Site 36
T458
Q
K
E
I
G
L
K
T
L
V
F
K
A
Y
R
Site 37
Y473
C
F
F
I
A
Q
S
Y
V
L
V
K
K
W
S
Site 38
Y492
L
Y
D
R
V
L
K
Y
A
N
E
V
N
S
D
Site 39
S506
D
A
G
A
F
K
N
S
L
K
D
L
P
D
V
Site 40
T518
P
D
V
Q
E
L
I
T
Q
V
R
S
E
K
C
Site 41
S522
E
L
I
T
Q
V
R
S
E
K
C
S
L
Q
A
Site 42
T541
D
A
N
D
A
H
Q
T
E
T
S
S
S
Q
V
Site 43
S546
H
Q
T
E
T
S
S
S
Q
V
K
D
N
K
P
Site 44
T560
P
L
V
E
R
F
E
T
F
C
L
D
P
S
L
Site 45
S566
E
T
F
C
L
D
P
S
L
V
T
K
Q
A
N
Site 46
T611
E
D
K
L
E
Q
K
T
K
S
G
L
T
G
Y
Site 47
S613
K
L
E
Q
K
T
K
S
G
L
T
G
Y
I
K
Site 48
Y618
T
K
S
G
L
T
G
Y
I
K
G
I
F
G
F
Site 49
S627
K
G
I
F
G
F
R
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation