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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEC63
Full Name:
Translocation protein SEC63 homolog
Alias:
ERdj2; PRO2507; SEC63L
Type:
Endoplasmic reticulum
Mass (Da):
87997
Number AA:
760
UniProt ID:
Q9UGP8
International Prot ID:
IPI00218922
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005789
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0004872
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0006605
GO:0006612
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
G
Q
Q
F
Q
Y
D
D
S
G
N
T
F
Site 2
Y33
I
V
I
P
A
T
Y
Y
L
W
P
R
D
Q
N
Site 3
Y53
L
K
N
I
R
K
V
Y
G
R
C
M
W
Y
R
Site 4
Y59
V
Y
G
R
C
M
W
Y
R
L
R
L
L
K
P
Site 5
S94
L
F
L
A
Y
K
V
S
K
T
D
R
E
Y
Q
Site 6
T96
L
A
Y
K
V
S
K
T
D
R
E
Y
Q
E
Y
Site 7
Y100
V
S
K
T
D
R
E
Y
Q
E
Y
N
P
Y
E
Site 8
Y103
T
D
R
E
Y
Q
E
Y
N
P
Y
E
V
L
N
Site 9
Y106
E
Y
Q
E
Y
N
P
Y
E
V
L
N
L
D
P
Site 10
S128
K
K
Q
Y
R
L
L
S
L
K
Y
H
P
D
K
Site 11
Y131
Y
R
L
L
S
L
K
Y
H
P
D
K
G
G
D
Site 12
Y149
F
M
R
I
A
K
A
Y
A
A
L
T
D
E
E
Site 13
T153
A
K
A
Y
A
A
L
T
D
E
E
S
R
K
N
Site 14
S157
A
A
L
T
D
E
E
S
R
K
N
W
E
E
F
Site 15
S219
W
Y
R
S
I
R
Y
S
G
D
Q
I
L
I
R
Site 16
Y233
R
T
T
Q
I
Y
T
Y
F
V
Y
K
T
R
N
Site 17
Y260
A
S
E
F
D
P
Q
Y
N
K
D
A
T
S
R
Site 18
T265
P
Q
Y
N
K
D
A
T
S
R
P
T
D
N
I
Site 19
T269
K
D
A
T
S
R
P
T
D
N
I
L
I
P
Q
Site 20
S283
Q
L
I
R
E
I
G
S
I
N
L
K
K
N
E
Site 21
T294
K
K
N
E
P
P
L
T
C
P
Y
S
L
K
A
Site 22
S307
K
A
R
V
L
L
L
S
H
L
A
R
M
K
I
Site 23
T317
A
R
M
K
I
P
E
T
L
E
E
D
Q
Q
F
Site 24
T359
E
R
E
F
R
A
P
T
L
A
S
L
E
N
C
Site 25
S382
Q
G
L
Q
Q
F
K
S
P
L
L
Q
L
P
H
Site 26
S399
E
D
N
L
R
R
V
S
N
H
K
K
Y
K
I
Site 27
Y404
R
V
S
N
H
K
K
Y
K
I
K
T
I
Q
D
Site 28
T408
H
K
K
Y
K
I
K
T
I
Q
D
L
V
S
L
Site 29
S414
K
T
I
Q
D
L
V
S
L
K
E
S
D
R
H
Site 30
S418
D
L
V
S
L
K
E
S
D
R
H
T
L
L
H
Site 31
T422
L
K
E
S
D
R
H
T
L
L
H
F
L
E
D
Site 32
Y432
H
F
L
E
D
E
K
Y
E
E
V
M
A
V
L
Site 33
S451
Y
V
T
M
D
I
K
S
Q
V
L
D
D
E
D
Site 34
S459
Q
V
L
D
D
E
D
S
N
N
I
T
V
G
S
Site 35
T463
D
E
D
S
N
N
I
T
V
G
S
L
V
T
V
Site 36
T475
V
T
V
L
V
K
L
T
R
Q
T
M
A
E
V
Site 37
T478
L
V
K
L
T
R
Q
T
M
A
E
V
F
E
K
Site 38
S488
E
V
F
E
K
E
Q
S
I
C
A
A
E
E
Q
Site 39
S517
K
G
G
W
Q
Q
K
S
K
G
P
K
K
T
A
Site 40
S526
G
P
K
K
T
A
K
S
K
K
K
K
P
L
K
Site 41
T537
K
P
L
K
K
K
P
T
P
V
L
L
P
Q
S
Site 42
S544
T
P
V
L
L
P
Q
S
K
Q
Q
K
Q
K
Q
Site 43
S570
K
E
D
E
E
E
V
S
D
K
G
S
D
S
E
Site 44
S574
E
E
V
S
D
K
G
S
D
S
E
E
E
E
T
Site 45
S576
V
S
D
K
G
S
D
S
E
E
E
E
T
N
R
Site 46
T581
S
D
S
E
E
E
E
T
N
R
D
S
Q
S
E
Site 47
S585
E
E
E
T
N
R
D
S
Q
S
E
K
D
D
G
Site 48
S587
E
T
N
R
D
S
Q
S
E
K
D
D
G
S
D
Site 49
S593
Q
S
E
K
D
D
G
S
D
R
D
S
D
R
E
Site 50
S597
D
D
G
S
D
R
D
S
D
R
E
Q
D
E
K
Site 51
S619
E
W
Q
E
L
Q
Q
S
I
Q
R
K
E
R
A
Site 52
T630
K
E
R
A
L
L
E
T
K
S
K
I
T
H
P
Site 53
S632
R
A
L
L
E
T
K
S
K
I
T
H
P
V
Y
Site 54
Y639
S
K
I
T
H
P
V
Y
S
L
Y
F
P
E
E
Site 55
Y642
T
H
P
V
Y
S
L
Y
F
P
E
E
K
Q
E
Site 56
T662
I
A
D
R
K
E
Q
T
L
I
S
M
P
Y
H
Site 57
T672
S
M
P
Y
H
V
C
T
L
K
D
T
E
E
V
Site 58
T676
H
V
C
T
L
K
D
T
E
E
V
E
L
K
F
Site 59
Y692
A
P
G
K
P
G
N
Y
Q
Y
T
V
F
L
R
Site 60
Y694
G
K
P
G
N
Y
Q
Y
T
V
F
L
R
S
D
Site 61
T695
K
P
G
N
Y
Q
Y
T
V
F
L
R
S
D
S
Site 62
S702
T
V
F
L
R
S
D
S
Y
M
G
L
D
Q
I
Site 63
Y703
V
F
L
R
S
D
S
Y
M
G
L
D
Q
I
K
Site 64
S742
G
D
E
D
Q
E
D
S
E
G
F
E
D
S
F
Site 65
S748
D
S
E
G
F
E
D
S
F
E
E
E
E
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation