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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRKAG3
Full Name:
5'-AMP-activated protein kinase subunit gamma-3
Alias:
5'-AMP-activated protein kinase, gamma-3 subunit; AAKG3; AMP-activated protein kinase, non-catalytic gamma-3 subunit; AMPK gamma3; AMPK gamma-3 chain; AMPKG3; Protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Type:
Uncharacterized protein
Mass (Da):
54258
Number AA:
489
UniProt ID:
Q9UGI9
International Prot ID:
IPI00220340
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004679
GO:0019901
PhosphoSite+
KinaseNET
Biological Process:
GO:0006633
GO:0007243
GO:0046320
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
L
E
H
A
L
R
R
T
P
S
W
S
S
L
G
Site 2
S14
H
A
L
R
R
T
P
S
W
S
S
L
G
G
S
Site 3
S16
L
R
R
T
P
S
W
S
S
L
G
G
S
E
H
Site 4
S17
R
R
T
P
S
W
S
S
L
G
G
S
E
H
Q
Site 5
S21
S
W
S
S
L
G
G
S
E
H
Q
E
M
S
F
Site 6
S27
G
S
E
H
Q
E
M
S
F
L
E
Q
E
N
S
Site 7
S34
S
F
L
E
Q
E
N
S
S
S
W
P
S
P
A
Site 8
S35
F
L
E
Q
E
N
S
S
S
W
P
S
P
A
V
Site 9
S36
L
E
Q
E
N
S
S
S
W
P
S
P
A
V
T
Site 10
S39
E
N
S
S
S
W
P
S
P
A
V
T
S
S
S
Site 11
T43
S
W
P
S
P
A
V
T
S
S
S
E
R
I
R
Site 12
S45
P
S
P
A
V
T
S
S
S
E
R
I
R
G
K
Site 13
S46
S
P
A
V
T
S
S
S
E
R
I
R
G
K
R
Site 14
T61
R
A
K
A
L
R
W
T
R
Q
K
S
V
E
E
Site 15
S65
L
R
W
T
R
Q
K
S
V
E
E
G
E
P
P
Site 16
S80
G
Q
G
E
G
P
R
S
R
P
A
A
E
S
T
Site 17
S86
R
S
R
P
A
A
E
S
T
G
L
E
A
T
F
Site 18
T92
E
S
T
G
L
E
A
T
F
P
K
T
T
P
L
Site 19
T96
L
E
A
T
F
P
K
T
T
P
L
A
Q
A
D
Site 20
T97
E
A
T
F
P
K
T
T
P
L
A
Q
A
D
P
Site 21
T109
A
D
P
A
G
V
G
T
P
P
T
G
W
D
C
Site 22
T112
A
G
V
G
T
P
P
T
G
W
D
C
L
P
S
Site 23
S119
T
G
W
D
C
L
P
S
D
C
T
A
S
A
A
Site 24
T122
D
C
L
P
S
D
C
T
A
S
A
A
G
S
S
Site 25
S124
L
P
S
D
C
T
A
S
A
A
G
S
S
T
D
Site 26
S128
C
T
A
S
A
A
G
S
S
T
D
D
V
E
L
Site 27
T142
L
A
T
E
F
P
A
T
E
A
W
E
C
E
L
Site 28
S162
E
R
P
A
L
C
L
S
P
Q
A
P
F
P
K
Site 29
Y184
R
K
P
G
A
Q
I
Y
M
R
F
M
Q
E
H
Site 30
Y194
F
M
Q
E
H
T
C
Y
D
A
M
A
T
S
S
Site 31
S232
R
A
A
P
L
W
D
S
K
K
Q
S
F
V
G
Site 32
S256
V
L
H
R
Y
Y
R
S
P
L
V
Q
I
Y
E
Site 33
Y276
I
E
T
W
R
E
I
Y
L
Q
G
C
F
K
P
Site 34
S288
F
K
P
L
V
S
I
S
P
N
D
S
L
F
E
Site 35
T323
G
N
V
L
H
I
L
T
H
K
R
L
L
K
F
Site 36
S336
K
F
L
H
I
F
G
S
L
L
P
R
P
S
F
Site 37
S342
G
S
L
L
P
R
P
S
F
L
Y
R
T
I
Q
Site 38
Y345
L
P
R
P
S
F
L
Y
R
T
I
Q
D
L
G
Site 39
T347
R
P
S
F
L
Y
R
T
I
Q
D
L
G
I
G
Site 40
S416
T
Y
N
H
L
D
M
S
V
G
E
A
L
R
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation