KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
IFT172
Full Name:
Intraflagellar transport protein 172 homolog
Alias:
Intraflagellar transport 172; Intraflagellar transport protein 172; Osm-1; Selective LIM binding factor homolog; SLB; Wim
Type:
Unknown function
Mass (Da):
197576
Number AA:
1749
UniProt ID:
Q9UG01
International Prot ID:
IPI00410096
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005929
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0042384
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
H
L
K
H
L
R
T
L
L
S
P
Q
D
G
Site 2
S11
K
H
L
R
T
L
L
S
P
Q
D
G
A
A
K
Site 3
Y43
V
D
R
V
V
L
L
Y
D
E
H
G
E
R
R
Site 4
S54
G
E
R
R
D
K
F
S
T
K
P
A
D
M
K
Site 5
T55
E
R
R
D
K
F
S
T
K
P
A
D
M
K
Y
Site 6
Y62
T
K
P
A
D
M
K
Y
G
R
K
S
Y
M
V
Site 7
Y67
M
K
Y
G
R
K
S
Y
M
V
K
G
M
A
F
Site 8
S78
G
M
A
F
S
P
D
S
T
K
I
A
I
G
Q
Site 9
T79
M
A
F
S
P
D
S
T
K
I
A
I
G
Q
T
Site 10
Y91
G
Q
T
D
N
I
I
Y
V
Y
K
I
G
E
D
Site 11
Y93
T
D
N
I
I
Y
V
Y
K
I
G
E
D
W
G
Site 12
T142
V
R
L
A
N
T
K
T
N
K
S
S
T
I
Y
Site 13
S145
A
N
T
K
T
N
K
S
S
T
I
Y
G
T
E
Site 14
S146
N
T
K
T
N
K
S
S
T
I
Y
G
T
E
S
Site 15
T147
T
K
T
N
K
S
S
T
I
Y
G
T
E
S
Y
Site 16
Y149
T
N
K
S
S
T
I
Y
G
T
E
S
Y
V
V
Site 17
T151
K
S
S
T
I
Y
G
T
E
S
Y
V
V
S
L
Site 18
S157
G
T
E
S
Y
V
V
S
L
T
T
N
C
S
G
Site 19
T159
E
S
Y
V
V
S
L
T
T
N
C
S
G
K
G
Site 20
Y179
A
D
G
T
I
V
R
Y
F
F
D
D
E
G
S
Site 21
S186
Y
F
F
D
D
E
G
S
G
E
S
Q
G
K
L
Site 22
Y222
C
D
R
K
I
V
A
Y
G
K
E
G
H
M
L
Site 23
T231
K
E
G
H
M
L
Q
T
F
D
Y
S
R
D
P
Site 24
Y234
H
M
L
Q
T
F
D
Y
S
R
D
P
Q
E
R
Site 25
S235
M
L
Q
T
F
D
Y
S
R
D
P
Q
E
R
E
Site 26
T244
D
P
Q
E
R
E
F
T
T
A
V
S
S
P
G
Site 27
T245
P
Q
E
R
E
F
T
T
A
V
S
S
P
G
G
Site 28
S254
V
S
S
P
G
G
Q
S
V
V
L
G
S
Y
D
Site 29
S259
G
Q
S
V
V
L
G
S
Y
D
R
L
R
V
F
Site 30
Y260
Q
S
V
V
L
G
S
Y
D
R
L
R
V
F
N
Site 31
S273
F
N
W
I
P
R
R
S
I
W
E
E
A
K
P
Site 32
S299
L
A
W
K
R
D
G
S
R
L
C
V
G
T
L
Site 33
Y322
C
C
L
R
R
S
I
Y
K
N
K
F
E
L
T
Site 34
T329
Y
K
N
K
F
E
L
T
Y
V
G
P
S
Q
V
Site 35
Y330
K
N
K
F
E
L
T
Y
V
G
P
S
Q
V
I
Site 36
S351
G
T
R
V
V
L
K
S
H
Y
G
Y
E
V
E
Site 37
Y355
V
L
K
S
H
Y
G
Y
E
V
E
E
V
K
I
Site 38
Y368
K
I
L
G
K
E
R
Y
L
V
A
H
T
S
E
Site 39
S388
D
L
N
T
N
R
L
S
E
I
A
W
Q
G
S
Site 40
Y401
G
S
G
G
N
E
K
Y
F
F
E
N
E
N
V
Site 41
Y422
G
E
L
T
L
V
E
Y
G
N
N
D
T
L
G
Site 42
S430
G
N
N
D
T
L
G
S
V
R
T
E
F
M
N
Site 43
T433
D
T
L
G
S
V
R
T
E
F
M
N
P
H
L
Site 44
T453
N
E
R
C
Q
R
G
T
E
D
N
K
K
L
A
Site 45
Y461
E
D
N
K
K
L
A
Y
L
I
D
I
K
T
I
Site 46
T467
A
Y
L
I
D
I
K
T
I
A
I
V
D
L
I
Site 47
T481
I
G
G
Y
N
I
G
T
V
S
H
E
S
R
V
Site 48
T496
D
W
L
E
L
N
E
T
G
H
K
L
L
F
R
Site 49
Y512
R
K
L
R
L
H
L
Y
D
I
E
S
C
S
K
Site 50
T559
I
E
A
P
E
R
V
T
M
F
T
I
R
G
D
Site 51
T577
L
E
R
G
G
G
K
T
E
V
M
V
M
E
G
Site 52
T601
E
G
L
I
E
F
G
T
A
I
D
D
G
N
Y
Site 53
T612
D
G
N
Y
I
R
A
T
A
F
L
E
T
L
E
Site 54
T621
F
L
E
T
L
E
M
T
P
E
T
E
A
M
W
Site 55
T630
E
T
E
A
M
W
K
T
L
S
K
L
A
L
E
Site 56
S632
E
A
M
W
K
T
L
S
K
L
A
L
E
A
R
Site 57
T663
K
A
R
F
L
H
E
T
N
E
I
A
D
Q
V
Site 58
S671
N
E
I
A
D
Q
V
S
R
E
Y
G
G
E
G
Site 59
Y674
A
D
Q
V
S
R
E
Y
G
G
E
G
T
D
F
Site 60
Y682
G
G
E
G
T
D
F
Y
Q
V
R
A
R
L
A
Site 61
Y743
L
E
K
L
R
R
S
Y
Y
Q
W
L
M
D
T
Site 62
Y744
E
K
L
R
R
S
Y
Y
Q
W
L
M
D
T
Q
Site 63
S762
R
A
G
E
L
Q
E
S
Q
G
D
G
L
A
A
Site 64
T910
L
D
L
Q
D
R
N
T
A
S
K
Y
Y
P
L
Site 65
S912
L
Q
D
R
N
T
A
S
K
Y
Y
P
L
V
A
Site 66
Y914
D
R
N
T
A
S
K
Y
Y
P
L
V
A
Q
H
Site 67
Y915
R
N
T
A
S
K
Y
Y
P
L
V
A
Q
H
Y
Site 68
S924
L
V
A
Q
H
Y
A
S
L
Q
E
Y
E
I
A
Site 69
Y928
H
Y
A
S
L
Q
E
Y
E
I
A
E
E
L
Y
Site 70
T936
E
I
A
E
E
L
Y
T
K
G
D
R
T
K
D
Site 71
T941
L
Y
T
K
G
D
R
T
K
D
A
I
D
M
Y
Site 72
Y948
T
K
D
A
I
D
M
Y
T
Q
A
G
R
W
E
Site 73
Y974
P
E
D
V
S
V
L
Y
I
T
Q
A
Q
E
M
Site 74
Y987
E
M
E
K
Q
G
K
Y
R
E
A
E
R
L
Y
Site 75
Y994
Y
R
E
A
E
R
L
Y
V
T
V
Q
E
P
D
Site 76
Y1007
P
D
L
A
I
T
M
Y
K
K
H
K
L
Y
D
Site 77
Y1013
M
Y
K
K
H
K
L
Y
D
D
M
I
R
L
V
Site 78
S1029
K
H
H
P
D
L
L
S
D
T
H
L
H
L
G
Site 79
T1031
H
P
D
L
L
S
D
T
H
L
H
L
G
K
E
Site 80
Y1052
L
Q
E
A
E
Y
H
Y
L
E
A
Q
E
W
K
Site 81
T1061
E
A
Q
E
W
K
A
T
V
N
M
Y
R
A
S
Site 82
Y1075
S
G
L
W
E
E
A
Y
R
V
A
R
T
Q
G
Site 83
Y1092
N
A
H
K
H
V
A
Y
L
W
A
K
S
L
G
Site 84
T1141
R
L
A
L
K
H
K
T
P
E
V
H
L
K
Y
Site 85
Y1235
R
P
G
L
A
L
N
Y
Y
K
E
A
G
L
W
Site 86
Y1236
P
G
L
A
L
N
Y
Y
K
E
A
G
L
W
S
Site 87
Y1252
A
L
R
I
C
K
D
Y
V
P
S
Q
L
E
A
Site 88
Y1264
L
E
A
L
Q
E
E
Y
E
R
E
A
T
K
K
Site 89
T1269
E
E
Y
E
R
E
A
T
K
K
G
A
R
G
V
Site 90
Y1292
H
W
E
Q
A
G
E
Y
S
R
A
V
D
C
Y
Site 91
Y1299
Y
S
R
A
V
D
C
Y
L
K
V
R
D
S
G
Site 92
S1305
C
Y
L
K
V
R
D
S
G
N
S
G
L
A
E
Site 93
S1308
K
V
R
D
S
G
N
S
G
L
A
E
K
C
W
Site 94
Y1388
A
K
E
L
D
P
R
Y
E
D
Y
V
D
Q
H
Site 95
Y1391
L
D
P
R
Y
E
D
Y
V
D
Q
H
Y
K
E
Site 96
Y1396
E
D
Y
V
D
Q
H
Y
K
E
F
L
K
N
Q
Site 97
Y1445
N
Y
K
I
L
H
K
Y
V
A
L
Y
A
T
H
Site 98
Y1481
N
P
Q
N
F
N
I
Y
K
R
I
F
T
D
M
Site 99
T1486
N
I
Y
K
R
I
F
T
D
M
V
S
S
P
G
Site 100
S1490
R
I
F
T
D
M
V
S
S
P
G
T
N
C
A
Site 101
T1494
D
M
V
S
S
P
G
T
N
C
A
E
A
Y
H
Site 102
S1520
L
C
E
N
L
V
K
S
S
E
A
N
S
P
A
Site 103
S1521
C
E
N
L
V
K
S
S
E
A
N
S
P
A
H
Site 104
S1525
V
K
S
S
E
A
N
S
P
A
H
E
E
F
K
Site 105
T1533
P
A
H
E
E
F
K
T
M
L
L
I
A
H
Y
Site 106
S1545
A
H
Y
Y
A
T
R
S
A
A
Q
S
V
K
Q
Site 107
S1549
A
T
R
S
A
A
Q
S
V
K
Q
L
E
T
V
Site 108
T1568
S
V
S
L
L
R
H
T
Q
L
L
P
V
D
K
Site 109
T1604
L
N
R
F
L
D
L
T
D
A
I
E
E
G
T
Site 110
S1618
T
L
D
G
L
D
H
S
D
F
Q
D
T
D
I
Site 111
T1623
D
H
S
D
F
Q
D
T
D
I
P
F
E
V
P
Site 112
T1651
E
V
R
D
W
V
L
T
V
S
M
D
Q
R
L
Site 113
S1653
R
D
W
V
L
T
V
S
M
D
Q
R
L
E
Q
Site 114
Y1670
P
R
D
E
R
G
A
Y
E
A
S
L
V
A
A
Site 115
S1673
E
R
G
A
Y
E
A
S
L
V
A
A
S
T
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation