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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXL17
Full Name:
F-box/LRR-repeat protein 17
Alias:
DKFZP434C1715; Fbl17; F-box and leucine-rich repeat protein 17; F-box only protein 13; Fbx13; FBXO13; FXL17
Type:
Mass (Da):
75676
Number AA:
701
UniProt ID:
Q9UF56
International Prot ID:
IPI00004341
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
H
L
L
S
K
E
P
R
N
R
P
Site 2
S14
K
E
P
R
N
R
P
S
Q
K
R
P
R
C
C
Site 3
T37
L
L
R
L
P
R
R
T
P
A
K
V
P
P
Q
Site 4
S50
P
Q
P
A
A
P
R
S
R
D
C
F
F
R
G
Site 5
S83
P
E
E
E
P
P
L
S
P
P
P
R
D
G
A
Site 6
Y91
P
P
P
R
D
G
A
Y
A
A
A
S
S
S
Q
Site 7
S95
D
G
A
Y
A
A
A
S
S
S
Q
H
L
A
R
Site 8
S97
A
Y
A
A
A
S
S
S
Q
H
L
A
R
R
Y
Site 9
Y104
S
Q
H
L
A
R
R
Y
A
A
L
A
A
E
D
Site 10
S136
A
A
A
A
S
A
S
S
P
A
S
C
C
K
E
Site 11
S158
A
W
E
Q
Q
G
R
S
L
F
L
A
S
L
G
Site 12
T183
V
Q
L
F
R
G
P
T
P
S
P
A
E
L
P
Site 13
S185
L
F
R
G
P
T
P
S
P
A
E
L
P
T
P
Site 14
T191
P
S
P
A
E
L
P
T
P
P
E
M
V
C
K
Site 15
T208
G
A
G
V
P
A
C
T
P
C
K
Q
P
R
C
Site 16
S238
G
P
A
G
G
G
A
S
P
P
R
P
P
D
A
Site 17
S263
Q
P
L
C
P
P
P
S
S
P
T
S
E
G
A
Site 18
S264
P
L
C
P
P
P
S
S
P
T
S
E
G
A
P
Site 19
S267
P
P
P
S
S
P
T
S
E
G
A
P
T
E
A
Site 20
T272
P
T
S
E
G
A
P
T
E
A
G
G
D
A
V
Site 21
S288
A
G
G
T
A
P
L
S
A
Q
Q
Q
H
E
C
Site 22
S303
G
D
A
D
C
R
E
S
P
E
N
P
C
D
C
Site 23
T318
H
R
E
P
P
P
E
T
P
D
I
N
Q
L
P
Site 24
S368
F
W
K
Q
L
D
L
S
S
R
Q
Q
V
T
D
Site 25
S383
E
L
L
E
K
I
A
S
R
S
Q
N
I
I
E
Site 26
S385
L
E
K
I
A
S
R
S
Q
N
I
I
E
I
N
Site 27
Y417
K
C
P
G
L
L
R
Y
T
A
Y
R
C
K
Q
Site 28
T418
C
P
G
L
L
R
Y
T
A
Y
R
C
K
Q
L
Site 29
Y420
G
L
L
R
Y
T
A
Y
R
C
K
Q
L
S
D
Site 30
S429
C
K
Q
L
S
D
T
S
I
I
A
V
A
S
H
Site 31
T452
V
G
N
Q
D
K
L
T
D
E
G
L
K
Q
L
Site 32
S461
E
G
L
K
Q
L
G
S
K
C
R
E
L
K
D
Site 33
Y475
D
I
H
F
G
Q
C
Y
K
I
S
D
E
G
M
Site 34
Y496
C
L
K
L
Q
R
I
Y
M
Q
E
N
K
L
V
Site 35
S507
N
K
L
V
T
D
Q
S
V
K
A
F
A
E
H
Site 36
Y520
E
H
C
P
E
L
Q
Y
V
G
F
M
G
C
S
Site 37
T537
S
K
G
V
I
H
L
T
K
L
R
N
L
S
S
Site 38
S543
L
T
K
L
R
N
L
S
S
L
D
L
R
H
I
Site 39
S544
T
K
L
R
N
L
S
S
L
D
L
R
H
I
T
Site 40
T551
S
L
D
L
R
H
I
T
E
L
D
N
E
T
V
Site 41
T557
I
T
E
L
D
N
E
T
V
M
E
I
V
K
R
Site 42
S569
V
K
R
C
K
N
L
S
S
L
N
L
C
L
N
Site 43
Y598
G
Q
N
L
K
E
L
Y
L
V
S
C
K
I
T
Site 44
S642
A
T
L
I
A
Q
S
S
K
S
L
R
Y
L
G
Site 45
Y668
V
E
Q
L
V
Q
Q
Y
P
H
I
T
F
S
T
Site 46
T672
V
Q
Q
Y
P
H
I
T
F
S
T
V
L
Q
D
Site 47
Y688
K
R
T
L
E
R
A
Y
Q
M
G
W
T
P
N
Site 48
T693
R
A
Y
Q
M
G
W
T
P
N
M
S
A
A
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation