PhosphoNET

           
Protein Info 
   
Short Name:  NKX1-2
Full Name: 
Alias:  Homeobox protein SAX-1;NKX-1.1
Type: 
Mass (Da):  34708
Number AA:  332
UniProt ID:  Q9UD57
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S14GGAKAAPSHHKISFS
Site 2S21SHHKISFSVLDILDP
Site 3S49APREARKSLAEVEAG
Site 4S60VEAGKDASSRDPVRQ
Site 5S61EAGKDASSRDPVRQL
Site 6T70DPVRQLETPGQGFAA
Site 7S78PGQGFAASLLTRQAH
Site 8S90QAHPHHSSDARDAAG
Site 9S104GPGAGQASPLEGSEA
Site 10S149APAGALASGEPCEDG
Site 11S163GGGGPVRSPPGSPGS
Site 12S167PVRSPPGSPGSPRPR
Site 13S170SPPGSPGSPRPRRRR
Site 14T190AKPRRARTAFTYEQL
Site 15Y194RARTAFTYEQLVALE
Site 16T207LENKFRATRYLSVCE
Site 17Y209NKFRATRYLSVCERL
Site 18S211FRATRYLSVCERLNL
Site 19S221ERLNLALSLSLTETQ
Site 20S271GGGGGGGSGGSPGPP
Site 21S274GGGGSGGSPGPPGTG
Site 22T287TGALHFQTFPSYSAA
Site 23Y328PSYLTPFYAPRL___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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