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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
REV1
Full Name:
Alias:
Alpha integrin-binding protein 80;Rev1-like terminal deoxycytidyl transferase
Type:
Mass (Da):
138248
Number AA:
1251
UniProt ID:
Q9UBZ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S35
K
L
E
E
Q
F
R
S
D
A
A
M
Q
K
D
Site 2
T44
A
A
M
Q
K
D
G
T
S
S
T
I
F
S
G
Site 3
S45
A
M
Q
K
D
G
T
S
S
T
I
F
S
G
V
Site 4
S46
M
Q
K
D
G
T
S
S
T
I
F
S
G
V
A
Site 5
Y59
V
A
I
Y
V
N
G
Y
T
D
P
S
A
E
E
Site 6
S63
V
N
G
Y
T
D
P
S
A
E
E
L
R
K
L
Site 7
Y78
M
M
L
H
G
G
Q
Y
H
V
Y
Y
S
R
S
Site 8
Y81
H
G
G
Q
Y
H
V
Y
Y
S
R
S
K
T
T
Site 9
Y82
G
G
Q
Y
H
V
Y
Y
S
R
S
K
T
T
H
Site 10
T87
V
Y
Y
S
R
S
K
T
T
H
I
I
A
T
N
Site 11
Y126
K
A
G
R
L
L
S
Y
I
P
Y
Q
L
Y
T
Site 12
Y129
R
L
L
S
Y
I
P
Y
Q
L
Y
T
K
Q
S
Site 13
Y132
S
Y
I
P
Y
Q
L
Y
T
K
Q
S
S
V
Q
Site 14
T133
Y
I
P
Y
Q
L
Y
T
K
Q
S
S
V
Q
K
Site 15
S136
Y
Q
L
Y
T
K
Q
S
S
V
Q
K
G
L
S
Site 16
S137
Q
L
Y
T
K
Q
S
S
V
Q
K
G
L
S
F
Site 17
S143
S
S
V
Q
K
G
L
S
F
N
P
V
C
R
P
Site 18
S158
E
D
P
L
P
G
P
S
N
I
A
K
Q
L
N
Site 19
S199
E
D
E
N
N
D
F
S
F
V
D
L
E
Q
T
Site 20
S207
F
V
D
L
E
Q
T
S
P
G
R
K
Q
N
G
Site 21
S221
G
I
P
H
P
R
G
S
T
A
I
F
N
G
H
Site 22
T222
I
P
H
P
R
G
S
T
A
I
F
N
G
H
T
Site 23
T229
T
A
I
F
N
G
H
T
P
S
S
N
G
A
L
Site 24
S231
I
F
N
G
H
T
P
S
S
N
G
A
L
K
T
Site 25
S232
F
N
G
H
T
P
S
S
N
G
A
L
K
T
Q
Site 26
T238
S
S
N
G
A
L
K
T
Q
D
C
L
V
P
M
Site 27
S254
N
S
V
A
S
R
L
S
P
A
F
S
Q
E
E
Site 28
S258
S
R
L
S
P
A
F
S
Q
E
E
D
K
A
E
Site 29
S267
E
E
D
K
A
E
K
S
S
T
D
F
R
D
C
Site 30
T269
D
K
A
E
K
S
S
T
D
F
R
D
C
T
L
Site 31
T275
S
T
D
F
R
D
C
T
L
Q
Q
L
Q
Q
S
Site 32
S282
T
L
Q
Q
L
Q
Q
S
T
R
N
T
D
A
L
Site 33
T286
L
Q
Q
S
T
R
N
T
D
A
L
R
N
P
H
Site 34
T295
A
L
R
N
P
H
R
T
N
S
F
S
L
S
P
Site 35
S297
R
N
P
H
R
T
N
S
F
S
L
S
P
L
H
Site 36
S299
P
H
R
T
N
S
F
S
L
S
P
L
H
S
N
Site 37
S301
R
T
N
S
F
S
L
S
P
L
H
S
N
T
K
Site 38
S305
F
S
L
S
P
L
H
S
N
T
K
I
N
G
A
Site 39
S315
K
I
N
G
A
H
H
S
T
V
Q
G
P
S
S
Site 40
T316
I
N
G
A
H
H
S
T
V
Q
G
P
S
S
T
Site 41
S321
H
S
T
V
Q
G
P
S
S
T
K
S
T
S
S
Site 42
S322
S
T
V
Q
G
P
S
S
T
K
S
T
S
S
V
Site 43
T323
T
V
Q
G
P
S
S
T
K
S
T
S
S
V
S
Site 44
S325
Q
G
P
S
S
T
K
S
T
S
S
V
S
T
F
Site 45
T326
G
P
S
S
T
K
S
T
S
S
V
S
T
F
S
Site 46
S327
P
S
S
T
K
S
T
S
S
V
S
T
F
S
K
Site 47
S328
S
S
T
K
S
T
S
S
V
S
T
F
S
K
A
Site 48
T331
K
S
T
S
S
V
S
T
F
S
K
A
A
P
S
Site 49
S333
T
S
S
V
S
T
F
S
K
A
A
P
S
V
P
Site 50
S338
T
F
S
K
A
A
P
S
V
P
S
K
P
S
D
Site 51
S344
P
S
V
P
S
K
P
S
D
C
N
F
I
S
N
Site 52
T374
E
L
T
E
F
V
N
T
L
Q
R
Q
S
N
G
Site 53
S379
V
N
T
L
Q
R
Q
S
N
G
I
F
P
G
R
Site 54
T394
E
K
L
K
K
M
K
T
G
R
S
A
L
V
V
Site 55
S397
K
K
M
K
T
G
R
S
A
L
V
V
T
D
T
Site 56
S408
V
T
D
T
G
D
M
S
V
L
N
S
P
R
H
Site 57
S412
G
D
M
S
V
L
N
S
P
R
H
Q
S
C
I
Site 58
T447
K
G
K
P
V
A
V
T
S
N
R
G
T
G
R
Site 59
S448
G
K
P
V
A
V
T
S
N
R
G
T
G
R
A
Site 60
T452
A
V
T
S
N
R
G
T
G
R
A
P
L
R
P
Site 61
Y470
P
Q
L
E
W
Q
Y
Y
Q
N
K
I
L
K
G
Site 62
S485
K
A
A
D
I
P
D
S
S
L
W
E
N
P
D
Site 63
S486
A
A
D
I
P
D
S
S
L
W
E
N
P
D
S
Site 64
S493
S
L
W
E
N
P
D
S
A
Q
A
N
G
I
D
Site 65
S501
A
Q
A
N
G
I
D
S
V
L
S
R
A
E
I
Site 66
S510
L
S
R
A
E
I
A
S
C
S
Y
E
A
R
Q
Site 67
S512
R
A
E
I
A
S
C
S
Y
E
A
R
Q
L
G
Site 68
Y541
P
N
L
Q
A
V
P
Y
D
F
H
A
Y
K
E
Site 69
Y546
V
P
Y
D
F
H
A
Y
K
E
V
A
Q
T
L
Site 70
T552
A
Y
K
E
V
A
Q
T
L
Y
E
T
L
A
S
Site 71
Y554
K
E
V
A
Q
T
L
Y
E
T
L
A
S
Y
T
Site 72
T556
V
A
Q
T
L
Y
E
T
L
A
S
Y
T
H
N
Site 73
S559
T
L
Y
E
T
L
A
S
Y
T
H
N
I
E
A
Site 74
S568
T
H
N
I
E
A
V
S
C
D
E
A
L
V
D
Site 75
T586
I
L
A
E
T
K
L
T
P
D
E
F
A
N
A
Site 76
T602
R
M
E
I
K
D
Q
T
K
C
A
A
S
V
G
Site 77
S607
D
Q
T
K
C
A
A
S
V
G
I
G
S
N
I
Site 78
T621
I
L
L
A
R
M
A
T
R
K
A
K
P
D
G
Site 79
Y630
K
A
K
P
D
G
Q
Y
H
L
K
P
E
E
V
Site 80
S655
N
L
P
G
V
G
H
S
M
E
S
K
L
A
S
Site 81
Y673
K
T
C
G
D
L
Q
Y
M
T
M
A
K
L
Q
Site 82
T687
Q
K
E
F
G
P
K
T
G
Q
M
L
Y
R
F
Site 83
Y692
P
K
T
G
Q
M
L
Y
R
F
C
R
G
L
D
Site 84
S711
R
T
E
K
E
R
K
S
V
S
A
E
I
N
Y
Site 85
Y718
S
V
S
A
E
I
N
Y
G
I
R
F
T
Q
P
Site 86
T723
I
N
Y
G
I
R
F
T
Q
P
K
E
A
E
A
Site 87
S734
E
A
E
A
F
L
L
S
L
S
E
E
I
Q
R
Site 88
S736
E
A
F
L
L
S
L
S
E
E
I
Q
R
R
L
Site 89
T746
I
Q
R
R
L
E
A
T
G
M
K
G
K
R
L
Site 90
T754
G
M
K
G
K
R
L
T
L
K
I
M
V
R
K
Site 91
T785
D
N
I
A
R
T
V
T
L
D
Q
A
T
D
N
Site 92
S832
V
P
T
N
L
N
P
S
T
C
P
S
R
P
S
Site 93
T833
P
T
N
L
N
P
S
T
C
P
S
R
P
S
V
Site 94
S836
L
N
P
S
T
C
P
S
R
P
S
V
Q
S
S
Site 95
S839
S
T
C
P
S
R
P
S
V
Q
S
S
H
F
P
Site 96
S842
P
S
R
P
S
V
Q
S
S
H
F
P
S
G
S
Site 97
S843
S
R
P
S
V
Q
S
S
H
F
P
S
G
S
Y
Site 98
S847
V
Q
S
S
H
F
P
S
G
S
Y
S
V
R
D
Site 99
S849
S
S
H
F
P
S
G
S
Y
S
V
R
D
V
F
Site 100
S851
H
F
P
S
G
S
Y
S
V
R
D
V
F
Q
V
Site 101
S864
Q
V
Q
K
A
K
K
S
T
E
E
E
H
K
E
Site 102
T889
S
S
A
S
R
T
C
T
F
L
P
P
F
P
A
Site 103
S901
F
P
A
H
L
P
T
S
P
D
T
N
K
A
E
Site 104
T904
H
L
P
T
S
P
D
T
N
K
A
E
S
S
G
Site 105
T918
G
K
W
N
G
L
H
T
P
V
S
V
Q
S
R
Site 106
S921
N
G
L
H
T
P
V
S
V
Q
S
R
L
N
L
Site 107
S929
V
Q
S
R
L
N
L
S
I
E
V
P
S
P
S
Site 108
S934
N
L
S
I
E
V
P
S
P
S
Q
L
D
Q
S
Site 109
S936
S
I
E
V
P
S
P
S
Q
L
D
Q
S
V
L
Site 110
S941
S
P
S
Q
L
D
Q
S
V
L
E
A
L
P
P
Site 111
S999
Q
I
P
E
P
Q
E
S
N
S
D
A
G
I
N
Site 112
S1001
P
E
P
Q
E
S
N
S
D
A
G
I
N
L
I
Site 113
S1046
R
Q
R
Q
G
E
N
S
T
H
Q
Q
S
A
S
Site 114
S1051
E
N
S
T
H
Q
Q
S
A
S
A
S
V
P
K
Site 115
S1053
S
T
H
Q
Q
S
A
S
A
S
V
P
K
N
P
Site 116
S1055
H
Q
Q
S
A
S
A
S
V
P
K
N
P
L
L
Site 117
S1082
K
K
K
K
T
I
G
S
P
K
R
I
Q
S
P
Site 118
S1088
G
S
P
K
R
I
Q
S
P
L
N
N
K
L
L
Site 119
S1097
L
N
N
K
L
L
N
S
P
A
K
T
L
P
G
Site 120
S1108
T
L
P
G
A
C
G
S
P
Q
K
L
I
D
G
Site 121
S1132
E
K
P
L
E
E
L
S
A
S
T
S
G
V
P
Site 122
S1136
E
E
L
S
A
S
T
S
G
V
P
G
L
S
S
Site 123
S1142
T
S
G
V
P
G
L
S
S
L
Q
S
D
P
A
Site 124
S1143
S
G
V
P
G
L
S
S
L
Q
S
D
P
A
G
Site 125
S1146
P
G
L
S
S
L
Q
S
D
P
A
G
C
V
R
Site 126
T1170
V
E
F
N
D
V
K
T
L
L
R
E
W
I
T
Site 127
T1178
L
L
R
E
W
I
T
T
I
S
D
P
M
E
E
Site 128
S1180
R
E
W
I
T
T
I
S
D
P
M
E
E
D
I
Site 129
Y1212
K
L
D
L
V
I
K
Y
M
K
R
L
M
Q
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation