KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
THAP10
Full Name:
THAP domain-containing protein 10
Alias:
tha10; thap domain containing 10; thap10
Type:
Mass (Da):
28351
Number AA:
257
UniProt ID:
Q9P2Z0
International Prot ID:
IPI00024542
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
H
C
G
N
T
T
K
S
G
K
S
L
F
R
F
Site 2
S19
N
T
T
K
S
G
K
S
L
F
R
F
P
K
D
Site 3
Y45
R
G
C
R
A
D
W
Y
G
G
N
D
R
S
V
Site 4
S67
P
A
C
F
D
V
S
S
V
I
Q
K
N
L
R
Site 5
S76
I
Q
K
N
L
R
F
S
Q
R
L
R
L
V
A
Site 6
T88
L
V
A
G
A
V
P
T
L
H
R
V
P
A
P
Site 7
T111
D
Q
A
G
R
L
D
T
R
G
E
L
Q
A
A
Site 8
S121
E
L
Q
A
A
R
H
S
E
A
A
P
G
P
V
Site 9
S129
E
A
A
P
G
P
V
S
C
T
R
P
R
A
G
Site 10
S142
A
G
K
Q
A
A
A
S
Q
I
T
C
E
N
E
Site 11
T153
C
E
N
E
L
V
Q
T
Q
P
H
A
D
N
P
Site 12
S161
Q
P
H
A
D
N
P
S
N
T
V
T
S
V
P
Site 13
T163
H
A
D
N
P
S
N
T
V
T
S
V
P
T
H
Site 14
T165
D
N
P
S
N
T
V
T
S
V
P
T
H
C
E
Site 15
S179
E
E
G
P
V
H
K
S
T
Q
I
S
L
K
R
Site 16
T180
E
G
P
V
H
K
S
T
Q
I
S
L
K
R
P
Site 17
S183
V
H
K
S
T
Q
I
S
L
K
R
P
R
H
R
Site 18
S191
L
K
R
P
R
H
R
S
V
G
I
Q
A
K
V
Site 19
T209
G
K
R
L
C
N
A
T
T
Q
T
E
E
L
W
Site 20
T210
K
R
L
C
N
A
T
T
Q
T
E
E
L
W
S
Site 21
S217
T
Q
T
E
E
L
W
S
R
T
S
S
L
F
D
Site 22
S220
E
E
L
W
S
R
T
S
S
L
F
D
I
Y
S
Site 23
S221
E
L
W
S
R
T
S
S
L
F
D
I
Y
S
S
Site 24
Y226
T
S
S
L
F
D
I
Y
S
S
D
S
E
T
D
Site 25
S227
S
S
L
F
D
I
Y
S
S
D
S
E
T
D
T
Site 26
S228
S
L
F
D
I
Y
S
S
D
S
E
T
D
T
D
Site 27
S230
F
D
I
Y
S
S
D
S
E
T
D
T
D
W
D
Site 28
T232
I
Y
S
S
D
S
E
T
D
T
D
W
D
I
K
Site 29
T234
S
S
D
S
E
T
D
T
D
W
D
I
K
S
E
Site 30
S240
D
T
D
W
D
I
K
S
E
Q
S
D
L
S
Y
Site 31
S246
K
S
E
Q
S
D
L
S
Y
M
A
V
Q
V
K
Site 32
Y247
S
E
Q
S
D
L
S
Y
M
A
V
Q
V
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation