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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR8
Full Name:
WD repeat-containing protein 8
Alias:
Type:
Mass (Da):
51588
Number AA:
460
UniProt ID:
Q9P2S5
International Prot ID:
IPI00293015
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
S
S
L
L
C
K
F
S
P
D
G
K
Y
L
A
Site 2
Y22
K
F
S
P
D
G
K
Y
L
A
S
C
V
Q
Y
Site 3
S97
G
S
A
G
L
V
A
S
C
W
S
P
D
G
R
Site 4
T109
D
G
R
H
I
L
N
T
T
E
F
H
L
R
I
Site 5
T117
T
E
F
H
L
R
I
T
V
W
S
L
C
T
K
Site 6
S120
H
L
R
I
T
V
W
S
L
C
T
K
S
V
S
Site 7
T123
I
T
V
W
S
L
C
T
K
S
V
S
Y
I
K
Site 8
S125
V
W
S
L
C
T
K
S
V
S
Y
I
K
Y
P
Site 9
Y128
L
C
T
K
S
V
S
Y
I
K
Y
P
K
A
C
Site 10
Y131
K
S
V
S
Y
I
K
Y
P
K
A
C
L
Q
G
Site 11
T140
K
A
C
L
Q
G
I
T
F
T
R
D
G
R
Y
Site 12
Y147
T
F
T
R
D
G
R
Y
M
A
L
A
E
R
R
Site 13
Y159
E
R
R
D
C
K
D
Y
V
S
I
F
V
C
S
Site 14
T176
Q
L
L
R
H
F
D
T
D
T
Q
D
L
T
G
Site 15
T178
L
R
H
F
D
T
D
T
Q
D
L
T
G
I
E
Site 16
T182
D
T
D
T
Q
D
L
T
G
I
E
W
A
P
N
Site 17
S215
S
L
D
G
R
L
L
S
T
Y
S
A
Y
E
W
Site 18
T216
L
D
G
R
L
L
S
T
Y
S
A
Y
E
W
S
Site 19
Y217
D
G
R
L
L
S
T
Y
S
A
Y
E
W
S
L
Site 20
S218
G
R
L
L
S
T
Y
S
A
Y
E
W
S
L
G
Site 21
S228
E
W
S
L
G
I
K
S
V
A
W
S
P
S
S
Site 22
S281
V
Y
K
E
A
E
K
S
P
Q
L
G
L
G
C
Site 23
S303
A
G
A
G
P
L
P
S
S
E
S
K
Y
E
I
Site 24
S304
G
A
G
P
L
P
S
S
E
S
K
Y
E
I
A
Site 25
S306
G
P
L
P
S
S
E
S
K
Y
E
I
A
S
V
Site 26
Y308
L
P
S
S
E
S
K
Y
E
I
A
S
V
P
V
Site 27
S312
E
S
K
Y
E
I
A
S
V
P
V
S
L
Q
T
Site 28
T319
S
V
P
V
S
L
Q
T
L
K
P
V
T
D
R
Site 29
T324
L
Q
T
L
K
P
V
T
D
R
A
N
P
K
I
Site 30
S339
G
I
G
M
L
A
F
S
P
D
S
Y
F
L
A
Site 31
S342
M
L
A
F
S
P
D
S
Y
F
L
A
T
R
N
Site 32
Y343
L
A
F
S
P
D
S
Y
F
L
A
T
R
N
D
Site 33
S407
W
S
P
A
G
C
M
S
V
Q
V
P
G
E
G
Site 34
S429
C
W
H
L
S
G
D
S
M
A
L
L
S
K
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation