KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KIAA1305
Full Name:
Protein NYNRIN
Alias:
CGIN1; Cousin of GIN1; FLJ11811; K1305; NYN domain and retroviral integrase containing
Type:
Unknown function
Mass (Da):
208366
Number AA:
1898
UniProt ID:
Q9P2P1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0015074
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
V
K
L
N
A
F
Q
S
R
P
D
T
P
Y
F
Site 2
T48
A
F
Q
S
R
P
D
T
P
Y
F
W
L
Q
L
Site 3
Y50
Q
S
R
P
D
T
P
Y
F
W
L
Q
L
E
G
Site 4
Y68
N
M
G
K
A
K
E
Y
L
K
G
L
C
S
P
Site 5
S74
E
Y
L
K
G
L
C
S
P
E
L
W
K
E
V
Site 6
Y83
E
L
W
K
E
V
R
Y
P
P
I
L
H
C
A
Site 7
T130
L
T
E
S
F
I
M
T
Q
N
W
L
E
E
L
Site 8
T150
W
G
P
A
P
L
L
T
P
R
G
I
W
E
A
Site 9
S207
E
D
I
I
E
W
L
S
R
F
G
I
S
D
S
Site 10
S212
W
L
S
R
F
G
I
S
D
S
H
S
D
P
E
Site 11
S214
S
R
F
G
I
S
D
S
H
S
D
P
E
V
L
Site 12
S236
K
E
A
P
A
M
V
S
V
G
E
S
P
G
P
Site 13
T249
G
P
F
V
D
M
G
T
L
Q
N
R
G
P
E
Site 14
S258
Q
N
R
G
P
E
N
S
K
R
L
S
S
L
G
Site 15
S262
P
E
N
S
K
R
L
S
S
L
G
A
T
G
S
Site 16
S263
E
N
S
K
R
L
S
S
L
G
A
T
G
S
L
Site 17
S275
G
S
L
I
T
A
Q
S
T
P
Q
E
A
A
N
Site 18
T276
S
L
I
T
A
Q
S
T
P
Q
E
A
A
N
Q
Site 19
S289
N
Q
L
V
R
V
G
S
N
N
Q
D
G
M
D
Site 20
S297
N
N
Q
D
G
M
D
S
A
Q
E
E
G
T
V
Site 21
T303
D
S
A
Q
E
E
G
T
V
Q
A
T
S
S
Q
Site 22
S308
E
G
T
V
Q
A
T
S
S
Q
D
S
T
N
H
Site 23
S309
G
T
V
Q
A
T
S
S
Q
D
S
T
N
H
T
Site 24
S312
Q
A
T
S
S
Q
D
S
T
N
H
T
Q
A
L
Site 25
T313
A
T
S
S
Q
D
S
T
N
H
T
Q
A
L
L
Site 26
T316
S
Q
D
S
T
N
H
T
Q
A
L
L
K
Q
R
Site 27
S426
K
E
L
A
P
L
P
S
A
E
S
P
A
G
R
Site 28
S429
A
P
L
P
S
A
E
S
P
A
G
R
P
D
G
Site 29
S453
N
C
P
R
P
E
I
S
P
K
V
T
S
L
L
Site 30
T484
P
Q
I
G
P
P
L
T
S
T
P
Q
L
Q
A
Site 31
T486
I
G
P
P
L
T
S
T
P
Q
L
Q
A
G
G
Site 32
S500
G
E
P
G
D
Q
G
S
M
Q
L
D
F
K
G
Site 33
T530
P
V
A
Q
G
G
L
T
D
Q
S
V
P
G
A
Site 34
S533
Q
G
G
L
T
D
Q
S
V
P
G
A
Q
T
V
Site 35
T539
Q
S
V
P
G
A
Q
T
V
P
E
T
L
K
V
Site 36
S559
V
P
K
A
E
N
P
S
R
T
Q
V
P
S
A
Site 37
T561
K
A
E
N
P
S
R
T
Q
V
P
S
A
A
P
Site 38
S565
P
S
R
T
Q
V
P
S
A
A
P
K
L
P
T
Site 39
T593
P
E
V
P
L
A
P
T
K
P
T
A
Q
L
M
Site 40
T621
V
A
Q
V
E
P
T
T
P
K
T
P
Q
A
Q
Site 41
T624
V
E
P
T
T
P
K
T
P
Q
A
Q
K
M
P
Site 42
S636
K
M
P
V
A
K
T
S
P
A
G
P
K
T
P
Site 43
T642
T
S
P
A
G
P
K
T
P
K
A
Q
A
G
P
Site 44
S654
A
G
P
A
A
T
V
S
K
A
P
A
A
S
K
Site 45
S660
V
S
K
A
P
A
A
S
K
A
P
A
A
P
K
Site 46
T671
A
A
P
K
V
P
V
T
P
R
V
S
R
A
P
Site 47
S675
V
P
V
T
P
R
V
S
R
A
P
K
T
P
A
Site 48
T680
R
V
S
R
A
P
K
T
P
A
A
Q
K
V
P
Site 49
S701
L
D
V
A
R
L
L
S
E
V
Q
P
T
S
R
Site 50
S710
V
Q
P
T
S
R
A
S
V
S
L
L
K
G
Q
Site 51
S712
P
T
S
R
A
S
V
S
L
L
K
G
Q
G
Q
Site 52
S727
A
G
R
Q
G
P
Q
S
S
G
T
L
A
L
S
Site 53
S728
G
R
Q
G
P
Q
S
S
G
T
L
A
L
S
S
Site 54
T730
Q
G
P
Q
S
S
G
T
L
A
L
S
S
K
H
Site 55
S734
S
S
G
T
L
A
L
S
S
K
H
Q
F
Q
M
Site 56
S735
S
G
T
L
A
L
S
S
K
H
Q
F
Q
M
E
Site 57
S763
P
R
H
L
Q
A
N
S
T
V
T
S
F
Q
R
Site 58
T764
R
H
L
Q
A
N
S
T
V
T
S
F
Q
R
Y
Site 59
S767
Q
A
N
S
T
V
T
S
F
Q
R
Y
H
E
A
Site 60
T777
R
Y
H
E
A
L
N
T
P
F
E
L
N
L
S
Site 61
S784
T
P
F
E
L
N
L
S
G
E
P
G
N
Q
G
Site 62
T833
N
R
G
H
R
E
V
T
V
F
V
P
T
W
Q
Site 63
S850
K
N
R
R
V
R
E
S
H
F
L
T
K
L
H
Site 64
T854
V
R
E
S
H
F
L
T
K
L
H
S
L
K
M
Site 65
S863
L
H
S
L
K
M
L
S
I
T
P
S
Q
L
E
Site 66
T865
S
L
K
M
L
S
I
T
P
S
Q
L
E
N
G
Site 67
S867
K
M
L
S
I
T
P
S
Q
L
E
N
G
K
K
Site 68
Y878
N
G
K
K
I
T
T
Y
D
Y
R
F
M
V
K
Site 69
Y880
K
K
I
T
T
Y
D
Y
R
F
M
V
K
L
A
Site 70
S906
Q
I
H
I
L
M
N
S
S
K
K
L
M
V
K
Site 71
T939
P
L
G
R
D
G
P
T
L
D
E
F
L
K
K
Site 72
T952
K
K
P
N
R
L
D
T
D
I
G
N
F
L
K
Site 73
T963
N
F
L
K
V
W
K
T
L
P
P
S
S
A
S
Site 74
S967
V
W
K
T
L
P
P
S
S
A
S
V
T
E
L
Site 75
S968
W
K
T
L
P
P
S
S
A
S
V
T
E
L
S
Site 76
S970
T
L
P
P
S
S
A
S
V
T
E
L
S
D
D
Site 77
T972
P
P
S
S
A
S
V
T
E
L
S
D
D
A
D
Site 78
S975
S
A
S
V
T
E
L
S
D
D
A
D
S
G
P
Site 79
S980
E
L
S
D
D
A
D
S
G
P
L
E
S
L
P
Site 80
T1010
E
Q
R
Q
G
Q
G
T
Q
K
A
A
E
E
D
Site 81
S1021
A
E
E
D
D
L
D
S
S
L
A
S
V
F
R
Site 82
S1022
E
E
D
D
L
D
S
S
L
A
S
V
F
R
V
Site 83
S1043
E
E
I
L
R
C
L
S
L
H
D
P
P
D
G
Site 84
Y1111
H
R
D
A
I
P
D
Y
E
A
L
V
G
P
L
Site 85
S1120
A
L
V
G
P
L
H
S
L
L
K
Q
K
P
D
Site 86
S1180
A
I
L
H
Q
E
H
S
G
R
K
H
P
I
A
Site 87
T1189
R
K
H
P
I
A
Y
T
S
K
P
L
L
P
D
Site 88
S1190
K
H
P
I
A
Y
T
S
K
P
L
L
P
D
E
Site 89
S1199
P
L
L
P
D
E
E
S
Q
G
P
Q
S
G
G
Site 90
S1204
E
E
S
Q
G
P
Q
S
G
G
D
S
P
Y
A
Site 91
S1208
G
P
Q
S
G
G
D
S
P
Y
A
V
A
W
A
Site 92
Y1210
Q
S
G
G
D
S
P
Y
A
V
A
W
A
L
K
Site 93
T1239
L
S
Y
A
S
R
T
T
A
D
P
E
V
R
E
Site 94
S1251
V
R
E
G
R
R
V
S
K
A
W
L
I
R
W
Site 95
S1259
K
A
W
L
I
R
W
S
L
L
V
Q
D
K
G
Site 96
T1286
L
G
E
N
R
L
L
T
P
A
A
S
M
P
R
Site 97
S1290
R
L
L
T
P
A
A
S
M
P
R
F
F
Q
V
Site 98
S1340
S
P
T
S
P
P
V
S
L
S
F
S
C
S
P
Site 99
S1342
T
S
P
P
V
S
L
S
F
S
C
S
P
Y
T
Site 100
S1344
P
P
V
S
L
S
F
S
C
S
P
Y
T
P
T
Site 101
Y1348
L
S
F
S
C
S
P
Y
T
P
T
Y
A
H
L
Site 102
T1349
S
F
S
C
S
P
Y
T
P
T
Y
A
H
L
A
Site 103
S1399
W
R
A
R
G
F
L
S
S
D
G
A
P
L
P
Site 104
S1400
R
A
R
G
F
L
S
S
D
G
A
P
L
P
H
Site 105
S1419
S
Y
I
I
S
L
T
S
G
L
S
S
L
P
F
Site 106
S1422
I
S
L
T
S
G
L
S
S
L
P
F
I
Y
R
Site 107
T1430
S
L
P
F
I
Y
R
T
S
Y
R
G
S
L
F
Site 108
S1435
Y
R
T
S
Y
R
G
S
L
F
A
V
T
V
D
Site 109
T1440
R
G
S
L
F
A
V
T
V
D
T
L
A
K
Q
Site 110
T1443
L
F
A
V
T
V
D
T
L
A
K
Q
G
A
Q
Site 111
S1457
Q
G
G
G
Q
W
W
S
L
P
K
D
V
P
A
Site 112
T1466
P
K
D
V
P
A
P
T
V
S
P
H
A
M
G
Site 113
S1468
D
V
P
A
P
T
V
S
P
H
A
M
G
K
R
Site 114
S1502
L
Q
A
G
Q
K
L
S
G
S
S
P
F
S
S
Site 115
S1504
A
G
Q
K
L
S
G
S
S
P
F
S
S
A
F
Site 116
S1505
G
Q
K
L
S
G
S
S
P
F
S
S
A
F
N
Site 117
S1508
L
S
G
S
S
P
F
S
S
A
F
N
S
L
S
Site 118
S1509
S
G
S
S
P
F
S
S
A
F
N
S
L
S
L
Site 119
S1513
P
F
S
S
A
F
N
S
L
S
L
D
K
E
S
Site 120
S1515
S
S
A
F
N
S
L
S
L
D
K
E
S
G
L
Site 121
Y1563
H
Q
R
P
E
E
T
Y
K
K
L
R
L
L
G
Site 122
S1604
S
E
L
K
V
I
E
S
P
W
P
L
R
S
T
Site 123
S1610
E
S
P
W
P
L
R
S
T
A
P
W
S
N
L
Site 124
T1611
S
P
W
P
L
R
S
T
A
P
W
S
N
L
Q
Site 125
T1626
I
E
V
V
G
P
V
T
I
S
E
E
G
H
K
Site 126
S1628
V
V
G
P
V
T
I
S
E
E
G
H
K
H
V
Site 127
S1705
G
A
Q
V
A
S
L
S
R
D
L
Q
F
P
C
Site 128
S1752
H
L
A
F
R
A
S
S
T
D
A
T
P
F
K
Site 129
T1756
R
A
S
S
T
D
A
T
P
F
K
V
L
T
G
Site 130
T1762
A
T
P
F
K
V
L
T
G
G
E
S
R
L
T
Site 131
T1769
T
G
G
E
S
R
L
T
E
P
L
W
W
E
M
Site 132
S1777
E
P
L
W
W
E
M
S
S
A
N
I
E
G
L
Site 133
S1821
N
R
R
F
K
R
E
S
Q
E
K
E
W
N
V
Site 134
S1836
G
D
Q
V
L
L
L
S
L
P
R
N
G
S
S
Site 135
S1842
L
S
L
P
R
N
G
S
S
A
K
W
V
G
P
Site 136
S1843
S
L
P
R
N
G
S
S
A
K
W
V
G
P
F
Site 137
Y1861
D
R
L
S
L
S
L
Y
R
I
W
G
F
P
T
Site 138
T1868
Y
R
I
W
G
F
P
T
P
E
K
L
G
C
I
Site 139
Y1876
P
E
K
L
G
C
I
Y
P
S
S
L
M
K
A
Site 140
S1892
A
K
S
G
T
P
L
S
F
K
V
L
E
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation