KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LRP2BP
Full Name:
LRP2-binding protein
Alias:
FLJ44965; LR2BP; LRP2 binding protein
Type:
Adapter protein. Regulates LRP2 function.
Mass (Da):
39780
Number AA:
347
UniProt ID:
Q9P2M1
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
K
L
P
K
N
P
F
Y
A
S
V
S
Q
Y
A
Site 2
S16
P
K
N
P
F
Y
A
S
V
S
Q
Y
A
A
K
Site 3
S18
N
P
F
Y
A
S
V
S
Q
Y
A
A
K
N
Q
Site 4
Y20
F
Y
A
S
V
S
Q
Y
A
A
K
N
Q
K
F
Site 5
Y37
W
K
K
E
K
T
D
Y
T
H
A
N
L
V
D
Site 6
T38
K
K
E
K
T
D
Y
T
H
A
N
L
V
D
K
Site 7
T59
E
R
I
L
K
G
D
T
L
A
Y
F
L
R
G
Site 8
Y62
L
K
G
D
T
L
A
Y
F
L
R
G
Q
L
Y
Site 9
Y69
Y
F
L
R
G
Q
L
Y
F
E
E
G
W
Y
E
Site 10
Y75
L
Y
F
E
E
G
W
Y
E
E
A
L
E
Q
F
Site 11
Y94
E
K
D
H
Q
A
T
Y
Q
L
G
V
M
Y
Y
Site 12
Y100
T
Y
Q
L
G
V
M
Y
Y
D
G
L
G
T
T
Site 13
Y116
D
A
E
K
G
V
D
Y
M
K
K
I
L
D
S
Site 14
S123
Y
M
K
K
I
L
D
S
P
C
P
K
A
R
H
Site 15
Y143
A
Y
N
L
G
R
A
Y
Y
E
G
K
G
V
K
Site 16
Y144
Y
N
L
G
R
A
Y
Y
E
G
K
G
V
K
R
Site 17
S152
E
G
K
G
V
K
R
S
N
E
E
A
E
R
L
Site 18
Y182
A
Q
S
M
L
G
L
Y
Y
S
T
K
E
P
K
Site 19
S184
S
M
L
G
L
Y
Y
S
T
K
E
P
K
E
L
Site 20
Y196
K
E
L
E
K
A
F
Y
W
H
S
E
A
C
G
Site 21
S209
C
G
N
G
N
L
E
S
Q
G
A
L
G
L
M
Site 22
T227
G
Q
G
I
R
Q
D
T
E
A
A
L
Q
C
L
Site 23
Y252
A
Q
G
N
L
V
E
Y
Y
Y
K
M
K
F
F
Site 24
Y253
Q
G
N
L
V
E
Y
Y
Y
K
M
K
F
F
T
Site 25
Y254
G
N
L
V
E
Y
Y
Y
K
M
K
F
F
T
K
Site 26
Y272
F
S
K
R
I
A
D
Y
D
E
V
H
D
I
P
Site 27
T318
L
G
I
T
R
D
E
T
T
A
K
H
Y
Y
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation