PhosphoNET

           
Protein Info 
   
Short Name:  PAK5
Full Name:  Serine/threonine-protein kinase PAK 7
Alias:  EC 2.7.11.1; KIAA1264; P21 protein (Cdc42/Rac)-activated kinase 7; P21-activated kinase 7; PAK 7; PAK-5; PAK7; PAK-7
Type:  EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; PAKB subfamily
Mass (Da):  80745
Number AA:  719
UniProt ID:  Q9P286
International Prot ID:  IPI00001814
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005515  GO:0004674 PhosphoSite+ KinaseNET
Biological Process:  GO:0006468     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12KKKKIEISGPSNFEH
Site 2T23NFEHRVHTGFDPQEQ
Site 3S41GLPQQWHSLLADTAN
Site 4T69IQLAPMKTIVRGNKP
Site 5S81NKPCKETSINGLLED
Site 6S93LEDFDNISVTRSNSL
Site 7T95DFDNISVTRSNSLRK
Site 8S97DNISVTRSNSLRKES
Site 9S99ISVTRSNSLRKESPP
Site 10S104SNSLRKESPPTPDQG
Site 11T107LRKESPPTPDQGASS
Site 12S113PTPDQGASSHGPGHA
Site 13S114TPDQGASSHGPGHAE
Site 14T127AEENGFITFSQYSSE
Site 15S129ENGFITFSQYSSESD
Site 16Y131GFITFSQYSSESDTT
Site 17S133ITFSQYSSESDTTAD
Site 18T137QYSSESDTTADYTTE
Site 19T138YSSESDTTADYTTEK
Site 20Y141ESDTTADYTTEKYRE
Site 21T142SDTTADYTTEKYREK
Site 22Y146ADYTTEKYREKSLYG
Site 23S150TEKYREKSLYGDDLD
Site 24Y152KYREKSLYGDDLDPY
Site 25Y159YGDDLDPYYRGSHAA
Site 26Y160GDDLDPYYRGSHAAK
Site 27S163LDPYYRGSHAAKQNG
Site 28Y182MKHGEAYYSEVKPLK
Site 29S183KHGEAYYSEVKPLKS
Site 30S190SEVKPLKSDFARFSA
Site 31S196KSDFARFSADYHSHL
Site 32Y199FARFSADYHSHLDSL
Site 33S201RFSADYHSHLDSLSK
Site 34S205DYHSHLDSLSKPSEY
Site 35S207HSHLDSLSKPSEYSD
Site 36S210LDSLSKPSEYSDLKW
Site 37S213LSKPSEYSDLKWEYQ
Site 38Y219YSDLKWEYQRASSSS
Site 39S223KWEYQRASSSSPLDY
Site 40S224WEYQRASSSSPLDYS
Site 41S225EYQRASSSSPLDYSF
Site 42S226YQRASSSSPLDYSFQ
Site 43Y230SSSSPLDYSFQFTPS
Site 44S231SSSPLDYSFQFTPSR
Site 45T235LDYSFQFTPSRTAGT
Site 46S237YSFQFTPSRTAGTSG
Site 47S243PSRTAGTSGCSKESL
Site 48S249TSGCSKESLAYSESE
Site 49Y252CSKESLAYSESEWGP
Site 50S253SKESLAYSESEWGPS
Site 51S255ESLAYSESEWGPSLD
Site 52S260SESEWGPSLDDYDRR
Site 53Y264WGPSLDDYDRRPKSS
Site 54S270DYDRRPKSSYLNQTS
Site 55S271YDRRPKSSYLNQTSP
Site 56Y272DRRPKSSYLNQTSPQ
Site 57S277SSYLNQTSPQPTMRQ
Site 58T281NQTSPQPTMRQRSRS
Site 59S286QPTMRQRSRSGSGLQ
Site 60S288TMRQRSRSGSGLQEP
Site 61S290RQRSRSGSGLQEPMM
Site 62T306FGASAFKTHPQGHSY
Site 63Y313THPQGHSYNSYTYPR
Site 64S315PQGHSYNSYTYPRLS
Site 65Y316QGHSYNSYTYPRLSE
Site 66T317GHSYNSYTYPRLSEP
Site 67Y318HSYNSYTYPRLSEPT
Site 68S322SYTYPRLSEPTMCIP
Site 69S341DRAQMVLSPPLSGSD
Site 70S345MVLSPPLSGSDTYPR
Site 71S347LSPPLSGSDTYPRGP
Site 72T349PPLSGSDTYPRGPAK
Site 73Y350PLSGSDTYPRGPAKL
Site 74S360GPAKLPQSQSKSGYS
Site 75S362AKLPQSQSKSGYSSS
Site 76S364LPQSQSKSGYSSSSH
Site 77Y366QSQSKSGYSSSSHQY
Site 78S367SQSKSGYSSSSHQYP
Site 79S368QSKSGYSSSSHQYPS
Site 80S369SKSGYSSSSHQYPSG
Site 81S370KSGYSSSSHQYPSGY
Site 82Y373YSSSSHQYPSGYHKA
Site 83S375SSSHQYPSGYHKATL
Site 84Y377SHQYPSGYHKATLYH
Site 85T381PSGYHKATLYHHPSL
Site 86Y383GYHKATLYHHPSLQS
Site 87S387ATLYHHPSLQSSSQY
Site 88S391HHPSLQSSSQYISTA
Site 89S392HPSLQSSSQYISTAS
Site 90Y394SLQSSSQYISTASYL
Site 91S396QSSSQYISTASYLSS
Site 92T397SSSQYISTASYLSSL
Site 93S403STASYLSSLSLSSST
Site 94S405ASYLSSLSLSSSTYP
Site 95S407YLSSLSLSSSTYPPP
Site 96S408LSSLSLSSSTYPPPS
Site 97S409SSLSLSSSTYPPPSW
Site 98T410SLSLSSSTYPPPSWG
Site 99Y411LSLSSSTYPPPSWGS
Site 100S415SSTYPPPSWGSSSDQ
Site 101S418YPPPSWGSSSDQQPS
Site 102S419PPPSWGSSSDQQPSR
Site 103S420PPSWGSSSDQQPSRV
Site 104S425SSSDQQPSRVSHEQF
Site 105S428DQQPSRVSHEQFRAA
Site 106S441AALQLVVSPGDPREY
Site 107Y448SPGDPREYLANFIKI
Site 108T467TGIVCIATEKHTGKQ
Site 109Y501EVVIMRDYHHDNVVD
Site 110Y510HDNVVDMYSSYLVGD
Site 111S511DNVVDMYSSYLVGDE
Site 112T536GALTDIVTHTRMNEE
Site 113S573HRDIKSDSILLTSDG
Site 114T577KSDSILLTSDGRIKL
Site 115S578SDSILLTSDGRIKLS
Site 116S585SDGRIKLSDFGFCAQ
Site 117S602KEVPKRKSLVGTPYW
Site 118T606KRKSLVGTPYWMAPE
Site 119Y608KSLVGTPYWMAPEVI
Site 120Y620EVISRLPYGTEVDIW
Site 121Y643MIDGEPPYFNEPPLQ
Site 122S658AMRRIRDSLPPRVKD
Site 123S671KDLHKVSSVLRGFLD
Site 124S686LMLVREPSQRATAQE
Site 125T690REPSQRATAQELLGH
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation