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Updated November 2019
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Protein Info
Short Name:
KIAA1462
Full Name:
Uncharacterized protein KIAA1462
Alias:
K1462
Type:
Uncharacterized protein
Mass (Da):
148351
Number AA:
1359
UniProt ID:
Q9P266
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y2
_
_
_
_
_
_
M
Y
S
V
E
D
L
L
I
Site 2
S10
S
V
E
D
L
L
I
S
H
G
Y
K
L
S
R
Site 3
S16
I
S
H
G
Y
K
L
S
R
D
P
P
A
S
R
Site 4
S22
L
S
R
D
P
P
A
S
R
E
D
N
P
K
G
Site 5
T35
K
G
R
Q
A
A
R
T
G
T
R
A
G
Q
G
Site 6
T37
R
Q
A
A
R
T
G
T
R
A
G
Q
G
L
Q
Site 7
T59
A
A
L
A
H
R
K
T
S
A
G
K
G
H
V
Site 8
S60
A
L
A
H
R
K
T
S
A
G
K
G
H
V
S
Site 9
S67
S
A
G
K
G
H
V
S
D
S
E
S
R
R
S
Site 10
S69
G
K
G
H
V
S
D
S
E
S
R
R
S
T
P
Site 11
S71
G
H
V
S
D
S
E
S
R
R
S
T
P
R
G
Site 12
S74
S
D
S
E
S
R
R
S
T
P
R
G
H
G
E
Site 13
T75
D
S
E
S
R
R
S
T
P
R
G
H
G
E
P
Site 14
S84
R
G
H
G
E
P
Q
S
T
S
A
S
R
T
S
Site 15
T85
G
H
G
E
P
Q
S
T
S
A
S
R
T
S
E
Site 16
S86
H
G
E
P
Q
S
T
S
A
S
R
T
S
E
A
Site 17
S88
E
P
Q
S
T
S
A
S
R
T
S
E
A
G
F
Site 18
T90
Q
S
T
S
A
S
R
T
S
E
A
G
F
C
N
Site 19
S91
S
T
S
A
S
R
T
S
E
A
G
F
C
N
Q
Site 20
S101
G
F
C
N
Q
P
P
S
A
W
S
S
H
P
P
Site 21
S104
N
Q
P
P
S
A
W
S
S
H
P
P
T
G
N
Site 22
S105
Q
P
P
S
A
W
S
S
H
P
P
T
G
N
D
Site 23
T109
A
W
S
S
H
P
P
T
G
N
D
Q
A
Y
R
Site 24
Y115
P
T
G
N
D
Q
A
Y
R
R
R
G
R
Q
E
Site 25
S125
R
G
R
Q
E
A
R
S
Q
K
P
R
E
H
E
Site 26
S144
R
G
M
A
Q
A
H
S
L
P
V
H
V
R
E
Site 27
S185
P
A
K
W
Q
N
V
S
L
E
S
W
N
Q
P
Site 28
S200
R
K
L
G
R
Q
M
S
D
G
D
G
E
R
L
Site 29
Y212
E
R
L
F
Q
D
L
Y
P
F
I
Q
G
E
H
Site 30
S223
Q
G
E
H
V
L
N
S
Q
N
K
G
K
S
R
Site 31
S231
Q
N
K
G
K
S
R
S
L
P
R
V
L
S
P
Site 32
S237
R
S
L
P
R
V
L
S
P
E
S
L
S
C
T
Site 33
S240
P
R
V
L
S
P
E
S
L
S
C
T
E
I
P
Site 34
T244
S
P
E
S
L
S
C
T
E
I
P
I
P
L
N
Site 35
S255
I
P
L
N
E
R
H
S
P
K
M
P
P
Y
P
Site 36
Y261
H
S
P
K
M
P
P
Y
P
P
T
C
A
P
N
Site 37
T264
K
M
P
P
Y
P
P
T
C
A
P
N
L
D
S
Site 38
S271
T
C
A
P
N
L
D
S
T
R
N
S
E
K
S
Site 39
T272
C
A
P
N
L
D
S
T
R
N
S
E
K
S
G
Site 40
S275
N
L
D
S
T
R
N
S
E
K
S
G
C
S
A
Site 41
S278
S
T
R
N
S
E
K
S
G
C
S
A
P
F
P
Site 42
S297
G
R
P
L
K
P
P
S
Y
S
S
H
Q
Q
S
Site 43
Y298
R
P
L
K
P
P
S
Y
S
S
H
Q
Q
S
R
Site 44
S299
P
L
K
P
P
S
Y
S
S
H
Q
Q
S
R
G
Site 45
S300
L
K
P
P
S
Y
S
S
H
Q
Q
S
R
G
G
Site 46
S304
S
Y
S
S
H
Q
Q
S
R
G
G
A
D
S
S
Site 47
S310
Q
S
R
G
G
A
D
S
S
D
S
Q
D
S
Q
Site 48
S311
S
R
G
G
A
D
S
S
D
S
Q
D
S
Q
Q
Site 49
S313
G
G
A
D
S
S
D
S
Q
D
S
Q
Q
M
D
Site 50
S316
D
S
S
D
S
Q
D
S
Q
Q
M
D
A
Y
V
Site 51
Y322
D
S
Q
Q
M
D
A
Y
V
P
R
H
E
L
C
Site 52
S331
P
R
H
E
L
C
L
S
D
P
G
L
E
P
P
Site 53
Y340
P
G
L
E
P
P
V
Y
V
P
P
P
S
Y
R
Site 54
S345
P
V
Y
V
P
P
P
S
Y
R
S
P
P
Q
N
Site 55
Y346
V
Y
V
P
P
P
S
Y
R
S
P
P
Q
N
I
Site 56
S348
V
P
P
P
S
Y
R
S
P
P
Q
N
I
P
N
Site 57
Y357
P
Q
N
I
P
N
P
Y
L
E
D
T
V
P
I
Site 58
T361
P
N
P
Y
L
E
D
T
V
P
I
N
V
C
G
Site 59
S371
I
N
V
C
G
G
H
S
Q
Q
Q
S
P
T
E
Site 60
S375
G
G
H
S
Q
Q
Q
S
P
T
E
K
A
G
A
Site 61
S383
P
T
E
K
A
G
A
S
G
Q
P
P
S
G
P
Site 62
S388
G
A
S
G
Q
P
P
S
G
P
P
G
T
G
N
Site 63
T393
P
P
S
G
P
P
G
T
G
N
E
Y
G
V
S
Site 64
Y397
P
P
G
T
G
N
E
Y
G
V
S
P
R
L
P
Site 65
S400
T
G
N
E
Y
G
V
S
P
R
L
P
Q
G
L
Site 66
T415
P
A
H
P
R
P
V
T
A
Y
D
G
F
V
Q
Site 67
Y417
H
P
R
P
V
T
A
Y
D
G
F
V
Q
Y
I
Site 68
Y423
A
Y
D
G
F
V
Q
Y
I
P
F
D
D
P
R
Site 69
S452
D
I
K
L
D
D
K
S
Y
N
S
S
P
V
T
Site 70
Y453
I
K
L
D
D
K
S
Y
N
S
S
P
V
T
A
Site 71
S456
D
D
K
S
Y
N
S
S
P
V
T
A
Q
E
P
Site 72
T459
S
Y
N
S
S
P
V
T
A
Q
E
P
A
H
G
Site 73
S479
G
A
I
W
N
P
Q
S
L
I
P
P
S
G
D
Site 74
S484
P
Q
S
L
I
P
P
S
G
D
E
R
G
L
V
Site 75
S495
R
G
L
V
L
A
D
S
S
P
R
W
L
W
G
Site 76
S496
G
L
V
L
A
D
S
S
P
R
W
L
W
G
Q
Site 77
S532
Q
W
P
D
V
R
G
S
Q
H
G
H
T
G
R
Site 78
T537
R
G
S
Q
H
G
H
T
G
R
Q
V
S
S
P
Site 79
S542
G
H
T
G
R
Q
V
S
S
P
Y
S
Q
G
E
Site 80
S543
H
T
G
R
Q
V
S
S
P
Y
S
Q
G
E
S
Site 81
Y545
G
R
Q
V
S
S
P
Y
S
Q
G
E
S
T
C
Site 82
S546
R
Q
V
S
S
P
Y
S
Q
G
E
S
T
C
E
Site 83
S550
S
P
Y
S
Q
G
E
S
T
C
E
T
Q
T
K
Site 84
T554
Q
G
E
S
T
C
E
T
Q
T
K
L
K
K
F
Site 85
T563
T
K
L
K
K
F
Q
T
G
T
R
T
K
K
S
Site 86
T565
L
K
K
F
Q
T
G
T
R
T
K
K
S
S
K
Site 87
T567
K
F
Q
T
G
T
R
T
K
K
S
S
K
K
K
Site 88
S570
T
G
T
R
T
K
K
S
S
K
K
K
M
N
E
Site 89
S571
G
T
R
T
K
K
S
S
K
K
K
M
N
E
T
Site 90
S589
L
V
S
I
P
V
K
S
E
S
H
L
P
D
R
Site 91
S591
S
I
P
V
K
S
E
S
H
L
P
D
R
D
M
Site 92
S613
S
A
D
Q
K
N
G
S
D
K
S
P
A
L
Q
Site 93
S616
Q
K
N
G
S
D
K
S
P
A
L
Q
E
Q
S
Site 94
S623
S
P
A
L
Q
E
Q
S
L
L
S
M
S
S
T
Site 95
S626
L
Q
E
Q
S
L
L
S
M
S
S
T
D
L
E
Site 96
S628
E
Q
S
L
L
S
M
S
S
T
D
L
E
L
Q
Site 97
S629
Q
S
L
L
S
M
S
S
T
D
L
E
L
Q
A
Site 98
S640
E
L
Q
A
L
T
G
S
M
G
G
R
T
E
F
Site 99
T661
E
P
E
E
D
R
Q
T
N
D
L
S
F
I
H
Site 100
S665
D
R
Q
T
N
D
L
S
F
I
H
L
T
K
H
Site 101
T670
D
L
S
F
I
H
L
T
K
H
R
E
L
K
H
Site 102
S678
K
H
R
E
L
K
H
S
G
S
W
P
G
H
R
Site 103
S680
R
E
L
K
H
S
G
S
W
P
G
H
R
Y
R
Site 104
T691
H
R
Y
R
D
Q
Q
T
Q
T
S
F
S
E
E
Site 105
T693
Y
R
D
Q
Q
T
Q
T
S
F
S
E
E
P
Q
Site 106
S694
R
D
Q
Q
T
Q
T
S
F
S
E
E
P
Q
S
Site 107
S696
Q
Q
T
Q
T
S
F
S
E
E
P
Q
S
S
Q
Site 108
S701
S
F
S
E
E
P
Q
S
S
Q
L
L
P
G
A
Site 109
S702
F
S
E
E
P
Q
S
S
Q
L
L
P
G
A
K
Site 110
S714
G
A
K
L
G
G
P
S
R
A
A
L
S
P
K
Site 111
S719
G
P
S
R
A
A
L
S
P
K
C
S
D
P
A
Site 112
S723
A
A
L
S
P
K
C
S
D
P
A
A
S
E
A
Site 113
T732
P
A
A
S
E
A
Q
T
H
T
A
F
P
T
G
Site 114
T734
A
S
E
A
Q
T
H
T
A
F
P
T
G
D
H
Site 115
S746
G
D
H
K
Q
R
P
S
A
R
N
L
K
G
H
Site 116
S755
R
N
L
K
G
H
R
S
L
S
P
S
S
N
S
Site 117
S757
L
K
G
H
R
S
L
S
P
S
S
N
S
A
F
Site 118
S759
G
H
R
S
L
S
P
S
S
N
S
A
F
S
R
Site 119
S760
H
R
S
L
S
P
S
S
N
S
A
F
S
R
T
Site 120
S762
S
L
S
P
S
S
N
S
A
F
S
R
T
S
L
Site 121
S765
P
S
S
N
S
A
F
S
R
T
S
L
S
V
D
Site 122
S768
N
S
A
F
S
R
T
S
L
S
V
D
Q
A
P
Site 123
S770
A
F
S
R
T
S
L
S
V
D
Q
A
P
T
P
Site 124
T776
L
S
V
D
Q
A
P
T
P
K
A
G
R
S
Q
Site 125
S782
P
T
P
K
A
G
R
S
Q
P
C
V
D
V
H
Site 126
S812
E
P
T
G
P
C
N
S
K
Q
L
F
G
Q
F
Site 127
S825
Q
F
L
L
K
P
V
S
R
R
P
W
D
L
I
Site 128
S833
R
R
P
W
D
L
I
S
Q
L
E
S
F
N
K
Site 129
S837
D
L
I
S
Q
L
E
S
F
N
K
E
L
Q
E
Site 130
S848
E
L
Q
E
E
E
E
S
S
S
S
S
S
S
S
Site 131
S849
L
Q
E
E
E
E
S
S
S
S
S
S
S
S
S
Site 132
S850
Q
E
E
E
E
S
S
S
S
S
S
S
S
S
S
Site 133
S851
E
E
E
E
S
S
S
S
S
S
S
S
S
S
S
Site 134
S852
E
E
E
S
S
S
S
S
S
S
S
S
S
S
S
Site 135
S853
E
E
S
S
S
S
S
S
S
S
S
S
S
S
E
Site 136
S854
E
S
S
S
S
S
S
S
S
S
S
S
S
E
E
Site 137
S855
S
S
S
S
S
S
S
S
S
S
S
S
E
E
S
Site 138
S856
S
S
S
S
S
S
S
S
S
S
S
E
E
S
E
Site 139
S857
S
S
S
S
S
S
S
S
S
S
E
E
S
E
A
Site 140
S858
S
S
S
S
S
S
S
S
S
E
E
S
E
A
E
Site 141
S859
S
S
S
S
S
S
S
S
E
E
S
E
A
E
P
Site 142
S862
S
S
S
S
S
E
E
S
E
A
E
P
Q
Q
E
Site 143
S885
D
V
G
F
R
G
N
S
P
E
M
R
V
E
P
Site 144
S901
P
R
M
W
V
P
E
S
P
V
C
R
S
G
R
Site 145
S906
P
E
S
P
V
C
R
S
G
R
G
E
S
K
S
Site 146
S911
C
R
S
G
R
G
E
S
K
S
E
S
W
S
E
Site 147
S913
S
G
R
G
E
S
K
S
E
S
W
S
E
E
L
Site 148
S915
R
G
E
S
K
S
E
S
W
S
E
E
L
Q
P
Site 149
S917
E
S
K
S
E
S
W
S
E
E
L
Q
P
G
H
Site 150
S931
H
P
R
A
W
P
P
S
P
G
R
F
R
V
E
Site 151
S947
G
G
G
A
P
F
C
S
A
D
G
S
T
S
A
Site 152
S951
P
F
C
S
A
D
G
S
T
S
A
E
K
R
H
Site 153
S962
E
K
R
H
L
E
V
S
N
G
M
D
E
L
A
Site 154
S971
G
M
D
E
L
A
G
S
P
F
P
V
T
R
M
Site 155
T976
A
G
S
P
F
P
V
T
R
M
S
S
R
S
S
Site 156
S979
P
F
P
V
T
R
M
S
S
R
S
S
D
A
K
Site 157
S980
F
P
V
T
R
M
S
S
R
S
S
D
A
K
P
Site 158
S982
V
T
R
M
S
S
R
S
S
D
A
K
P
L
P
Site 159
S983
T
R
M
S
S
R
S
S
D
A
K
P
L
P
A
Site 160
S991
D
A
K
P
L
P
A
S
Y
P
A
E
P
R
E
Site 161
S1002
E
P
R
E
P
Q
E
S
P
K
I
T
S
A
F
Site 162
T1006
P
Q
E
S
P
K
I
T
S
A
F
S
S
V
K
Site 163
S1007
Q
E
S
P
K
I
T
S
A
F
S
S
V
K
P
Site 164
S1010
P
K
I
T
S
A
F
S
S
V
K
P
S
E
A
Site 165
S1011
K
I
T
S
A
F
S
S
V
K
P
S
E
A
V
Site 166
S1015
A
F
S
S
V
K
P
S
E
A
V
P
R
K
F
Site 167
S1024
A
V
P
R
K
F
D
S
G
G
E
R
G
A
G
Site 168
S1035
R
G
A
G
L
P
L
S
L
S
N
K
N
R
G
Site 169
S1037
A
G
L
P
L
S
L
S
N
K
N
R
G
L
S
Site 170
S1044
S
N
K
N
R
G
L
S
A
P
D
L
R
S
V
Site 171
S1050
L
S
A
P
D
L
R
S
V
G
L
T
P
G
Q
Site 172
T1054
D
L
R
S
V
G
L
T
P
G
Q
E
Q
G
A
Site 173
S1062
P
G
Q
E
Q
G
A
S
E
L
E
G
S
L
G
Site 174
S1067
G
A
S
E
L
E
G
S
L
G
E
A
S
T
I
Site 175
S1072
E
G
S
L
G
E
A
S
T
I
E
I
P
P
G
Site 176
T1073
G
S
L
G
E
A
S
T
I
E
I
P
P
G
E
Site 177
S1117
Q
P
A
E
P
D
A
S
A
C
T
P
E
S
P
Site 178
T1120
E
P
D
A
S
A
C
T
P
E
S
P
Q
E
E
Site 179
S1123
A
S
A
C
T
P
E
S
P
Q
E
E
L
L
S
Site 180
S1130
S
P
Q
E
E
L
L
S
R
P
A
P
A
D
V
Site 181
S1141
P
A
D
V
P
R
V
S
T
D
A
F
Y
G
R
Site 182
T1142
A
D
V
P
R
V
S
T
D
A
F
Y
G
R
R
Site 183
Y1146
R
V
S
T
D
A
F
Y
G
R
R
K
C
G
W
Site 184
T1154
G
R
R
K
C
G
W
T
K
S
P
L
F
V
G
Site 185
S1156
R
K
C
G
W
T
K
S
P
L
F
V
G
D
R
Site 186
S1165
L
F
V
G
D
R
D
S
A
R
R
A
P
Q
A
Site 187
S1184
D
V
D
G
V
V
T
S
T
D
P
V
P
E
P
Site 188
S1194
P
V
P
E
P
E
P
S
P
L
E
S
K
F
F
Site 189
S1198
P
E
P
S
P
L
E
S
K
F
F
E
Q
K
D
Site 190
T1208
F
E
Q
K
D
V
E
T
K
P
P
F
R
S
T
Site 191
T1215
T
K
P
P
F
R
S
T
L
F
H
F
V
E
R
Site 192
T1223
L
F
H
F
V
E
R
T
P
S
V
A
G
S
E
Site 193
S1225
H
F
V
E
R
T
P
S
V
A
G
S
E
K
R
Site 194
S1229
R
T
P
S
V
A
G
S
E
K
R
L
R
S
P
Site 195
S1235
G
S
E
K
R
L
R
S
P
S
K
V
I
E
S
Site 196
S1237
E
K
R
L
R
S
P
S
K
V
I
E
S
L
Q
Site 197
S1242
S
P
S
K
V
I
E
S
L
Q
E
K
L
A
S
Site 198
S1249
S
L
Q
E
K
L
A
S
P
P
R
R
A
D
P
Site 199
S1266
L
M
R
M
K
E
V
S
S
V
S
R
M
R
V
Site 200
S1267
M
R
M
K
E
V
S
S
V
S
R
M
R
V
L
Site 201
S1269
M
K
E
V
S
S
V
S
R
M
R
V
L
S
F
Site 202
S1275
V
S
R
M
R
V
L
S
F
R
N
A
D
S
Q
Site 203
S1281
L
S
F
R
N
A
D
S
Q
E
D
A
E
E
L
Site 204
T1291
D
A
E
E
L
K
A
T
T
R
G
Q
A
G
L
Site 205
S1304
G
L
P
G
G
L
V
S
P
G
S
G
D
R
A
Site 206
S1307
G
G
L
V
S
P
G
S
G
D
R
A
Q
R
L
Site 207
S1317
R
A
Q
R
L
G
H
S
L
S
V
S
K
D
S
Site 208
S1319
Q
R
L
G
H
S
L
S
V
S
K
D
S
I
S
Site 209
S1321
L
G
H
S
L
S
V
S
K
D
S
I
S
R
E
Site 210
S1324
S
L
S
V
S
K
D
S
I
S
R
E
E
K
E
Site 211
S1326
S
V
S
K
D
S
I
S
R
E
E
K
E
H
P
Site 212
S1340
P
A
A
Q
K
E
K
S
M
D
Q
D
F
W
C
Site 213
Y1351
D
F
W
C
P
D
S
Y
D
P
S
R
V
E
R
Site 214
S1354
C
P
D
S
Y
D
P
S
R
V
E
R
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation