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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DIP2B
Full Name:
Disco-interacting protein 2 homolog B
Alias:
KIAA1463
Type:
Uncharacterized protein
Mass (Da):
171492
Number AA:
1576
UniProt ID:
Q9P265
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0008134
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
E
R
G
L
E
P
S
P
A
A
V
A
A
L
Site 2
S32
A
E
L
E
L
E
L
S
E
G
D
I
T
Q
K
Site 3
T37
E
L
S
E
G
D
I
T
Q
K
G
Y
E
K
K
Site 4
S46
K
G
Y
E
K
K
R
S
K
L
L
S
P
Y
S
Site 5
S50
K
K
R
S
K
L
L
S
P
Y
S
P
Q
T
Q
Site 6
S53
S
K
L
L
S
P
Y
S
P
Q
T
Q
E
T
D
Site 7
T56
L
S
P
Y
S
P
Q
T
Q
E
T
D
S
A
V
Site 8
T71
Q
K
E
L
R
N
Q
T
P
A
P
S
A
A
Q
Site 9
S75
R
N
Q
T
P
A
P
S
A
A
Q
T
S
A
P
Site 10
T79
P
A
P
S
A
A
Q
T
S
A
P
S
K
Y
H
Site 11
S80
A
P
S
A
A
Q
T
S
A
P
S
K
Y
H
R
Site 12
Y85
Q
T
S
A
P
S
K
Y
H
R
T
R
S
G
G
Site 13
S90
S
K
Y
H
R
T
R
S
G
G
A
R
D
E
R
Site 14
Y98
G
G
A
R
D
E
R
Y
R
S
D
I
H
T
E
Site 15
S100
A
R
D
E
R
Y
R
S
D
I
H
T
E
A
V
Site 16
T104
R
Y
R
S
D
I
H
T
E
A
V
Q
A
A
L
Site 17
T125
K
M
A
L
P
M
P
T
K
R
R
S
T
F
V
Site 18
S129
P
M
P
T
K
R
R
S
T
F
V
Q
S
P
A
Site 19
T130
M
P
T
K
R
R
S
T
F
V
Q
S
P
A
D
Site 20
S134
R
R
S
T
F
V
Q
S
P
A
D
A
C
T
P
Site 21
T140
Q
S
P
A
D
A
C
T
P
P
D
T
S
S
A
Site 22
T144
D
A
C
T
P
P
D
T
S
S
A
S
E
D
E
Site 23
S145
A
C
T
P
P
D
T
S
S
A
S
E
D
E
G
Site 24
S146
C
T
P
P
D
T
S
S
A
S
E
D
E
G
S
Site 25
S148
P
P
D
T
S
S
A
S
E
D
E
G
S
L
R
Site 26
S153
S
A
S
E
D
E
G
S
L
R
R
Q
A
A
L
Site 27
S161
L
R
R
Q
A
A
L
S
A
A
L
Q
Q
S
L
Site 28
S167
L
S
A
A
L
Q
Q
S
L
Q
N
A
E
S
W
Site 29
S173
Q
S
L
Q
N
A
E
S
W
I
N
R
S
I
Q
Site 30
S178
A
E
S
W
I
N
R
S
I
Q
G
S
S
T
S
Site 31
S182
I
N
R
S
I
Q
G
S
S
T
S
S
S
A
S
Site 32
S183
N
R
S
I
Q
G
S
S
T
S
S
S
A
S
S
Site 33
T184
R
S
I
Q
G
S
S
T
S
S
S
A
S
S
T
Site 34
S185
S
I
Q
G
S
S
T
S
S
S
A
S
S
T
L
Site 35
S186
I
Q
G
S
S
T
S
S
S
A
S
S
T
L
S
Site 36
S187
Q
G
S
S
T
S
S
S
A
S
S
T
L
S
H
Site 37
S189
S
S
T
S
S
S
A
S
S
T
L
S
H
G
E
Site 38
S190
S
T
S
S
S
A
S
S
T
L
S
H
G
E
V
Site 39
T191
T
S
S
S
A
S
S
T
L
S
H
G
E
V
K
Site 40
S193
S
S
A
S
S
T
L
S
H
G
E
V
K
G
T
Site 41
T200
S
H
G
E
V
K
G
T
S
G
S
L
A
D
V
Site 42
S203
E
V
K
G
T
S
G
S
L
A
D
V
F
A
N
Site 43
S217
N
T
R
I
E
N
F
S
A
P
P
D
V
T
T
Site 44
T223
F
S
A
P
P
D
V
T
T
T
T
S
S
S
S
Site 45
T224
S
A
P
P
D
V
T
T
T
T
S
S
S
S
S
Site 46
T225
A
P
P
D
V
T
T
T
T
S
S
S
S
S
S
Site 47
T226
P
P
D
V
T
T
T
T
S
S
S
S
S
S
S
Site 48
S227
P
D
V
T
T
T
T
S
S
S
S
S
S
S
S
Site 49
S228
D
V
T
T
T
T
S
S
S
S
S
S
S
S
I
Site 50
S229
V
T
T
T
T
S
S
S
S
S
S
S
S
I
R
Site 51
S230
T
T
T
T
S
S
S
S
S
S
S
S
I
R
P
Site 52
S231
T
T
T
S
S
S
S
S
S
S
S
I
R
P
A
Site 53
S232
T
T
S
S
S
S
S
S
S
S
I
R
P
A
N
Site 54
S233
T
S
S
S
S
S
S
S
S
I
R
P
A
N
I
Site 55
S234
S
S
S
S
S
S
S
S
I
R
P
A
N
I
D
Site 56
S255
V
K
G
M
H
K
G
S
N
R
S
S
L
M
D
Site 57
S259
H
K
G
S
N
R
S
S
L
M
D
T
A
D
G
Site 58
T263
N
R
S
S
L
M
D
T
A
D
G
V
P
V
S
Site 59
S270
T
A
D
G
V
P
V
S
S
R
V
S
T
K
I
Site 60
T275
P
V
S
S
R
V
S
T
K
I
Q
Q
L
L
N
Site 61
T283
K
I
Q
Q
L
L
N
T
L
K
R
P
K
R
P
Site 62
S300
K
E
F
F
V
D
D
S
E
E
I
V
E
V
P
Site 63
T322
K
P
E
G
R
Q
M
T
P
V
K
G
E
P
L
Site 64
T348
S
A
L
Q
R
W
G
T
T
Q
A
K
C
S
C
Site 65
Y367
D
M
T
G
K
P
V
Y
T
L
T
Y
G
K
L
Site 66
T370
G
K
P
V
Y
T
L
T
Y
G
K
L
W
S
R
Site 67
S376
L
T
Y
G
K
L
W
S
R
S
L
K
L
A
Y
Site 68
S378
Y
G
K
L
W
S
R
S
L
K
L
A
Y
T
L
Site 69
T384
R
S
L
K
L
A
Y
T
L
L
N
K
L
G
T
Site 70
T391
T
L
L
N
K
L
G
T
K
N
E
P
V
L
K
Site 71
Y407
G
D
R
V
A
L
V
Y
P
N
N
D
P
V
M
Site 72
T437
V
P
I
E
V
P
L
T
R
K
D
A
G
G
Q
Site 73
T471
C
L
K
G
L
P
K
T
Q
N
G
E
I
V
Q
Site 74
T490
P
R
L
K
W
V
V
T
D
S
K
Y
L
S
K
Site 75
S492
L
K
W
V
V
T
D
S
K
Y
L
S
K
P
P
Site 76
Y494
W
V
V
T
D
S
K
Y
L
S
K
P
P
K
D
Site 77
S496
V
T
D
S
K
Y
L
S
K
P
P
K
D
W
Q
Site 78
S507
K
D
W
Q
P
H
I
S
P
A
G
T
E
P
A
Site 79
T511
P
H
I
S
P
A
G
T
E
P
A
Y
I
E
Y
Site 80
Y515
P
A
G
T
E
P
A
Y
I
E
Y
K
T
S
K
Site 81
S521
A
Y
I
E
Y
K
T
S
K
E
G
S
V
M
G
Site 82
S525
Y
K
T
S
K
E
G
S
V
M
G
V
T
V
S
Site 83
T530
E
G
S
V
M
G
V
T
V
S
R
L
A
M
L
Site 84
S544
L
S
H
C
Q
A
L
S
Q
A
C
N
Y
S
E
Site 85
S629
H
R
D
Q
R
D
V
S
L
S
S
L
R
M
L
Site 86
S646
T
D
G
A
N
P
W
S
V
S
S
C
D
A
F
Site 87
T678
A
T
S
A
E
A
M
T
V
A
I
R
R
P
G
Site 88
T711
Y
G
V
I
R
V
N
T
E
D
K
N
S
A
L
Site 89
S716
V
N
T
E
D
K
N
S
A
L
T
V
Q
D
V
Site 90
T719
E
D
K
N
S
A
L
T
V
Q
D
V
G
H
V
Site 91
T746
G
P
P
Q
L
C
K
T
D
E
I
G
E
I
C
Site 92
S755
E
I
G
E
I
C
V
S
S
R
T
G
G
M
M
Site 93
S756
I
G
E
I
C
V
S
S
R
T
G
G
M
M
Y
Site 94
S784
I
P
V
N
S
A
G
S
P
V
G
D
V
P
F
Site 95
S819
M
D
G
L
L
M
V
S
G
R
R
H
N
A
D
Site 96
T831
N
A
D
D
I
V
A
T
G
L
A
V
E
S
I
Site 97
S837
A
T
G
L
A
V
E
S
I
K
T
V
Y
R
G
Site 98
S870
A
E
Q
R
P
D
A
S
E
E
D
S
F
Q
W
Site 99
S874
P
D
A
S
E
E
D
S
F
Q
W
M
S
R
V
Site 100
T917
G
G
I
H
I
S
Q
T
K
Q
L
F
L
E
G
Site 101
S956
Q
P
G
V
G
P
A
S
V
M
V
G
N
L
V
Site 102
T1002
L
Q
W
R
A
Q
A
T
P
D
H
V
L
F
M
Site 103
S1035
K
R
A
E
R
I
A
S
V
L
G
D
K
G
H
Site 104
Y1145
R
K
R
L
P
Q
L
Y
K
P
P
T
P
E
M
Site 105
T1149
P
Q
L
Y
K
P
P
T
P
E
M
L
A
Y
L
Site 106
Y1155
P
T
P
E
M
L
A
Y
L
D
F
S
V
S
T
Site 107
S1221
S
V
Y
S
G
H
Q
S
V
L
I
P
P
M
E
Site 108
T1271
N
Q
V
E
V
L
K
T
R
G
I
N
L
S
C
Site 109
S1297
P
R
V
A
L
Q
Q
S
F
S
K
L
F
K
D
Site 110
S1313
G
L
S
P
R
A
V
S
T
T
F
G
S
R
V
Site 111
T1314
L
S
P
R
A
V
S
T
T
F
G
S
R
V
N
Site 112
T1315
S
P
R
A
V
S
T
T
F
G
S
R
V
N
V
Site 113
T1336
T
S
G
P
D
P
T
T
V
Y
V
D
L
K
S
Site 114
Y1338
G
P
D
P
T
T
V
Y
V
D
L
K
S
L
R
Site 115
S1343
T
V
Y
V
D
L
K
S
L
R
H
D
R
V
R
Site 116
S1359
V
E
R
G
A
P
Q
S
L
L
L
S
E
S
G
Site 117
S1365
Q
S
L
L
L
S
E
S
G
K
I
L
P
G
V
Site 118
S1388
T
K
G
P
V
G
D
S
H
L
G
E
I
W
V
Site 119
S1397
L
G
E
I
W
V
N
S
P
H
T
A
S
G
Y
Site 120
Y1404
S
P
H
T
A
S
G
Y
Y
T
I
Y
D
S
E
Site 121
T1406
H
T
A
S
G
Y
Y
T
I
Y
D
S
E
T
L
Site 122
Y1408
A
S
G
Y
Y
T
I
Y
D
S
E
T
L
Q
A
Site 123
S1423
D
H
F
N
T
R
L
S
F
G
D
A
A
Q
T
Site 124
T1430
S
F
G
D
A
A
Q
T
L
W
A
R
T
G
Y
Site 125
Y1437
T
L
W
A
R
T
G
Y
L
G
F
V
R
R
T
Site 126
T1447
F
V
R
R
T
E
L
T
A
A
T
G
E
R
H
Site 127
Y1458
G
E
R
H
D
A
L
Y
V
V
G
A
L
D
E
Site 128
T1481
Y
H
P
I
D
I
E
T
S
V
S
R
I
H
R
Site 129
S1482
H
P
I
D
I
E
T
S
V
S
R
I
H
R
S
Site 130
S1484
I
D
I
E
T
S
V
S
R
I
H
R
S
I
A
Site 131
S1561
Q
R
M
H
L
R
D
S
F
L
A
D
Q
L
D
Site 132
Y1571
A
D
Q
L
D
P
I
Y
V
A
Y
N
M
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation