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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1468
Full Name:
LisH domain and HEAT repeat-containing protein KIAA1468
Alias:
FLJ33841; HsT3308; HsT885; K1468; KIAAKIAA1468, isoform CRA_a; NP_065905
Type:
Uncharacterized protein
Mass (Da):
134630
Number AA:
1216
UniProt ID:
Q9P260
International Prot ID:
IPI00797368
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
M
A
P
G
G
S
G
S
G
G
G
V
N
P
F
Site 2
S20
G
G
V
N
P
F
L
S
D
S
D
E
D
D
D
Site 3
S22
V
N
P
F
L
S
D
S
D
E
D
D
D
E
V
Site 4
T32
D
D
D
E
V
A
A
T
E
E
R
R
A
V
L
Site 5
S51
G
S
G
L
D
P
G
S
A
G
S
L
S
P
Q
Site 6
S54
L
D
P
G
S
A
G
S
L
S
P
Q
D
P
V
Site 7
S56
P
G
S
A
G
S
L
S
P
Q
D
P
V
A
L
Site 8
S65
Q
D
P
V
A
L
G
S
S
A
R
P
G
L
P
Site 9
S66
D
P
V
A
L
G
S
S
A
R
P
G
L
P
G
Site 10
T88
A
L
G
G
T
G
E
T
P
A
R
L
S
I
D
Site 11
S120
L
H
T
E
L
L
E
S
G
R
E
L
P
R
L
Site 12
Y130
E
L
P
R
L
R
D
Y
F
S
N
P
G
N
F
Site 13
S132
P
R
L
R
D
Y
F
S
N
P
G
N
F
E
R
Site 14
S141
P
G
N
F
E
R
Q
S
G
T
P
P
G
M
G
Site 15
T143
N
F
E
R
Q
S
G
T
P
P
G
M
G
A
P
Site 16
S167
G
A
G
G
R
E
P
S
T
A
S
G
G
G
Q
Site 17
T168
A
G
G
R
E
P
S
T
A
S
G
G
G
Q
L
Site 18
S170
G
R
E
P
S
T
A
S
G
G
G
Q
L
N
R
Site 19
S180
G
Q
L
N
R
A
G
S
I
S
T
L
D
S
L
Site 20
S182
L
N
R
A
G
S
I
S
T
L
D
S
L
D
F
Site 21
T183
N
R
A
G
S
I
S
T
L
D
S
L
D
F
A
Site 22
S186
G
S
I
S
T
L
D
S
L
D
F
A
R
Y
S
Site 23
Y192
D
S
L
D
F
A
R
Y
S
D
D
G
N
R
E
Site 24
S193
S
L
D
F
A
R
Y
S
D
D
G
N
R
E
T
Site 25
T200
S
D
D
G
N
R
E
T
D
E
K
V
A
V
L
Site 26
Y241
P
L
Q
E
R
K
N
Y
K
S
S
P
E
I
Q
Site 27
S243
Q
E
R
K
N
Y
K
S
S
P
E
I
Q
E
P
Site 28
S244
E
R
K
N
Y
K
S
S
P
E
I
Q
E
P
I
Site 29
Y272
E
F
L
L
K
N
N
Y
K
L
T
S
I
T
F
Site 30
S276
K
N
N
Y
K
L
T
S
I
T
F
S
D
E
N
Site 31
T278
N
Y
K
L
T
S
I
T
F
S
D
E
N
D
D
Site 32
S280
K
L
T
S
I
T
F
S
D
E
N
D
D
Q
D
Site 33
Y308
P
P
D
L
L
Q
L
Y
R
D
F
G
N
H
Q
Site 34
S326
K
D
L
V
D
V
A
S
G
V
E
E
D
E
L
Site 35
T337
E
D
E
L
E
A
L
T
P
I
I
S
N
L
P
Site 36
T346
I
I
S
N
L
P
P
T
L
E
T
P
Q
P
A
Site 37
T349
N
L
P
P
T
L
E
T
P
Q
P
A
E
N
S
Site 38
S367
Q
K
L
E
D
K
I
S
L
L
N
S
E
K
W
Site 39
S371
D
K
I
S
L
L
N
S
E
K
W
S
L
M
E
Site 40
S375
L
L
N
S
E
K
W
S
L
M
E
Q
I
R
R
Site 41
S385
E
Q
I
R
R
L
K
S
E
M
D
F
L
K
N
Site 42
S416
D
Q
L
P
H
K
D
S
E
D
S
G
Q
H
P
Site 43
S428
Q
H
P
D
V
N
S
S
D
K
G
K
N
T
D
Site 44
T434
S
S
D
K
G
K
N
T
D
I
H
L
S
I
S
Site 45
S439
K
N
T
D
I
H
L
S
I
S
D
E
A
D
S
Site 46
S441
T
D
I
H
L
S
I
S
D
E
A
D
S
T
I
Site 47
S446
S
I
S
D
E
A
D
S
T
I
P
K
E
N
S
Site 48
T447
I
S
D
E
A
D
S
T
I
P
K
E
N
S
P
Site 49
S453
S
T
I
P
K
E
N
S
P
N
S
F
P
R
R
Site 50
S456
P
K
E
N
S
P
N
S
F
P
R
R
E
R
E
Site 51
S468
E
R
E
G
M
P
P
S
S
L
S
S
K
K
T
Site 52
S469
R
E
G
M
P
P
S
S
L
S
S
K
K
T
V
Site 53
S471
G
M
P
P
S
S
L
S
S
K
K
T
V
H
F
Site 54
S472
M
P
P
S
S
L
S
S
K
K
T
V
H
F
D
Site 55
T475
S
S
L
S
S
K
K
T
V
H
F
D
K
P
N
Site 56
S486
D
K
P
N
R
K
L
S
P
A
F
H
Q
A
L
Site 57
S503
F
C
R
M
S
A
D
S
R
L
G
Y
E
V
S
Site 58
Y507
S
A
D
S
R
L
G
Y
E
V
S
R
I
A
D
Site 59
S510
S
R
L
G
Y
E
V
S
R
I
A
D
S
E
K
Site 60
S515
E
V
S
R
I
A
D
S
E
K
S
V
M
L
M
Site 61
S518
R
I
A
D
S
E
K
S
V
M
L
M
L
G
R
Site 62
T549
L
I
P
L
I
L
C
T
A
C
L
H
P
E
P
Site 63
Y613
W
E
Q
I
N
H
K
Y
P
E
R
R
L
L
V
Site 64
Y630
S
C
G
A
L
A
P
Y
L
P
K
E
I
R
S
Site 65
Y670
S
L
G
I
I
M
G
Y
I
D
D
P
D
K
Y
Site 66
Y677
Y
I
D
D
P
D
K
Y
H
Q
G
F
E
L
L
Site 67
S686
Q
G
F
E
L
L
L
S
A
L
G
D
P
S
E
Site 68
S697
D
P
S
E
R
V
V
S
A
T
H
Q
V
F
L
Site 69
Y748
D
E
H
K
L
H
M
Y
L
S
A
L
Q
S
L
Site 70
S770
V
L
Q
N
A
P
F
S
S
K
A
K
L
H
G
Site 71
T785
E
V
P
Q
I
E
V
T
R
F
P
R
P
M
S
Site 72
S792
T
R
F
P
R
P
M
S
P
L
Q
D
V
S
T
Site 73
S798
M
S
P
L
Q
D
V
S
T
I
I
G
S
R
E
Site 74
T799
S
P
L
Q
D
V
S
T
I
I
G
S
R
E
Q
Site 75
Y816
V
L
L
Q
L
Y
D
Y
Q
L
E
Q
E
G
T
Site 76
T823
Y
Q
L
E
Q
E
G
T
T
G
W
E
S
L
L
Site 77
S889
F
Q
E
I
L
R
L
S
E
E
N
I
D
S
S
Site 78
S895
L
S
E
E
N
I
D
S
S
A
G
N
G
V
L
Site 79
S896
S
E
E
N
I
D
S
S
A
G
N
G
V
L
T
Site 80
Y918
A
T
G
V
L
T
C
Y
I
Q
E
E
D
R
K
Site 81
T991
A
A
R
M
F
E
L
T
L
R
G
M
S
E
A
Site 82
S996
E
L
T
L
R
G
M
S
E
A
L
V
D
K
R
Site 83
S1013
P
A
L
V
T
L
S
S
D
P
E
F
S
V
R
Site 84
S1049
R
V
K
M
Q
L
A
S
F
L
E
D
P
Q
Y
Site 85
Y1056
S
F
L
E
D
P
Q
Y
Q
D
Q
H
S
L
H
Site 86
S1061
P
Q
Y
Q
D
Q
H
S
L
H
T
E
I
I
K
Site 87
T1069
L
H
T
E
I
I
K
T
F
G
R
V
G
P
N
Site 88
S1104
N
N
L
Q
I
V
D
S
K
R
L
D
I
A
T
Site 89
T1111
S
K
R
L
D
I
A
T
H
L
F
E
A
Y
S
Site 90
T1143
P
G
L
R
C
L
R
T
D
M
E
H
L
S
P
Site 91
S1149
R
T
D
M
E
H
L
S
P
E
H
E
V
I
L
Site 92
S1157
P
E
H
E
V
I
L
S
S
M
I
K
E
C
E
Site 93
S1158
E
H
E
V
I
L
S
S
M
I
K
E
C
E
Q
Site 94
S1178
T
V
Q
E
P
Q
G
S
M
S
I
A
A
S
L
Site 95
S1180
Q
E
P
Q
G
S
M
S
I
A
A
S
L
V
S
Site 96
S1184
G
S
M
S
I
A
A
S
L
V
S
E
D
T
K
Site 97
T1190
A
S
L
V
S
E
D
T
K
T
K
F
L
N
K
Site 98
T1192
L
V
S
E
D
T
K
T
K
F
L
N
K
M
G
Site 99
T1202
L
N
K
M
G
Q
L
T
T
S
G
A
M
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation