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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRFN1
Full Name:
Leucine-rich repeat and fibronectin type III domain-containing protein 1
Alias:
KIAA1484; Leucine rich repeat and fibronectin type III domain containing 1; SALM2; Synaptic adhesion-like molecule 2
Type:
Membrane, Synapse, Cell junction, Integral membrane protein
Mass (Da):
82318
Number AA:
771
UniProt ID:
Q9P244
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0016021
GO:0045202
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004871
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0006944
GO:0043123
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S97
S
L
V
H
L
T
L
S
R
N
T
I
G
Q
V
Site 2
Y454
P
V
P
G
I
R
M
Y
Q
V
Q
Y
N
S
S
Site 3
Y458
I
R
M
Y
Q
V
Q
Y
N
S
S
V
D
D
S
Site 4
S475
Y
R
M
I
P
S
T
S
Q
T
F
L
V
N
D
Site 5
T477
M
I
P
S
T
S
Q
T
F
L
V
N
D
L
A
Site 6
S567
K
V
Y
G
D
G
D
S
R
R
V
K
G
S
R
Site 7
S573
D
S
R
R
V
K
G
S
R
S
L
P
R
V
S
Site 8
S575
R
R
V
K
G
S
R
S
L
P
R
V
S
H
V
Site 9
S580
S
R
S
L
P
R
V
S
H
V
C
S
Q
T
N
Site 10
S584
P
R
V
S
H
V
C
S
Q
T
N
G
A
G
T
Site 11
Y605
A
L
P
A
Q
D
H
Y
E
A
L
R
E
V
E
Site 12
S613
E
A
L
R
E
V
E
S
Q
A
A
P
A
V
A
Site 13
S646
L
G
R
S
L
G
G
S
A
T
S
L
C
L
L
Site 14
S655
T
S
L
C
L
L
P
S
E
E
T
S
G
E
E
Site 15
S659
L
L
P
S
E
E
T
S
G
E
E
S
R
A
A
Site 16
S663
E
E
T
S
G
E
E
S
R
A
A
V
G
P
R
Site 17
S672
A
A
V
G
P
R
R
S
R
S
G
A
L
E
P
Site 18
S674
V
G
P
R
R
S
R
S
G
A
L
E
P
P
T
Site 19
T681
S
G
A
L
E
P
P
T
S
A
P
P
T
L
A
Site 20
Y704
R
P
R
P
Q
Q
R
Y
S
F
D
G
D
Y
G
Site 21
S705
P
R
P
Q
Q
R
Y
S
F
D
G
D
Y
G
A
Site 22
Y710
R
Y
S
F
D
G
D
Y
G
A
L
F
Q
S
H
Site 23
S716
D
Y
G
A
L
F
Q
S
H
S
Y
P
R
R
A
Site 24
S718
G
A
L
F
Q
S
H
S
Y
P
R
R
A
R
R
Site 25
Y719
A
L
F
Q
S
H
S
Y
P
R
R
A
R
R
T
Site 26
T726
Y
P
R
R
A
R
R
T
K
R
H
R
S
T
P
Site 27
S731
R
R
T
K
R
H
R
S
T
P
H
L
D
G
A
Site 28
T732
R
T
K
R
H
R
S
T
P
H
L
D
G
A
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation