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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1486
Full Name:
Uncharacterized protein KIAA1486
Alias:
kiaa1486; loc57624
Type:
Unknown function
Mass (Da):
70544
Number AA:
653
UniProt ID:
Q9P242
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
I
S
S
K
M
M
S
S
N
P
E
E
D
P
Site 2
S9
I
S
S
K
M
M
S
S
N
P
E
E
D
P
L
Site 3
T18
P
E
E
D
P
L
D
T
F
L
Q
Y
I
E
D
Site 4
Y22
P
L
D
T
F
L
Q
Y
I
E
D
M
G
M
K
Site 5
S40
G
L
V
I
Q
N
A
S
D
I
A
R
E
N
D
Site 6
T53
N
D
R
L
R
N
E
T
N
L
A
Y
L
K
E
Site 7
S86
V
G
R
G
H
E
G
S
Y
V
G
K
H
F
R
Site 8
Y87
G
R
G
H
E
G
S
Y
V
G
K
H
F
R
M
Site 9
S111
D
R
L
P
H
P
C
S
S
G
F
S
V
R
S
Site 10
S112
R
L
P
H
P
C
S
S
G
F
S
V
R
S
Q
Site 11
S115
H
P
C
S
S
G
F
S
V
R
S
Q
S
L
H
Site 12
S118
S
S
G
F
S
V
R
S
Q
S
L
H
S
V
G
Site 13
S120
G
F
S
V
R
S
Q
S
L
H
S
V
G
G
T
Site 14
S123
V
R
S
Q
S
L
H
S
V
G
G
T
D
D
D
Site 15
T127
S
L
H
S
V
G
G
T
D
D
D
S
S
C
G
Site 16
S131
V
G
G
T
D
D
D
S
S
C
G
S
R
R
Q
Site 17
S132
G
G
T
D
D
D
S
S
C
G
S
R
R
Q
P
Site 18
S135
D
D
D
S
S
C
G
S
R
R
Q
P
P
P
K
Site 19
S148
P
K
P
K
R
D
P
S
T
K
L
S
T
S
S
Site 20
T149
K
P
K
R
D
P
S
T
K
L
S
T
S
S
E
Site 21
S152
R
D
P
S
T
K
L
S
T
S
S
E
T
V
S
Site 22
S154
P
S
T
K
L
S
T
S
S
E
T
V
S
S
T
Site 23
S155
S
T
K
L
S
T
S
S
E
T
V
S
S
T
A
Site 24
T157
K
L
S
T
S
S
E
T
V
S
S
T
A
A
S
Site 25
S159
S
T
S
S
E
T
V
S
S
T
A
A
S
K
S
Site 26
S160
T
S
S
E
T
V
S
S
T
A
A
S
K
S
G
Site 27
T161
S
S
E
T
V
S
S
T
A
A
S
K
S
G
K
Site 28
S164
T
V
S
S
T
A
A
S
K
S
G
K
T
P
E
Site 29
S166
S
S
T
A
A
S
K
S
G
K
T
P
E
R
T
Site 30
T169
A
A
S
K
S
G
K
T
P
E
R
T
E
A
S
Site 31
S176
T
P
E
R
T
E
A
S
A
K
P
R
P
H
S
Site 32
S183
S
A
K
P
R
P
H
S
D
E
Y
S
K
K
I
Site 33
Y186
P
R
P
H
S
D
E
Y
S
K
K
I
P
P
P
Site 34
S187
R
P
H
S
D
E
Y
S
K
K
I
P
P
P
K
Site 35
T201
K
P
K
R
N
P
N
T
Q
L
S
T
S
F
D
Site 36
S204
R
N
P
N
T
Q
L
S
T
S
F
D
E
T
Y
Site 37
T205
N
P
N
T
Q
L
S
T
S
F
D
E
T
Y
I
Site 38
S206
P
N
T
Q
L
S
T
S
F
D
E
T
Y
I
K
Site 39
T210
L
S
T
S
F
D
E
T
Y
I
K
K
H
G
P
Site 40
Y211
S
T
S
F
D
E
T
Y
I
K
K
H
G
P
R
Site 41
T220
K
K
H
G
P
R
R
T
S
L
P
R
D
S
S
Site 42
S221
K
H
G
P
R
R
T
S
L
P
R
D
S
S
L
Site 43
S226
R
T
S
L
P
R
D
S
S
L
S
Q
M
G
S
Site 44
S227
T
S
L
P
R
D
S
S
L
S
Q
M
G
S
P
Site 45
S229
L
P
R
D
S
S
L
S
Q
M
G
S
P
A
G
Site 46
S233
S
S
L
S
Q
M
G
S
P
A
G
D
P
E
E
Site 47
Y245
P
E
E
E
E
P
V
Y
I
E
M
V
G
N
I
Site 48
S264
R
K
E
D
D
D
Q
S
E
A
V
Y
E
E
M
Site 49
Y268
D
D
Q
S
E
A
V
Y
E
E
M
K
Y
P
I
Site 50
Y273
A
V
Y
E
E
M
K
Y
P
I
F
D
D
L
G
Site 51
T298
S
C
S
S
Q
C
A
T
P
T
V
P
D
L
D
Site 52
T300
S
S
Q
C
A
T
P
T
V
P
D
L
D
F
A
Site 53
S310
D
L
D
F
A
K
A
S
V
P
C
P
P
K
G
Site 54
S347
P
P
A
P
V
H
C
S
P
N
S
D
E
S
P
Site 55
S350
P
V
H
C
S
P
N
S
D
E
S
P
L
T
P
Site 56
S353
C
S
P
N
S
D
E
S
P
L
T
P
L
E
V
Site 57
T356
N
S
D
E
S
P
L
T
P
L
E
V
T
K
L
Site 58
Y371
P
V
L
E
N
V
S
Y
M
K
Q
P
A
G
A
Site 59
S379
M
K
Q
P
A
G
A
S
P
S
T
L
P
S
H
Site 60
S381
Q
P
A
G
A
S
P
S
T
L
P
S
H
V
P
Site 61
T382
P
A
G
A
S
P
S
T
L
P
S
H
V
P
G
Site 62
S385
A
S
P
S
T
L
P
S
H
V
P
G
H
A
K
Site 63
S411
A
S
A
T
P
A
L
S
S
S
P
P
P
P
S
Site 64
S412
S
A
T
P
A
L
S
S
S
P
P
P
P
S
T
Site 65
S413
A
T
P
A
L
S
S
S
P
P
P
P
S
T
L
Site 66
S418
S
S
S
P
P
P
P
S
T
L
Y
R
T
Q
S
Site 67
T419
S
S
P
P
P
P
S
T
L
Y
R
T
Q
S
P
Site 68
Y421
P
P
P
P
S
T
L
Y
R
T
Q
S
P
H
G
Site 69
T423
P
P
S
T
L
Y
R
T
Q
S
P
H
G
Y
P
Site 70
S425
S
T
L
Y
R
T
Q
S
P
H
G
Y
P
K
S
Site 71
Y429
R
T
Q
S
P
H
G
Y
P
K
S
H
S
T
S
Site 72
S432
S
P
H
G
Y
P
K
S
H
S
T
S
P
S
P
Site 73
S434
H
G
Y
P
K
S
H
S
T
S
P
S
P
V
S
Site 74
S436
Y
P
K
S
H
S
T
S
P
S
P
V
S
M
G
Site 75
S438
K
S
H
S
T
S
P
S
P
V
S
M
G
R
S
Site 76
S441
S
T
S
P
S
P
V
S
M
G
R
S
L
T
P
Site 77
S445
S
P
V
S
M
G
R
S
L
T
P
L
S
L
K
Site 78
T447
V
S
M
G
R
S
L
T
P
L
S
L
K
R
P
Site 79
S450
G
R
S
L
T
P
L
S
L
K
R
P
P
P
Y
Site 80
Y457
S
L
K
R
P
P
P
Y
D
A
V
H
S
G
S
Site 81
S462
P
P
Y
D
A
V
H
S
G
S
L
S
R
S
S
Site 82
S464
Y
D
A
V
H
S
G
S
L
S
R
S
S
P
S
Site 83
S466
A
V
H
S
G
S
L
S
R
S
S
P
S
V
P
Site 84
S468
H
S
G
S
L
S
R
S
S
P
S
V
P
H
S
Site 85
S469
S
G
S
L
S
R
S
S
P
S
V
P
H
S
T
Site 86
S471
S
L
S
R
S
S
P
S
V
P
H
S
T
P
R
Site 87
S475
S
S
P
S
V
P
H
S
T
P
R
P
V
S
Q
Site 88
T476
S
P
S
V
P
H
S
T
P
R
P
V
S
Q
D
Site 89
S481
H
S
T
P
R
P
V
S
Q
D
G
A
K
M
V
Site 90
T494
M
V
N
A
A
V
N
T
Y
G
A
A
P
G
G
Site 91
Y495
V
N
A
A
V
N
T
Y
G
A
A
P
G
G
S
Site 92
S502
Y
G
A
A
P
G
G
S
R
S
R
T
P
T
S
Site 93
S504
A
A
P
G
G
S
R
S
R
T
P
T
S
P
L
Site 94
T506
P
G
G
S
R
S
R
T
P
T
S
P
L
E
E
Site 95
T508
G
S
R
S
R
T
P
T
S
P
L
E
E
L
T
Site 96
S509
S
R
S
R
T
P
T
S
P
L
E
E
L
T
S
Site 97
T515
T
S
P
L
E
E
L
T
S
L
F
S
S
G
R
Site 98
S516
S
P
L
E
E
L
T
S
L
F
S
S
G
R
S
Site 99
S519
E
E
L
T
S
L
F
S
S
G
R
S
L
L
R
Site 100
S520
E
L
T
S
L
F
S
S
G
R
S
L
L
R
K
Site 101
S523
S
L
F
S
S
G
R
S
L
L
R
K
S
S
S
Site 102
S528
G
R
S
L
L
R
K
S
S
S
G
R
R
S
K
Site 103
S529
R
S
L
L
R
K
S
S
S
G
R
R
S
K
E
Site 104
S530
S
L
L
R
K
S
S
S
G
R
R
S
K
E
P
Site 105
S534
K
S
S
S
G
R
R
S
K
E
P
A
E
K
S
Site 106
S541
S
K
E
P
A
E
K
S
T
E
E
L
K
V
R
Site 107
S551
E
L
K
V
R
S
H
S
T
E
P
L
P
K
L
Site 108
S569
E
R
G
H
H
G
A
S
S
S
R
E
P
V
K
Site 109
S570
R
G
H
H
G
A
S
S
S
R
E
P
V
K
A
Site 110
S571
G
H
H
G
A
S
S
S
R
E
P
V
K
A
Q
Site 111
T583
K
A
Q
E
W
D
G
T
P
G
P
P
V
V
T
Site 112
S591
P
G
P
P
V
V
T
S
R
L
G
R
C
S
V
Site 113
T601
G
R
C
S
V
S
P
T
L
L
A
G
N
H
S
Site 114
S608
T
L
L
A
G
N
H
S
S
E
P
K
V
S
C
Site 115
S609
L
L
A
G
N
H
S
S
E
P
K
V
S
C
K
Site 116
S614
H
S
S
E
P
K
V
S
C
K
L
G
R
S
A
Site 117
S620
V
S
C
K
L
G
R
S
A
S
T
S
G
V
P
Site 118
S622
C
K
L
G
R
S
A
S
T
S
G
V
P
P
P
Site 119
S624
L
G
R
S
A
S
T
S
G
V
P
P
P
S
V
Site 120
S630
T
S
G
V
P
P
P
S
V
T
P
L
R
Q
S
Site 121
T632
G
V
P
P
P
S
V
T
P
L
R
Q
S
S
D
Site 122
S637
S
V
T
P
L
R
Q
S
S
D
L
Q
Q
S
Q
Site 123
S638
V
T
P
L
R
Q
S
S
D
L
Q
Q
S
Q
V
Site 124
S643
Q
S
S
D
L
Q
Q
S
Q
V
P
S
S
L
A
Site 125
S647
L
Q
Q
S
Q
V
P
S
S
L
A
N
R
D
_
Site 126
S648
Q
Q
S
Q
V
P
S
S
L
A
N
R
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation