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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BTBD7
Full Name:
BTB/POZ domain-containing protein 7
Alias:
BTB (POZ) domain containing 7; FLJ10648; FUP1
Type:
Mass (Da):
126350
Number AA:
1132
UniProt ID:
Q9P203
International Prot ID:
IPI00002061
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
G
A
N
A
S
N
Y
P
H
S
C
S
P
R
Site 2
S11
N
A
S
N
Y
P
H
S
C
S
P
R
V
G
G
Site 3
S13
S
N
Y
P
H
S
C
S
P
R
V
G
G
N
S
Site 4
S20
S
P
R
V
G
G
N
S
Q
A
Q
Q
T
F
I
Site 5
T25
G
N
S
Q
A
Q
Q
T
F
I
G
T
S
S
Y
Site 6
S31
Q
T
F
I
G
T
S
S
Y
S
Q
Q
G
Y
G
Site 7
Y32
T
F
I
G
T
S
S
Y
S
Q
Q
G
Y
G
C
Site 8
S33
F
I
G
T
S
S
Y
S
Q
Q
G
Y
G
C
E
Site 9
Y37
S
S
Y
S
Q
Q
G
Y
G
C
E
S
K
L
Y
Site 10
Y44
Y
G
C
E
S
K
L
Y
S
L
D
H
G
H
E
Site 11
S45
G
C
E
S
K
L
Y
S
L
D
H
G
H
E
K
Site 12
T60
P
Q
D
K
K
K
R
T
S
G
L
A
T
L
K
Site 13
S61
Q
D
K
K
K
R
T
S
G
L
A
T
L
K
K
Site 14
T65
K
R
T
S
G
L
A
T
L
K
K
K
F
I
K
Site 15
S76
K
F
I
K
R
R
K
S
N
R
S
A
D
H
A
Site 16
S79
K
R
R
K
S
N
R
S
A
D
H
A
K
Q
M
Site 17
S115
T
S
A
L
K
E
L
S
L
Q
A
S
L
A
R
Site 18
S119
K
E
L
S
L
Q
A
S
L
A
R
P
E
A
R
Site 19
T127
L
A
R
P
E
A
R
T
L
Q
K
D
M
A
D
Site 20
Y136
Q
K
D
M
A
D
L
Y
E
Y
K
Y
C
T
D
Site 21
Y140
A
D
L
Y
E
Y
K
Y
C
T
D
V
D
L
I
Site 22
T169
A
R
C
P
F
F
K
T
L
L
S
S
S
P
E
Site 23
S172
P
F
F
K
T
L
L
S
S
S
P
E
Y
G
A
Site 24
S174
F
K
T
L
L
S
S
S
P
E
Y
G
A
E
I
Site 25
S212
G
E
F
G
M
E
D
S
R
F
Q
N
V
D
I
Site 26
T229
Q
L
S
E
E
F
G
T
P
N
S
L
D
V
D
Site 27
S232
E
E
F
G
T
P
N
S
L
D
V
D
M
R
G
Site 28
S282
K
A
H
K
A
V
I
S
A
R
S
P
F
F
R
Site 29
T298
L
L
Q
R
R
I
R
T
G
E
E
I
T
D
R
Site 30
T306
G
E
E
I
T
D
R
T
L
R
T
P
T
R
I
Site 31
T309
I
T
D
R
T
L
R
T
P
T
R
I
I
L
D
Site 32
T311
D
R
T
L
R
T
P
T
R
I
I
L
D
E
S
Site 33
S318
T
R
I
I
L
D
E
S
I
I
P
K
K
Y
A
Site 34
Y413
L
K
W
S
S
H
P
Y
G
S
K
W
V
H
R
Site 35
T435
E
E
F
S
Q
V
M
T
S
D
V
F
Y
E
L
Site 36
S436
E
F
S
Q
V
M
T
S
D
V
F
Y
E
L
S
Site 37
Y440
V
M
T
S
D
V
F
Y
E
L
S
K
D
H
L
Site 38
T449
L
S
K
D
H
L
L
T
A
I
Q
S
D
Y
L
Site 39
Y455
L
T
A
I
Q
S
D
Y
L
Q
A
S
E
Q
D
Site 40
S459
Q
S
D
Y
L
Q
A
S
E
Q
D
I
L
K
Y
Site 41
Y466
S
E
Q
D
I
L
K
Y
L
I
K
W
G
E
H
Site 42
S488
D
R
E
P
N
L
L
S
G
T
A
H
S
V
N
Site 43
S493
L
L
S
G
T
A
H
S
V
N
K
R
G
V
K
Site 44
S534
P
I
N
S
E
V
L
S
D
A
M
K
R
G
L
Site 45
S543
A
M
K
R
G
L
I
S
T
P
P
S
D
M
L
Site 46
T544
M
K
R
G
L
I
S
T
P
P
S
D
M
L
P
Site 47
S547
G
L
I
S
T
P
P
S
D
M
L
P
T
T
E
Site 48
T553
P
S
D
M
L
P
T
T
E
G
G
K
S
N
A
Site 49
S558
P
T
T
E
G
G
K
S
N
A
W
L
R
Q
K
Site 50
Y570
R
Q
K
N
A
G
I
Y
V
R
P
R
L
F
S
Site 51
S577
Y
V
R
P
R
L
F
S
P
Y
V
E
E
A
K
Site 52
Y579
R
P
R
L
F
S
P
Y
V
E
E
A
K
S
V
Site 53
S585
P
Y
V
E
E
A
K
S
V
L
D
E
M
M
V
Site 54
S606
R
L
R
M
V
R
M
S
N
V
P
D
T
L
Y
Site 55
T611
R
M
S
N
V
P
D
T
L
Y
M
V
N
N
A
Site 56
Y613
S
N
V
P
D
T
L
Y
M
V
N
N
A
V
P
Site 57
S632
M
I
S
H
Q
Q
I
S
S
N
Q
S
S
P
P
Site 58
S633
I
S
H
Q
Q
I
S
S
N
Q
S
S
P
P
S
Site 59
S636
Q
Q
I
S
S
N
Q
S
S
P
P
S
V
V
A
Site 60
S637
Q
I
S
S
N
Q
S
S
P
P
S
V
V
A
N
Site 61
S640
S
N
Q
S
S
P
P
S
V
V
A
N
E
I
P
Site 62
T667
R
L
Q
E
L
R
H
T
E
Q
V
Q
R
A
Y
Site 63
Y674
T
E
Q
V
Q
R
A
Y
A
L
N
C
G
E
G
Site 64
S722
D
E
R
F
G
D
E
S
P
L
L
T
M
R
Q
Site 65
T726
G
D
E
S
P
L
L
T
M
R
Q
P
G
R
C
Site 66
S737
P
G
R
C
R
V
N
S
T
P
P
A
E
T
M
Site 67
T738
G
R
C
R
V
N
S
T
P
P
A
E
T
M
F
Site 68
Y765
L
P
P
P
P
P
P
Y
H
P
P
A
T
P
I
Site 69
T770
P
P
Y
H
P
P
A
T
P
I
H
N
Q
L
K
Site 70
S786
G
W
K
Q
R
P
P
S
Q
H
P
S
R
S
F
Site 71
S790
R
P
P
S
Q
H
P
S
R
S
F
S
Y
P
C
Site 72
S792
P
S
Q
H
P
S
R
S
F
S
Y
P
C
N
H
Site 73
S794
Q
H
P
S
R
S
F
S
Y
P
C
N
H
S
L
Site 74
Y795
H
P
S
R
S
F
S
Y
P
C
N
H
S
L
F
Site 75
S804
C
N
H
S
L
F
H
S
R
T
A
P
K
A
G
Site 76
T806
H
S
L
F
H
S
R
T
A
P
K
A
G
P
P
Site 77
Y816
K
A
G
P
P
P
V
Y
L
P
S
V
K
A
A
Site 78
S819
P
P
P
V
Y
L
P
S
V
K
A
A
P
P
D
Site 79
T828
K
A
A
P
P
D
C
T
S
T
A
G
L
G
R
Site 80
S829
A
A
P
P
D
C
T
S
T
A
G
L
G
R
Q
Site 81
S882
A
V
G
V
S
T
L
S
L
K
D
R
R
L
P
Site 82
T895
L
P
E
L
A
V
D
T
E
L
S
Q
S
V
S
Site 83
S898
L
A
V
D
T
E
L
S
Q
S
V
S
E
A
G
Site 84
S900
V
D
T
E
L
S
Q
S
V
S
E
A
G
P
G
Site 85
S902
T
E
L
S
Q
S
V
S
E
A
G
P
G
P
P
Site 86
S913
P
G
P
P
Q
H
L
S
C
I
P
Q
R
H
T
Site 87
T920
S
C
I
P
Q
R
H
T
H
T
S
R
K
K
H
Site 88
T922
I
P
Q
R
H
T
H
T
S
R
K
K
H
T
L
Site 89
S923
P
Q
R
H
T
H
T
S
R
K
K
H
T
L
E
Site 90
Y942
T
R
E
N
P
Q
E
Y
P
D
F
Y
D
F
S
Site 91
Y946
P
Q
E
Y
P
D
F
Y
D
F
S
N
A
A
C
Site 92
S956
S
N
A
A
C
R
P
S
T
P
A
L
S
R
R
Site 93
T957
N
A
A
C
R
P
S
T
P
A
L
S
R
R
T
Site 94
S961
R
P
S
T
P
A
L
S
R
R
T
P
S
P
S
Site 95
T964
T
P
A
L
S
R
R
T
P
S
P
S
Q
G
G
Site 96
S966
A
L
S
R
R
T
P
S
P
S
Q
G
G
Y
F
Site 97
S968
S
R
R
T
P
S
P
S
Q
G
G
Y
F
G
P
Site 98
Y972
P
S
P
S
Q
G
G
Y
F
G
P
D
L
Y
S
Site 99
Y978
G
Y
F
G
P
D
L
Y
S
H
N
K
A
S
P
Site 100
S979
Y
F
G
P
D
L
Y
S
H
N
K
A
S
P
S
Site 101
S984
L
Y
S
H
N
K
A
S
P
S
G
L
K
S
A
Site 102
S986
S
H
N
K
A
S
P
S
G
L
K
S
A
Y
L
Site 103
S990
A
S
P
S
G
L
K
S
A
Y
L
P
G
Q
T
Site 104
Y992
P
S
G
L
K
S
A
Y
L
P
G
Q
T
S
P
Site 105
S998
A
Y
L
P
G
Q
T
S
P
K
K
Q
E
E
A
Site 106
Y1009
Q
E
E
A
R
R
E
Y
P
L
S
P
D
G
H
Site 107
S1012
A
R
R
E
Y
P
L
S
P
D
G
H
L
H
R
Site 108
S1037
V
E
Q
P
P
Q
R
S
D
F
P
L
A
A
P
Site 109
T1049
A
A
P
E
N
A
S
T
G
P
A
H
V
R
G
Site 110
T1058
P
A
H
V
R
G
R
T
A
V
E
T
D
L
T
Site 111
T1062
R
G
R
T
A
V
E
T
D
L
T
F
G
L
T
Site 112
T1065
T
A
V
E
T
D
L
T
F
G
L
T
P
N
R
Site 113
T1069
T
D
L
T
F
G
L
T
P
N
R
P
S
L
S
Site 114
S1074
G
L
T
P
N
R
P
S
L
S
A
C
S
S
E
Site 115
S1076
T
P
N
R
P
S
L
S
A
C
S
S
E
A
P
Site 116
S1080
P
S
L
S
A
C
S
S
E
A
P
E
E
R
S
Site 117
S1087
S
E
A
P
E
E
R
S
G
R
R
L
A
D
S
Site 118
S1094
S
G
R
R
L
A
D
S
E
S
L
G
H
G
A
Site 119
S1096
R
R
L
A
D
S
E
S
L
G
H
G
A
Q
R
Site 120
T1105
G
H
G
A
Q
R
N
T
D
L
E
R
E
D
S
Site 121
S1112
T
D
L
E
R
E
D
S
I
S
R
G
R
R
S
Site 122
S1114
L
E
R
E
D
S
I
S
R
G
R
R
S
P
S
Site 123
S1119
S
I
S
R
G
R
R
S
P
S
K
P
D
F
L
Site 124
S1121
S
R
G
R
R
S
P
S
K
P
D
F
L
Y
K
Site 125
Y1127
P
S
K
P
D
F
L
Y
K
K
S
A
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation