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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CALCOCO1
Full Name:
Calcium-binding and coiled-coil domain-containing protein 1
Alias:
CACO1; Calcium binding and coiled-coil domain 1; Calcium binding and coiled-coil domain 1, isoform CRA_b; Calphoglin; Cocoa; Coiled-coil coactivator protein; Coiled-coil leucine zipper coactivator 1; EESP2436; Inorganic pyrophosphatase activator; KIAA1536; Putative uncharacterized protein DKFZp434P097; Sarcoma antigen NY-SAR-3
Type:
Nuclear receptor co-regulator
Mass (Da):
77318
Number AA:
691
UniProt ID:
Q9P1Z2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0030518
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
E
S
P
L
S
R
A
P
S
R
G
G
Site 2
S11
S
P
L
S
R
A
P
S
R
G
G
V
N
F
L
Site 3
T23
N
F
L
N
V
A
R
T
Y
I
P
N
T
K
V
Site 4
Y24
F
L
N
V
A
R
T
Y
I
P
N
T
K
V
E
Site 5
Y34
N
T
K
V
E
C
H
Y
T
L
P
P
G
T
M
Site 6
T35
T
K
V
E
C
H
Y
T
L
P
P
G
T
M
P
Site 7
T40
H
Y
T
L
P
P
G
T
M
P
S
A
S
D
W
Site 8
S45
P
G
T
M
P
S
A
S
D
W
I
G
I
F
K
Site 9
Y61
E
A
A
C
V
R
D
Y
H
T
F
V
W
S
S
Site 10
S67
D
Y
H
T
F
V
W
S
S
V
P
E
S
T
T
Site 11
S68
Y
H
T
F
V
W
S
S
V
P
E
S
T
T
D
Site 12
S72
V
W
S
S
V
P
E
S
T
T
D
G
S
P
I
Site 13
T73
W
S
S
V
P
E
S
T
T
D
G
S
P
I
H
Site 14
S77
P
E
S
T
T
D
G
S
P
I
H
T
S
V
Q
Site 15
T81
T
D
G
S
P
I
H
T
S
V
Q
F
Q
A
S
Site 16
S82
D
G
S
P
I
H
T
S
V
Q
F
Q
A
S
Y
Site 17
S88
T
S
V
Q
F
Q
A
S
Y
L
P
K
P
G
A
Site 18
Y89
S
V
Q
F
Q
A
S
Y
L
P
K
P
G
A
Q
Site 19
Y98
P
K
P
G
A
Q
L
Y
Q
F
R
Y
V
N
R
Site 20
Y102
A
Q
L
Y
Q
F
R
Y
V
N
R
Q
G
Q
V
Site 21
S113
Q
G
Q
V
C
G
Q
S
P
P
F
Q
F
R
E
Site 22
S156
L
Q
N
Q
L
D
E
S
Q
Q
E
R
N
D
L
Site 23
T175
L
Q
L
E
G
Q
V
T
E
L
R
S
R
V
Q
Site 24
S208
Q
Y
K
G
I
S
R
S
H
G
E
I
T
E
E
Site 25
T213
S
R
S
H
G
E
I
T
E
E
R
D
I
L
S
Site 26
S220
T
E
E
R
D
I
L
S
R
Q
Q
G
D
H
V
Site 27
S241
E
D
D
I
Q
T
I
S
E
K
V
L
T
K
E
Site 28
T246
T
I
S
E
K
V
L
T
K
E
V
E
L
D
R
Site 29
T257
E
L
D
R
L
R
D
T
V
K
A
L
T
R
E
Site 30
S305
L
D
L
K
E
A
K
S
W
Q
E
E
Q
S
A
Site 31
T327
K
V
A
Q
M
K
D
T
L
G
Q
A
Q
Q
R
Site 32
S354
G
A
Q
E
L
A
A
S
S
Q
Q
K
A
T
L
Site 33
S368
L
L
G
E
E
L
A
S
A
A
A
A
R
D
R
Site 34
T376
A
A
A
A
R
D
R
T
I
A
E
L
H
R
S
Site 35
S383
T
I
A
E
L
H
R
S
R
L
E
V
A
E
V
Site 36
S409
K
E
E
K
C
Q
W
S
K
E
R
A
G
L
L
Site 37
S418
E
R
A
G
L
L
Q
S
V
E
A
E
K
D
K
Site 38
S460
E
L
A
R
E
K
D
S
S
L
V
Q
L
S
E
Site 39
S461
L
A
R
E
K
D
S
S
L
V
Q
L
S
E
S
Site 40
S466
D
S
S
L
V
Q
L
S
E
S
K
R
E
L
T
Site 41
S468
S
L
V
Q
L
S
E
S
K
R
E
L
T
E
L
Site 42
T473
S
E
S
K
R
E
L
T
E
L
R
S
A
L
R
Site 43
S477
R
E
L
T
E
L
R
S
A
L
R
V
L
Q
K
Site 44
Y499
E
K
Q
E
L
L
E
Y
M
R
K
L
E
A
R
Site 45
T520
E
K
W
N
E
D
A
T
T
E
D
E
E
A
A
Site 46
T521
K
W
N
E
D
A
T
T
E
D
E
E
A
A
V
Site 47
T537
L
S
C
P
A
A
L
T
D
S
E
D
E
S
P
Site 48
S539
C
P
A
A
L
T
D
S
E
D
E
S
P
E
D
Site 49
S543
L
T
D
S
E
D
E
S
P
E
D
M
R
L
P
Site 50
Y552
E
D
M
R
L
P
P
Y
G
L
C
E
R
G
D
Site 51
S562
C
E
R
G
D
P
G
S
S
P
A
G
P
R
E
Site 52
S563
E
R
G
D
P
G
S
S
P
A
G
P
R
E
A
Site 53
S571
P
A
G
P
R
E
A
S
P
L
V
V
I
S
Q
Site 54
S583
I
S
Q
P
A
P
I
S
P
H
L
S
G
P
A
Site 55
S587
A
P
I
S
P
H
L
S
G
P
A
E
D
S
S
Site 56
S593
L
S
G
P
A
E
D
S
S
S
D
S
E
A
E
Site 57
S594
S
G
P
A
E
D
S
S
S
D
S
E
A
E
D
Site 58
S595
G
P
A
E
D
S
S
S
D
S
E
A
E
D
E
Site 59
S597
A
E
D
S
S
S
D
S
E
A
E
D
E
K
S
Site 60
S604
S
E
A
E
D
E
K
S
V
L
M
A
A
V
Q
Site 61
Y629
P
E
L
G
S
A
F
Y
D
M
A
S
G
F
T
Site 62
T639
A
S
G
F
T
V
G
T
L
S
E
T
S
T
G
Site 63
S641
G
F
T
V
G
T
L
S
E
T
S
T
G
G
P
Site 64
T645
G
T
L
S
E
T
S
T
G
G
P
A
T
P
T
Site 65
T650
T
S
T
G
G
P
A
T
P
T
W
K
E
C
P
Site 66
T652
T
G
G
P
A
T
P
T
W
K
E
C
P
I
C
Site 67
S667
K
E
R
F
P
A
E
S
D
K
D
A
L
E
D
Site 68
T684
D
G
H
F
F
F
S
T
Q
D
P
F
T
F
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation