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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM63C
Full Name:
Transmembrane protein 63C
Alias:
Type:
Mass (Da):
93317
Number AA:
806
UniProt ID:
Q9P1W3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
A
S
P
D
D
L
S
T
G
G
R
L
Q
N
Site 2
T10
A
S
P
D
D
L
S
T
G
G
R
L
Q
N
M
Site 3
T18
G
G
R
L
Q
N
M
T
V
D
E
C
F
Q
S
Site 4
S25
T
V
D
E
C
F
Q
S
R
N
T
V
L
Q
G
Site 5
T28
E
C
F
Q
S
R
N
T
V
L
Q
G
Q
P
F
Site 6
S77
A
L
L
I
H
N
D
S
L
T
S
L
I
Y
G
Site 7
T79
L
I
H
N
D
S
L
T
S
L
I
Y
G
E
Q
Site 8
S80
I
H
N
D
S
L
T
S
L
I
Y
G
E
Q
S
Site 9
Y83
D
S
L
T
S
L
I
Y
G
E
Q
S
E
K
T
Site 10
S87
S
L
I
Y
G
E
Q
S
E
K
T
S
P
S
E
Site 11
T90
Y
G
E
Q
S
E
K
T
S
P
S
E
T
S
L
Site 12
S91
G
E
Q
S
E
K
T
S
P
S
E
T
S
L
E
Site 13
S93
Q
S
E
K
T
S
P
S
E
T
S
L
E
M
E
Site 14
S96
K
T
S
P
S
E
T
S
L
E
M
E
R
R
D
Site 15
S162
L
P
I
N
Y
T
G
S
V
L
D
W
S
S
H
Site 16
S167
T
G
S
V
L
D
W
S
S
H
F
A
R
T
T
Site 17
S168
G
S
V
L
D
W
S
S
H
F
A
R
T
T
I
Site 18
T174
S
S
H
F
A
R
T
T
I
V
N
V
S
T
E
Site 19
T180
T
T
I
V
N
V
S
T
E
S
K
L
L
W
L
Site 20
S215
L
G
F
A
P
R
N
S
Q
K
V
T
R
T
L
Site 21
Y226
T
R
T
L
M
I
T
Y
V
P
K
D
I
E
D
Site 22
Y245
I
K
H
F
H
E
A
Y
P
G
S
V
V
T
R
Site 23
Y279
A
M
R
G
R
L
F
Y
T
A
K
A
K
K
T
Site 24
S318
V
D
A
E
Q
Y
Y
S
E
L
E
E
Q
L
T
Site 25
T325
S
E
L
E
E
Q
L
T
D
E
F
N
A
E
L
Site 26
S350
I
F
V
T
F
Q
D
S
R
M
A
K
R
V
R
Site 27
Y360
A
K
R
V
R
K
D
Y
K
Y
V
Q
C
G
V
Site 28
Y362
R
V
R
K
D
Y
K
Y
V
Q
C
G
V
Q
P
Site 29
T376
P
Q
Q
S
S
V
T
T
I
V
K
S
Y
Y
W
Site 30
Y382
T
T
I
V
K
S
Y
Y
W
R
V
T
M
A
P
Site 31
Y437
I
M
N
T
I
D
M
Y
N
V
T
R
P
I
E
Site 32
T482
A
F
L
E
A
H
W
T
R
S
S
Q
N
L
V
Site 33
S484
L
E
A
H
W
T
R
S
S
Q
N
L
V
M
V
Site 34
Y525
R
W
L
F
D
I
Y
Y
L
E
Q
A
S
I
R
Site 35
S577
Y
S
T
R
L
F
F
S
R
S
E
P
E
R
V
Site 36
S579
T
R
L
F
F
S
R
S
E
P
E
R
V
N
I
Site 37
Y637
M
K
H
L
T
D
R
Y
N
M
Y
Y
S
F
A
Site 38
Y640
L
T
D
R
Y
N
M
Y
Y
S
F
A
P
T
K
Site 39
Y641
T
D
R
Y
N
M
Y
Y
S
F
A
P
T
K
L
Site 40
Y715
K
L
R
M
V
A
D
Y
E
P
E
E
E
E
I
Site 41
T724
P
E
E
E
E
I
Q
T
V
F
D
M
E
P
S
Site 42
S731
T
V
F
D
M
E
P
S
S
T
S
S
T
P
T
Site 43
S732
V
F
D
M
E
P
S
S
T
S
S
T
P
T
S
Site 44
T733
F
D
M
E
P
S
S
T
S
S
T
P
T
S
L
Site 45
S734
D
M
E
P
S
S
T
S
S
T
P
T
S
L
L
Site 46
S735
M
E
P
S
S
T
S
S
T
P
T
S
L
L
Y
Site 47
T736
E
P
S
S
T
S
S
T
P
T
S
L
L
Y
V
Site 48
T738
S
S
T
S
S
T
P
T
S
L
L
Y
V
A
T
Site 49
T755
Q
E
P
E
L
N
L
T
P
A
S
S
P
A
R
Site 50
S758
E
L
N
L
T
P
A
S
S
P
A
R
H
T
Y
Site 51
S759
L
N
L
T
P
A
S
S
P
A
R
H
T
Y
G
Site 52
T764
A
S
S
P
A
R
H
T
Y
G
T
M
N
N
Q
Site 53
Y765
S
S
P
A
R
H
T
Y
G
T
M
N
N
Q
P
Site 54
T767
P
A
R
H
T
Y
G
T
M
N
N
Q
P
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation