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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CXXC1
Full Name:
CpG-binding protein
Alias:
CFP1; CGBP; CpG binding protein; CXCC1; CXXC finger 1 (PHD domain); DNA-binding protein with PHD finger and CXXC domain; HsT2645; PCCX1; PHF18; SPP1; ZCGPC1; Zinc finger, CpG binding-type containing 1
Type:
Transcription factor
Mass (Da):
75712
Number AA:
656
UniProt ID:
Q9P0U4
International Prot ID:
IPI00292445
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0035097
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0016563
GO:0045322
PhosphoSite+
KinaseNET
Biological Process:
GO:0051568
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
G
D
G
S
D
P
E
P
P
D
A
Site 2
S17
P
P
D
A
G
E
D
S
K
S
E
N
G
E
N
Site 3
S19
D
A
G
E
D
S
K
S
E
N
G
E
N
A
P
Site 4
Y28
N
G
E
N
A
P
I
Y
C
I
C
R
K
P
D
Site 5
Y69
A
K
A
I
R
E
W
Y
C
R
E
C
R
E
K
Site 6
S89
I
R
Y
R
H
K
K
S
R
E
R
D
G
N
E
Site 7
S99
R
D
G
N
E
R
D
S
S
E
P
R
D
E
G
Site 8
S100
D
G
N
E
R
D
S
S
E
P
R
D
E
G
G
Site 9
S124
D
L
Q
R
R
A
G
S
G
T
G
V
G
A
M
Site 10
T126
Q
R
R
A
G
S
G
T
G
V
G
A
M
L
A
Site 11
S136
G
A
M
L
A
R
G
S
A
S
P
H
K
S
S
Site 12
S138
M
L
A
R
G
S
A
S
P
H
K
S
S
P
Q
Site 13
S142
G
S
A
S
P
H
K
S
S
P
Q
P
L
V
A
Site 14
S143
S
A
S
P
H
K
S
S
P
Q
P
L
V
A
T
Site 15
T150
S
P
Q
P
L
V
A
T
P
S
Q
H
H
Q
Q
Site 16
S152
Q
P
L
V
A
T
P
S
Q
H
H
Q
Q
Q
Q
Site 17
S215
C
Q
L
R
A
R
E
S
Y
K
Y
F
P
S
S
Site 18
Y216
Q
L
R
A
R
E
S
Y
K
Y
F
P
S
S
L
Site 19
Y218
R
A
R
E
S
Y
K
Y
F
P
S
S
L
S
P
Site 20
S221
E
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
Site 21
S222
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
S
Site 22
S224
K
Y
F
P
S
S
L
S
P
V
T
P
S
E
S
Site 23
T227
P
S
S
L
S
P
V
T
P
S
E
S
L
P
R
Site 24
S229
S
L
S
P
V
T
P
S
E
S
L
P
R
P
R
Site 25
S231
S
P
V
T
P
S
E
S
L
P
R
P
R
R
P
Site 26
T241
R
P
R
R
P
L
P
T
Q
Q
Q
P
Q
P
S
Site 27
S248
T
Q
Q
Q
P
Q
P
S
Q
K
L
G
R
I
R
Site 28
T265
E
G
A
V
A
S
S
T
V
K
E
P
P
E
A
Site 29
T275
E
P
P
E
A
T
A
T
P
E
P
L
S
D
E
Site 30
S280
T
A
T
P
E
P
L
S
D
E
D
L
P
L
D
Site 31
S308
D
H
G
L
P
W
M
S
D
T
E
E
S
P
F
Site 32
T310
G
L
P
W
M
S
D
T
E
E
S
P
F
L
D
Site 33
S313
W
M
S
D
T
E
E
S
P
F
L
D
P
A
L
Site 34
S337
V
K
R
R
E
K
K
S
E
K
K
K
E
E
R
Site 35
Y345
E
K
K
K
E
E
R
Y
K
R
H
R
Q
K
Q
Site 36
S371
A
D
A
K
D
P
A
S
L
P
Q
C
L
G
P
Site 37
S387
C
V
R
P
A
Q
P
S
S
K
Y
C
S
D
D
Site 38
S388
V
R
P
A
Q
P
S
S
K
Y
C
S
D
D
C
Site 39
Y390
P
A
Q
P
S
S
K
Y
C
S
D
D
C
G
M
Site 40
S392
Q
P
S
S
K
Y
C
S
D
D
C
G
M
K
L
Site 41
Y405
K
L
A
A
N
R
I
Y
E
I
L
P
Q
R
I
Site 42
S439
R
I
R
R
E
Q
Q
S
A
R
T
R
L
Q
E
Site 43
S472
A
V
R
E
D
E
E
S
N
E
G
D
S
D
D
Site 44
S477
E
E
S
N
E
G
D
S
D
D
T
D
L
Q
I
Site 45
T480
N
E
G
D
S
D
D
T
D
L
Q
I
F
C
V
Site 46
Y506
L
R
H
M
E
R
C
Y
A
K
Y
E
S
Q
T
Site 47
Y509
M
E
R
C
Y
A
K
Y
E
S
Q
T
S
F
G
Site 48
S511
R
C
Y
A
K
Y
E
S
Q
T
S
F
G
S
M
Site 49
S514
A
K
Y
E
S
Q
T
S
F
G
S
M
Y
P
T
Site 50
S517
E
S
Q
T
S
F
G
S
M
Y
P
T
R
I
E
Site 51
Y519
Q
T
S
F
G
S
M
Y
P
T
R
I
E
G
A
Site 52
T521
S
F
G
S
M
Y
P
T
R
I
E
G
A
T
R
Site 53
Y534
T
R
L
F
C
D
V
Y
N
P
Q
S
K
T
Y
Site 54
T540
V
Y
N
P
Q
S
K
T
Y
C
K
R
L
Q
V
Site 55
S553
Q
V
L
C
P
E
H
S
R
D
P
K
V
P
A
Site 56
Y591
K
R
Q
C
N
R
H
Y
C
W
E
K
L
R
R
Site 57
Y610
L
E
R
V
R
V
W
Y
K
L
D
E
L
F
E
Site 58
T627
R
N
V
R
T
A
M
T
N
R
A
G
L
L
A
Site 59
T647
T
I
Q
H
D
P
L
T
T
D
L
R
S
S
A
Site 60
T648
I
Q
H
D
P
L
T
T
D
L
R
S
S
A
D
Site 61
S652
P
L
T
T
D
L
R
S
S
A
D
R
_
_
_
Site 62
S653
L
T
T
D
L
R
S
S
A
D
R
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation