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Updated November 2019
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Protein Info
Short Name:
ZIM2
Full Name:
Zinc finger imprinted 2
Alias:
Type:
Mass (Da):
61164
Number AA:
527
UniProt ID:
Q9NZV7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y2
_
_
_
_
_
_
M
Y
Q
P
E
D
D
N
N
Site 2
S10
Q
P
E
D
D
N
N
S
D
V
T
S
D
D
D
Site 3
T13
D
D
N
N
S
D
V
T
S
D
D
D
M
T
R
Site 4
S14
D
N
N
S
D
V
T
S
D
D
D
M
T
R
N
Site 5
T19
V
T
S
D
D
D
M
T
R
N
R
R
E
S
S
Site 6
S25
M
T
R
N
R
R
E
S
S
P
P
H
S
V
H
Site 7
S26
T
R
N
R
R
E
S
S
P
P
H
S
V
H
S
Site 8
S30
R
E
S
S
P
P
H
S
V
H
S
F
S
G
D
Site 9
S33
S
P
P
H
S
V
H
S
F
S
G
D
R
D
W
Site 10
S35
P
H
S
V
H
S
F
S
G
D
R
D
W
D
R
Site 11
S46
D
W
D
R
R
G
R
S
R
D
M
E
P
R
D
Site 12
S56
M
E
P
R
D
R
W
S
H
T
R
N
P
R
S
Site 13
T58
P
R
D
R
W
S
H
T
R
N
P
R
S
R
M
Site 14
S63
S
H
T
R
N
P
R
S
R
M
P
P
R
D
L
Site 15
S71
R
M
P
P
R
D
L
S
L
P
V
V
A
K
T
Site 16
S79
L
P
V
V
A
K
T
S
F
E
M
D
R
E
D
Site 17
S90
D
R
E
D
D
R
D
S
R
A
Y
E
S
R
S
Site 18
Y93
D
D
R
D
S
R
A
Y
E
S
R
S
Q
D
A
Site 19
S97
S
R
A
Y
E
S
R
S
Q
D
A
E
S
Y
Q
Site 20
T118
E
D
R
K
P
H
N
T
I
Q
D
N
M
E
N
Site 21
S131
E
N
Y
R
K
L
L
S
L
G
F
L
A
Q
D
Site 22
S139
L
G
F
L
A
Q
D
S
V
P
A
E
K
R
N
Site 23
T147
V
P
A
E
K
R
N
T
E
M
L
D
N
L
P
Site 24
S155
E
M
L
D
N
L
P
S
A
G
S
Q
F
P
D
Site 25
S158
D
N
L
P
S
A
G
S
Q
F
P
D
F
K
H
Site 26
S186
E
D
V
L
V
D
F
S
P
E
E
L
S
S
L
Site 27
S192
F
S
P
E
E
L
S
S
L
S
A
A
Q
R
N
Site 28
S194
P
E
E
L
S
S
L
S
A
A
Q
R
N
L
Y
Site 29
Y201
S
A
A
Q
R
N
L
Y
R
E
V
M
L
E
N
Site 30
Y209
R
E
V
M
L
E
N
Y
R
N
L
V
S
L
G
Site 31
S214
E
N
Y
R
N
L
V
S
L
G
H
Q
F
S
K
Site 32
S220
V
S
L
G
H
Q
F
S
K
P
D
I
I
S
R
Site 33
S226
F
S
K
P
D
I
I
S
R
L
E
E
E
E
S
Site 34
S233
S
R
L
E
E
E
E
S
Y
A
M
E
T
D
S
Site 35
Y234
R
L
E
E
E
E
S
Y
A
M
E
T
D
S
R
Site 36
T243
M
E
T
D
S
R
H
T
V
I
C
Q
G
E
S
Site 37
T267
G
N
Q
E
K
L
L
T
P
I
T
M
N
D
P
Site 38
T270
E
K
L
L
T
P
I
T
M
N
D
P
K
T
L
Site 39
T276
I
T
M
N
D
P
K
T
L
T
P
E
R
S
Y
Site 40
T278
M
N
D
P
K
T
L
T
P
E
R
S
Y
G
S
Site 41
Y283
T
L
T
P
E
R
S
Y
G
S
D
E
F
E
R
Site 42
S285
T
P
E
R
S
Y
G
S
D
E
F
E
R
S
S
Site 43
S291
G
S
D
E
F
E
R
S
S
N
L
S
K
Q
S
Site 44
S292
S
D
E
F
E
R
S
S
N
L
S
K
Q
S
K
Site 45
S295
F
E
R
S
S
N
L
S
K
Q
S
K
D
P
L
Site 46
S298
S
S
N
L
S
K
Q
S
K
D
P
L
G
K
D
Site 47
T316
G
T
A
P
G
I
C
T
S
P
Q
S
A
S
Q
Site 48
S317
T
A
P
G
I
C
T
S
P
Q
S
A
S
Q
E
Site 49
S320
G
I
C
T
S
P
Q
S
A
S
Q
E
N
K
H
Site 50
S322
C
T
S
P
Q
S
A
S
Q
E
N
K
H
N
R
Site 51
T336
R
C
E
F
C
K
R
T
F
S
T
Q
V
A
L
Site 52
S338
E
F
C
K
R
T
F
S
T
Q
V
A
L
R
R
Site 53
T351
R
R
H
E
R
I
H
T
G
K
K
P
Y
E
C
Site 54
Y366
K
Q
C
A
E
A
F
Y
L
M
P
H
L
N
R
Site 55
T377
H
L
N
R
H
Q
K
T
H
S
G
R
K
T
S
Site 56
S379
N
R
H
Q
K
T
H
S
G
R
K
T
S
G
C
Site 57
T383
K
T
H
S
G
R
K
T
S
G
C
N
E
G
R
Site 58
S384
T
H
S
G
R
K
T
S
G
C
N
E
G
R
K
Site 59
Y411
R
I
H
S
Q
E
D
Y
F
E
C
F
Q
C
G
Site 60
S445
R
V
L
P
P
G
L
S
H
S
K
T
Y
L
I
Site 61
S447
L
P
P
G
L
S
H
S
K
T
Y
L
I
R
Y
Site 62
T449
P
G
L
S
H
S
K
T
Y
L
I
R
Y
Q
R
Site 63
Y454
S
K
T
Y
L
I
R
Y
Q
R
K
H
D
Y
V
Site 64
Y460
R
Y
Q
R
K
H
D
Y
V
G
E
R
A
C
Q
Site 65
S479
G
R
V
F
S
R
N
S
Y
L
I
Q
H
Y
R
Site 66
Y480
R
V
F
S
R
N
S
Y
L
I
Q
H
Y
R
T
Site 67
T489
I
Q
H
Y
R
T
H
T
Q
E
R
P
Y
Q
C
Site 68
Y494
T
H
T
Q
E
R
P
Y
Q
C
Q
L
C
G
K
Site 69
Y508
K
C
F
G
R
P
S
Y
L
T
Q
H
Y
Q
L
Site 70
T510
F
G
R
P
S
Y
L
T
Q
H
Y
Q
L
H
S
Site 71
Y513
P
S
Y
L
T
Q
H
Y
Q
L
H
S
Q
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation