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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LMCD1
Full Name:
LIM and cysteine-rich domains protein 1
Alias:
Dyxin; LIM and cysteine-rich domains 1
Type:
Nucleus protein
Mass (Da):
40833
Number AA:
365
UniProt ID:
Q9NZU5
International Prot ID:
IPI00303258
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
N
P
G
V
K
K
M
S
L
G
Q
L
Q
S
A
Site 2
T60
S
Q
E
D
H
C
L
T
S
D
L
E
D
D
R
Site 3
Y78
R
L
L
M
D
S
K
Y
S
T
L
T
A
R
V
Site 4
T80
L
M
D
S
K
Y
S
T
L
T
A
R
V
K
G
Site 5
T82
D
S
K
Y
S
T
L
T
A
R
V
K
G
G
D
Site 6
Y94
G
G
D
G
I
R
I
Y
K
R
N
R
M
I
M
Site 7
T112
I
A
T
G
K
D
P
T
F
D
T
I
T
Y
E
Site 8
T115
G
K
D
P
T
F
D
T
I
T
Y
E
W
A
P
Site 9
T117
D
P
T
F
D
T
I
T
Y
E
W
A
P
P
G
Site 10
Y118
P
T
F
D
T
I
T
Y
E
W
A
P
P
G
V
Site 11
T126
E
W
A
P
P
G
V
T
Q
K
L
G
L
Q
Y
Site 12
Y133
T
Q
K
L
G
L
Q
Y
M
E
L
I
P
K
E
Site 13
T145
P
K
E
K
Q
P
V
T
G
T
E
G
A
F
Y
Site 14
T147
E
K
Q
P
V
T
G
T
E
G
A
F
Y
R
R
Site 15
Y152
T
G
T
E
G
A
F
Y
R
R
R
Q
L
M
H
Site 16
Y164
L
M
H
Q
L
P
I
Y
D
Q
D
P
S
R
C
Site 17
S169
P
I
Y
D
Q
D
P
S
R
C
R
G
L
L
E
Site 18
S191
E
F
V
K
Q
Y
K
S
E
A
L
G
V
G
E
Site 19
T223
E
K
P
E
G
A
E
T
T
A
A
T
T
N
G
Site 20
T227
G
A
E
T
T
A
A
T
T
N
G
S
L
S
D
Site 21
S231
T
A
A
T
T
N
G
S
L
S
D
P
S
K
E
Site 22
S233
A
T
T
N
G
S
L
S
D
P
S
K
E
V
E
Site 23
S236
N
G
S
L
S
D
P
S
K
E
V
E
Y
V
C
Site 24
Y241
D
P
S
K
E
V
E
Y
V
C
E
L
C
K
G
Site 25
S254
K
G
A
A
P
P
D
S
P
V
V
Y
S
D
R
Site 26
Y258
P
P
D
S
P
V
V
Y
S
D
R
A
G
Y
N
Site 27
S259
P
D
S
P
V
V
Y
S
D
R
A
G
Y
N
K
Site 28
Y264
V
Y
S
D
R
A
G
Y
N
K
Q
W
H
P
T
Site 29
Y300
A
P
W
C
G
R
H
Y
C
E
S
L
R
P
R
Site 30
S309
E
S
L
R
P
R
C
S
G
C
D
E
I
I
F
Site 31
Y320
E
I
I
F
A
E
D
Y
Q
R
V
E
D
L
A
Site 32
T358
K
G
Q
L
L
C
P
T
C
S
K
S
K
R
S
Site 33
S360
Q
L
L
C
P
T
C
S
K
S
K
R
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation