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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OGFR
Full Name:
Opioid growth factor receptor
Alias:
7-60 protein; Zeta-type opioid receptor
Type:
Receptor, misc.
Mass (Da):
73325
Number AA:
677
UniProt ID:
Q9NZT2
International Prot ID:
IPI00021537
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016020
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004985
GO:0001653
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0001558
GO:0040008
GO:0050789
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
D
D
P
D
C
D
S
T
W
E
E
D
E
E
Site 2
T9
D
D
P
D
C
D
S
T
W
E
E
D
E
E
D
Site 3
S45
A
G
D
E
D
E
E
S
E
E
P
R
A
A
R
Site 4
S54
E
P
R
A
A
R
P
S
S
F
Q
S
R
M
T
Site 5
S55
P
R
A
A
R
P
S
S
F
Q
S
R
M
T
G
Site 6
S58
A
R
P
S
S
F
Q
S
R
M
T
G
S
R
N
Site 7
T61
S
S
F
Q
S
R
M
T
G
S
R
N
W
R
A
Site 8
Y75
A
T
R
D
M
C
R
Y
R
H
N
Y
P
D
L
Site 9
Y79
M
C
R
Y
R
H
N
Y
P
D
L
V
E
R
D
Site 10
T91
E
R
D
C
N
G
D
T
P
N
L
S
F
Y
R
Site 11
S95
N
G
D
T
P
N
L
S
F
Y
R
N
E
I
R
Site 12
Y121
L
Q
N
W
T
D
N
Y
D
L
L
E
D
N
H
Site 13
T150
N
W
H
A
K
P
L
T
L
R
E
V
E
V
F
Site 14
S159
R
E
V
E
V
F
K
S
S
Q
E
I
Q
E
R
Site 15
S160
E
V
E
V
F
K
S
S
Q
E
I
Q
E
R
L
Site 16
Y171
Q
E
R
L
V
R
A
Y
E
L
M
L
G
F
Y
Site 17
Y178
Y
E
L
M
L
G
F
Y
G
I
R
L
E
D
R
Site 18
T187
I
R
L
E
D
R
G
T
G
T
V
G
R
A
Q
Site 19
T189
L
E
D
R
G
T
G
T
V
G
R
A
Q
N
Y
Site 20
Y196
T
V
G
R
A
Q
N
Y
Q
K
R
F
Q
N
L
Site 21
T214
S
H
N
N
L
R
I
T
R
I
L
K
S
L
G
Site 22
T240
V
R
F
F
L
E
E
T
L
V
R
R
E
L
P
Site 23
S298
K
L
R
R
F
K
P
S
S
L
P
H
P
L
E
Site 24
S299
L
R
R
F
K
P
S
S
L
P
H
P
L
E
G
Site 25
S315
R
K
V
E
E
E
G
S
P
G
D
P
D
H
E
Site 26
S324
G
D
P
D
H
E
A
S
T
Q
G
R
T
C
G
Site 27
T325
D
P
D
H
E
A
S
T
Q
G
R
T
C
G
P
Site 28
T329
E
A
S
T
Q
G
R
T
C
G
P
E
H
S
K
Site 29
S335
R
T
C
G
P
E
H
S
K
G
G
G
R
V
D
Site 30
S349
D
E
G
P
Q
P
R
S
V
E
P
Q
D
A
G
Site 31
S361
D
A
G
P
L
E
R
S
Q
G
D
E
A
G
G
Site 32
S378
E
D
R
P
E
P
L
S
P
K
E
S
K
K
R
Site 33
S382
E
P
L
S
P
K
E
S
K
K
R
K
L
E
L
Site 34
S390
K
K
R
K
L
E
L
S
R
R
E
Q
P
P
T
Site 35
T397
S
R
R
E
Q
P
P
T
E
P
G
P
Q
S
A
Site 36
S403
P
T
E
P
G
P
Q
S
A
S
E
V
E
K
I
Site 37
S405
E
P
G
P
Q
S
A
S
E
V
E
K
I
A
L
Site 38
S420
N
L
E
G
C
A
L
S
Q
G
S
L
R
T
G
Site 39
S423
G
C
A
L
S
Q
G
S
L
R
T
G
T
Q
E
Site 40
T426
L
S
Q
G
S
L
R
T
G
T
Q
E
V
G
G
Site 41
T428
Q
G
S
L
R
T
G
T
Q
E
V
G
G
Q
D
Site 42
S468
V
D
E
G
A
G
D
S
A
A
V
A
S
G
G
Site 43
T478
V
A
S
G
G
A
Q
T
L
A
L
A
G
S
P
Site 44
S484
Q
T
L
A
L
A
G
S
P
A
P
S
G
H
P
Site 45
S488
L
A
G
S
P
A
P
S
G
H
P
K
A
G
H
Site 46
T504
E
N
G
V
E
E
D
T
E
G
R
T
G
P
K
Site 47
T514
R
T
G
P
K
E
G
T
P
G
S
P
S
E
T
Site 48
S517
P
K
E
G
T
P
G
S
P
S
E
T
P
G
P
Site 49
S519
E
G
T
P
G
S
P
S
E
T
P
G
P
S
P
Site 50
T521
T
P
G
S
P
S
E
T
P
G
P
S
P
A
G
Site 51
S525
P
S
E
T
P
G
P
S
P
A
G
P
A
G
D
Site 52
S537
A
G
D
E
P
A
E
S
P
S
E
T
P
G
P
Site 53
S539
D
E
P
A
E
S
P
S
E
T
P
G
P
R
P
Site 54
T541
P
A
E
S
P
S
E
T
P
G
P
R
P
A
G
Site 55
S579
D
E
P
A
E
S
P
S
E
T
P
G
P
S
P
Site 56
T581
P
A
E
S
P
S
E
T
P
G
P
S
P
A
G
Site 57
S585
P
S
E
T
P
G
P
S
P
A
G
P
T
R
D
Site 58
S597
T
R
D
E
P
A
E
S
P
S
E
T
P
G
P
Site 59
S670
L
Q
D
A
E
V
E
S
S
A
K
S
G
K
P
Site 60
S674
E
V
E
S
S
A
K
S
G
K
P
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation