PhosphoNET

           
Protein Info 
   
Short Name:  NckIPSD
Full Name:  NCK-interacting protein with SH3 domain
Alias:  AF3p21; Dia interacting protein; Dia interacting protein-1; Dia-interacting protein 1; Diaphanous protein interacting protein; Diaphanous protein-interacting protein; DIP1; DIP-1; NCK interacting protein with SH3 domain; ORF1; SH3 adapter protein SPIN90; SH3 protein interacting with Nck, 90 kDa; SPIN90; SPN90; VacA-interacting protein, 54 kDa; VIP54; WASLBP; WISH
Type:  Adaptor/scaffold
Mass (Da):  78960
Number AA:  722
UniProt ID:  Q9NZQ3
International Prot ID:  IPI00009319
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005882  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0017124  GO:0008092   PhosphoSite+ KinaseNET
Biological Process:  GO:0006607  GO:0007010  GO:0007165 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10RALYAFRSAEPNALA
Site 2S42WLAARARSGETGYVP
Site 3Y47ARSGETGYVPPAYLR
Site 4Y52TGYVPPAYLRRLQGL
Site 5Y85AMRDGGKYSLEQRGV
Site 6S86MRDGGKYSLEQRGVL
Site 7T103LIHHRKETLSRRGPS
Site 8S105HHRKETLSRRGPSAS
Site 9S110TLSRRGPSASSVAVM
Site 10S112SRRGPSASSVAVMTS
Site 11S113RRGPSASSVAVMTSS
Site 12T118ASSVAVMTSSTSDHH
Site 13S119SSVAVMTSSTSDHHL
Site 14S120SVAVMTSSTSDHHLD
Site 15T121VAVMTSSTSDHHLDA
Site 16S122AVMTSSTSDHHLDAA
Site 17S147AGFERQHSLPSSEHL
Site 18S151RQHSLPSSEHLGADG
Site 19Y161LGADGGLYQIPLPSS
Site 20S167LYQIPLPSSQIPPQP
Site 21S168YQIPLPSSQIPPQPR
Site 22T180QPRRAAPTTPPPPVK
Site 23T181PRRAAPTTPPPPVKR
Site 24S199EALMASGSGGHNTMP
Site 25T204SGSGGHNTMPSGGNS
Site 26S207GGHNTMPSGGNSVSS
Site 27S211TMPSGGNSVSSGSSV
Site 28S213PSGGNSVSSGSSVSS
Site 29S214SGGNSVSSGSSVSST
Site 30S216GNSVSSGSSVSSTSL
Site 31S217NSVSSGSSVSSTSLD
Site 32S220SSGSSVSSTSLDTLY
Site 33T221SGSSVSSTSLDTLYT
Site 34S222GSSVSSTSLDTLYTS
Site 35T225VSSTSLDTLYTSSSP
Site 36Y227STSLDTLYTSSSPSE
Site 37T228TSLDTLYTSSSPSEP
Site 38S229SLDTLYTSSSPSEPG
Site 39S230LDTLYTSSSPSEPGS
Site 40S231DTLYTSSSPSEPGSS
Site 41S233LYTSSSPSEPGSSCS
Site 42S237SSPSEPGSSCSPTPP
Site 43S238SPSEPGSSCSPTPPP
Site 44S240SEPGSSCSPTPPPVP
Site 45T242PGSSCSPTPPPVPRR
Site 46T251PPVPRRGTHTTVSQV
Site 47T253VPRRGTHTTVSQVQP
Site 48T254PRRGTHTTVSQVQPP
Site 49S256RGTHTTVSQVQPPPS
Site 50S263SQVQPPPSKASAPEP
Site 51T278PAEEEVATGTTSASD
Site 52S282EVATGTTSASDDLEA
Site 53S284ATGTTSASDDLEALG
Site 54T292DDLEALGTLSLGTTE
Site 55S294LEALGTLSLGTTEEK
Site 56T298GTLSLGTTEEKAAAE
Site 57T324MELVRRNTGLSHELC
Site 58S327VRRNTGLSHELCRVA
Site 59S367LVEGKDLSMALPSGQ
Site 60Y404QQRSWALYEDEGVIR
Site 61S455YQMEHRASLRLLLLK
Site 62T495ARDMQTDTQDHQKLC
Site 63Y520SMGEAVPYAHYEHLG
Site 64Y523EAVPYAHYEHLGTPF
Site 65T546EDGLPLDTTEQLPDL
Site 66T547DGLPLDTTEQLPDLC
Site 67S613HEPQPPHSVLKFLQD
Site 68S651VRHIADLSPGDKLRM
Site 69Y660GDKLRMEYLSLMHAI
Site 70Y673AIVRTTPYLQHRHRL
Site 71S697ILNEEETSPQCQMDR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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