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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EHD2
Full Name:
EH domain-containing protein 2
Alias:
EH-domain containing 2; EH-domain containing protein 2; PAST2
Type:
Vesicle protein
Mass (Da):
61161
Number AA:
543
UniProt ID:
Q9NZN4
International Prot ID:
IPI00100980
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
GO:0019898
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005525
GO:0003924
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
Q
Q
P
E
A
I
R
T
V
T
S
A
L
K
E
Site 2
T22
P
E
A
I
R
T
V
T
S
A
L
K
E
L
Y
Site 3
S23
E
A
I
R
T
V
T
S
A
L
K
E
L
Y
R
Site 4
S47
Y
R
F
G
A
F
H
S
P
A
L
E
D
A
D
Site 5
S73
Q
Y
S
T
G
K
T
S
F
I
Q
Y
L
L
E
Site 6
Y77
G
K
T
S
F
I
Q
Y
L
L
E
Q
E
V
P
Site 7
S86
L
E
Q
E
V
P
G
S
R
V
G
P
E
P
T
Site 8
T105
V
A
V
M
H
G
D
T
E
G
T
V
P
G
N
Site 9
S159
I
D
T
P
G
I
L
S
G
A
K
Q
R
V
S
Site 10
S166
S
G
A
K
Q
R
V
S
R
G
Y
D
F
P
A
Site 11
Y169
K
Q
R
V
S
R
G
Y
D
F
P
A
V
L
R
Site 12
S197
D
A
H
K
L
E
I
S
D
E
F
S
E
A
I
Site 13
Y253
T
P
E
V
L
R
V
Y
I
G
S
F
W
S
Q
Site 14
Y309
R
L
V
R
V
H
A
Y
I
I
S
Y
L
K
K
Site 15
Y313
V
H
A
Y
I
I
S
Y
L
K
K
E
M
P
S
Site 16
S349
I
Q
L
E
H
H
I
S
P
G
D
F
P
D
C
Site 17
T369
L
L
M
A
H
D
F
T
K
F
H
S
L
K
P
Site 18
S373
H
D
F
T
K
F
H
S
L
K
P
K
L
L
E
Site 19
S404
L
R
Q
E
E
L
E
S
T
E
V
G
V
Q
G
Site 20
T405
R
Q
E
E
L
E
S
T
E
V
G
V
Q
G
G
Site 21
S438
M
E
D
G
E
E
G
S
D
D
E
A
E
W
V
Site 22
T447
D
E
A
E
W
V
V
T
K
D
K
S
K
Y
D
Site 23
S451
W
V
V
T
K
D
K
S
K
Y
D
E
I
F
Y
Site 24
Y453
V
T
K
D
K
S
K
Y
D
E
I
F
Y
N
L
Site 25
Y458
S
K
Y
D
E
I
F
Y
N
L
A
P
A
D
G
Site 26
S468
A
P
A
D
G
K
L
S
G
S
K
A
K
T
W
Site 27
S470
A
D
G
K
L
S
G
S
K
A
K
T
W
M
V
Site 28
T474
L
S
G
S
K
A
K
T
W
M
V
G
T
K
L
Site 29
S484
V
G
T
K
L
P
N
S
V
L
G
R
I
W
K
Site 30
S493
L
G
R
I
W
K
L
S
D
V
D
R
D
G
M
Site 31
S534
P
R
R
L
V
P
P
S
K
R
R
H
K
G
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation