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Updated November 2019
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Protein Info
Short Name:
GLTSCR1
Full Name:
Glioma tumor suppressor candidate region gene 1 protein
Alias:
Glioma tumor suppressor candidate region gene 1; GSCR1
Type:
Unknown function
Mass (Da):
152993
Number AA:
1509
UniProt ID:
Q9NZM4
International Prot ID:
IPI00024568
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
H
G
S
E
K
L
D
S
D
D
L
L
D
N
P
Site 2
S43
D
N
P
G
E
A
Q
S
A
F
Y
E
G
P
G
Site 3
Y46
G
E
A
Q
S
A
F
Y
E
G
P
G
L
H
V
Site 4
S84
L
E
D
D
I
L
G
S
P
A
T
G
G
G
G
Site 5
T87
D
I
L
G
S
P
A
T
G
G
G
G
G
G
S
Site 6
S94
T
G
G
G
G
G
G
S
G
G
A
D
Q
P
C
Site 7
S107
P
C
D
I
L
Q
Q
S
L
Q
E
A
N
I
T
Site 8
T114
S
L
Q
E
A
N
I
T
E
Q
T
L
E
A
E
Site 9
T133
L
G
P
F
Q
L
P
T
L
Q
P
A
D
G
G
Site 10
S221
L
Q
G
L
P
N
G
S
P
G
G
A
T
A
A
Site 11
S265
P
V
S
G
Y
L
A
S
A
A
G
P
S
E
P
Site 12
S277
S
E
P
V
T
L
A
S
A
G
V
S
P
Q
G
Site 13
T317
A
G
A
A
S
A
P
T
G
T
P
S
G
Q
P
Site 14
T319
A
A
S
A
P
T
G
T
P
S
G
Q
P
L
A
Site 15
S321
S
A
P
T
G
T
P
S
G
Q
P
L
A
V
A
Site 16
T347
P
N
V
I
L
H
R
T
P
T
P
I
Q
P
K
Site 17
T349
V
I
L
H
R
T
P
T
P
I
Q
P
K
P
A
Site 18
Y364
G
V
L
P
P
K
L
Y
Q
L
T
P
K
P
F
Site 19
T367
P
P
K
L
Y
Q
L
T
P
K
P
F
A
P
A
Site 20
T398
P
K
A
P
Q
N
L
T
F
M
A
A
G
K
A
Site 21
S444
P
Q
P
P
G
A
L
S
K
P
M
S
V
H
L
Site 22
S448
G
A
L
S
K
P
M
S
V
H
L
L
N
Q
G
Site 23
S565
P
V
S
L
A
A
G
S
L
P
T
Q
S
Q
P
Site 24
S570
A
G
S
L
P
T
Q
S
Q
P
A
P
A
G
P
Site 25
T607
D
G
L
V
Q
P
A
T
P
A
A
A
T
G
E
Site 26
T652
Q
Q
P
P
Q
A
P
T
P
Q
A
A
A
P
P
Site 27
T663
A
A
P
P
Q
A
T
T
P
Q
P
S
P
G
L
Site 28
S667
Q
A
T
T
P
Q
P
S
P
G
L
A
S
S
P
Site 29
S673
P
S
P
G
L
A
S
S
P
E
K
I
V
L
G
Site 30
T686
L
G
Q
P
P
S
A
T
P
T
A
I
L
T
Q
Site 31
T688
Q
P
P
S
A
T
P
T
A
I
L
T
Q
D
S
Site 32
S705
M
F
L
P
Q
E
R
S
Q
Q
P
L
S
A
E
Site 33
S710
E
R
S
Q
Q
P
L
S
A
E
G
P
H
L
S
Site 34
T737
A
Q
D
P
A
P
A
T
P
V
A
K
G
A
G
Site 35
S752
L
G
P
Q
A
P
D
S
Q
A
S
P
A
P
A
Site 36
S755
Q
A
P
D
S
Q
A
S
P
A
P
A
P
Q
I
Site 37
S774
P
L
K
G
P
G
P
S
S
S
P
S
L
P
H
Site 38
S775
L
K
G
P
G
P
S
S
S
P
S
L
P
H
Q
Site 39
S776
K
G
P
G
P
S
S
S
P
S
L
P
H
Q
A
Site 40
S778
P
G
P
S
S
S
P
S
L
P
H
Q
A
P
L
Site 41
S788
H
Q
A
P
L
G
D
S
P
H
L
P
S
P
H
Site 42
S793
G
D
S
P
H
L
P
S
P
H
P
T
R
P
P
Site 43
T797
H
L
P
S
P
H
P
T
R
P
P
S
R
P
P
Site 44
S801
P
H
P
T
R
P
P
S
R
P
P
S
R
P
Q
Site 45
S805
R
P
P
S
R
P
P
S
R
P
Q
S
V
S
R
Site 46
S809
R
P
P
S
R
P
Q
S
V
S
R
P
P
S
E
Site 47
S811
P
S
R
P
Q
S
V
S
R
P
P
S
E
P
P
Site 48
S815
Q
S
V
S
R
P
P
S
E
P
P
L
H
P
C
Site 49
S848
L
G
V
P
P
P
A
S
N
P
A
P
T
A
P
Site 50
S866
Q
P
P
L
R
P
Q
S
Q
P
P
E
G
P
L
Site 51
S882
P
A
P
H
L
P
P
S
S
T
S
S
A
V
A
Site 52
S883
A
P
H
L
P
P
S
S
T
S
S
A
V
A
S
Site 53
T884
P
H
L
P
P
S
S
T
S
S
A
V
A
S
S
Site 54
S885
H
L
P
P
S
S
T
S
S
A
V
A
S
S
S
Site 55
S886
L
P
P
S
S
T
S
S
A
V
A
S
S
S
E
Site 56
S890
S
T
S
S
A
V
A
S
S
S
E
T
S
S
R
Site 57
S891
T
S
S
A
V
A
S
S
S
E
T
S
S
R
L
Site 58
S892
S
S
A
V
A
S
S
S
E
T
S
S
R
L
P
Site 59
T894
A
V
A
S
S
S
E
T
S
S
R
L
P
A
P
Site 60
S895
V
A
S
S
S
E
T
S
S
R
L
P
A
P
T
Site 61
S896
A
S
S
S
E
T
S
S
R
L
P
A
P
T
P
Site 62
T902
S
S
R
L
P
A
P
T
P
S
D
F
Q
L
Q
Site 63
S904
R
L
P
A
P
T
P
S
D
F
Q
L
Q
F
P
Site 64
S913
F
Q
L
Q
F
P
P
S
Q
G
P
H
K
S
P
Site 65
S919
P
S
Q
G
P
H
K
S
P
T
P
P
P
T
L
Site 66
T921
Q
G
P
H
K
S
P
T
P
P
P
T
L
H
L
Site 67
T925
K
S
P
T
P
P
P
T
L
H
L
V
P
E
P
Site 68
T942
P
P
P
P
P
P
R
T
F
Q
M
V
T
T
P
Site 69
T948
R
T
F
Q
M
V
T
T
P
F
P
A
L
P
Q
Site 70
S986
A
P
A
A
P
Q
T
S
T
S
L
G
P
L
T
Site 71
S988
A
A
P
Q
T
S
T
S
L
G
P
L
T
S
P
Site 72
S1007
L
V
S
G
Q
A
P
S
G
T
P
T
A
P
S
Site 73
T1009
S
G
Q
A
P
S
G
T
P
T
A
P
S
H
A
Site 74
T1011
Q
A
P
S
G
T
P
T
A
P
S
H
A
P
A
Site 75
S1014
S
G
T
P
T
A
P
S
H
A
P
A
P
A
P
Site 76
S1053
N
V
A
K
A
A
S
S
G
P
G
K
P
S
G
Site 77
S1059
S
S
G
P
G
K
P
S
G
L
Q
Y
E
S
K
Site 78
Y1063
G
K
P
S
G
L
Q
Y
E
S
K
L
S
G
L
Site 79
S1065
P
S
G
L
Q
Y
E
S
K
L
S
G
L
K
K
Site 80
S1068
L
Q
Y
E
S
K
L
S
G
L
K
K
P
P
T
Site 81
T1075
S
G
L
K
K
P
P
T
L
Q
P
S
K
E
A
Site 82
Y1100
G
S
V
L
H
P
D
Y
K
T
A
F
P
S
F
Site 83
T1102
V
L
H
P
D
Y
K
T
A
F
P
S
F
E
D
Site 84
S1106
D
Y
K
T
A
F
P
S
F
E
D
A
L
H
R
Site 85
Y1117
A
L
H
R
L
L
P
Y
H
V
Y
Q
G
A
L
Site 86
Y1120
R
L
L
P
Y
H
V
Y
Q
G
A
L
P
S
P
Site 87
S1126
V
Y
Q
G
A
L
P
S
P
S
D
Y
H
K
V
Site 88
S1128
Q
G
A
L
P
S
P
S
D
Y
H
K
V
D
E
Site 89
Y1130
A
L
P
S
P
S
D
Y
H
K
V
D
E
E
F
Site 90
T1139
K
V
D
E
E
F
E
T
V
S
T
Q
L
L
K
Site 91
T1142
E
E
F
E
T
V
S
T
Q
L
L
K
R
T
Q
Site 92
S1163
R
L
L
L
L
E
E
S
R
R
V
S
P
S
A
Site 93
S1167
L
E
E
S
R
R
V
S
P
S
A
E
M
V
M
Site 94
S1169
E
S
R
R
V
S
P
S
A
E
M
V
M
I
D
Site 95
T1186
F
I
Q
E
E
K
T
T
L
A
L
D
K
Q
L
Site 96
Y1201
A
K
E
K
P
D
E
Y
V
S
S
S
R
S
L
Site 97
S1203
E
K
P
D
E
Y
V
S
S
S
R
S
L
G
L
Site 98
S1204
K
P
D
E
Y
V
S
S
S
R
S
L
G
L
P
Site 99
S1205
P
D
E
Y
V
S
S
S
R
S
L
G
L
P
I
Site 100
S1216
G
L
P
I
A
A
S
S
E
G
H
R
L
P
G
Site 101
S1228
L
P
G
H
G
P
L
S
S
S
A
P
G
A
S
Site 102
S1229
P
G
H
G
P
L
S
S
S
A
P
G
A
S
T
Site 103
S1230
G
H
G
P
L
S
S
S
A
P
G
A
S
T
Q
Site 104
S1235
S
S
S
A
P
G
A
S
T
Q
P
P
P
H
L
Site 105
T1236
S
S
A
P
G
A
S
T
Q
P
P
P
H
L
P
Site 106
S1256
R
H
G
G
A
G
G
S
P
S
V
T
W
A
R
Site 107
S1258
G
G
A
G
G
S
P
S
V
T
W
A
R
A
S
Site 108
T1260
A
G
G
S
P
S
V
T
W
A
R
A
S
S
S
Site 109
S1265
S
V
T
W
A
R
A
S
S
S
L
S
S
S
S
Site 110
S1266
V
T
W
A
R
A
S
S
S
L
S
S
S
S
S
Site 111
S1267
T
W
A
R
A
S
S
S
L
S
S
S
S
S
S
Site 112
S1269
A
R
A
S
S
S
L
S
S
S
S
S
S
S
S
Site 113
S1270
R
A
S
S
S
L
S
S
S
S
S
S
S
S
A
Site 114
S1271
A
S
S
S
L
S
S
S
S
S
S
S
S
A
A
Site 115
S1272
S
S
S
L
S
S
S
S
S
S
S
S
A
A
S
Site 116
S1273
S
S
L
S
S
S
S
S
S
S
S
A
A
S
S
Site 117
S1274
S
L
S
S
S
S
S
S
S
S
A
A
S
S
L
Site 118
S1275
L
S
S
S
S
S
S
S
S
A
A
S
S
L
D
Site 119
S1276
S
S
S
S
S
S
S
S
A
A
S
S
L
D
A
Site 120
S1279
S
S
S
S
S
A
A
S
S
L
D
A
D
E
D
Site 121
S1280
S
S
S
S
A
A
S
S
L
D
A
D
E
D
G
Site 122
S1291
D
E
D
G
P
M
P
S
R
N
R
P
P
I
K
Site 123
T1299
R
N
R
P
P
I
K
T
Y
E
A
R
S
R
I
Site 124
Y1300
N
R
P
P
I
K
T
Y
E
A
R
S
R
I
G
Site 125
S1319
I
K
Q
E
A
G
L
S
K
V
V
H
N
T
A
Site 126
T1339
Q
P
P
P
P
P
A
T
L
K
V
A
E
P
P
Site 127
T1356
P
P
P
P
P
P
P
T
G
Q
M
N
G
T
V
Site 128
T1362
P
T
G
Q
M
N
G
T
V
D
H
P
P
P
A
Site 129
T1378
P
E
R
K
P
L
G
T
A
P
H
C
P
R
L
Site 130
T1390
P
R
L
P
L
R
K
T
Y
R
E
N
V
G
G
Site 131
Y1391
R
L
P
L
R
K
T
Y
R
E
N
V
G
G
P
Site 132
T1404
G
P
G
A
P
E
G
T
P
A
G
R
A
R
G
Site 133
S1413
A
G
R
A
R
G
G
S
P
A
P
L
P
A
K
Site 134
Y1440
A
A
V
E
D
E
L
Y
Q
R
M
L
K
G
P
Site 135
S1454
P
P
P
E
P
A
A
S
A
A
Q
G
T
G
D
Site 136
S1477
P
P
A
K
R
R
K
S
E
S
P
D
V
D
Q
Site 137
S1479
A
K
R
R
K
S
E
S
P
D
V
D
Q
A
S
Site 138
S1486
S
P
D
V
D
Q
A
S
F
S
S
D
S
P
Q
Site 139
S1491
Q
A
S
F
S
S
D
S
P
Q
D
D
T
L
T
Site 140
T1496
S
D
S
P
Q
D
D
T
L
T
E
H
L
Q
S
Site 141
T1498
S
P
Q
D
D
T
L
T
E
H
L
Q
S
A
I
Site 142
S1503
T
L
T
E
H
L
Q
S
A
I
D
S
I
L
N
Site 143
S1507
H
L
Q
S
A
I
D
S
I
L
N
L
Q
Q
A
Site 144
T1518
L
Q
Q
A
P
G
R
T
P
A
P
S
Y
P
H
Site 145
S1522
P
G
R
T
P
A
P
S
Y
P
H
A
A
S
A
Site 146
Y1523
G
R
T
P
A
P
S
Y
P
H
A
A
S
A
G
Site 147
S1528
P
S
Y
P
H
A
A
S
A
G
T
P
A
S
P
Site 148
T1531
P
H
A
A
S
A
G
T
P
A
S
P
P
P
L
Site 149
S1534
A
S
A
G
T
P
A
S
P
P
P
L
H
R
P
Site 150
Y1544
P
L
H
R
P
E
A
Y
P
P
S
S
H
N
G
Site 151
S1547
R
P
E
A
Y
P
P
S
S
H
N
G
G
L
G
Site 152
S1548
P
E
A
Y
P
P
S
S
H
N
G
G
L
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation