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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYOF
Full Name:
Myoferlin
Alias:
Fer-1 like protein 3; FER1L3; KIAA1207
Type:
Cell surface
Mass (Da):
234709
Number AA:
2061
UniProt ID:
Q9NZM1
International Prot ID:
IPI00021048
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0031410
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008015
GO:0006936
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
R
V
I
V
E
S
A
S
N
I
P
K
T
K
F
Site 2
T15
S
A
S
N
I
P
K
T
K
F
G
K
P
D
P
Site 3
S25
G
K
P
D
P
I
V
S
V
I
F
K
D
E
K
Site 4
T35
F
K
D
E
K
K
K
T
K
K
V
D
N
E
L
Site 5
T92
T
V
A
L
K
D
L
T
G
D
Q
S
R
S
L
Site 6
S96
K
D
L
T
G
D
Q
S
R
S
L
P
Y
K
L
Site 7
S98
L
T
G
D
Q
S
R
S
L
P
Y
K
L
I
S
Site 8
Y124
T
I
D
L
V
I
G
Y
D
P
P
S
A
P
H
Site 9
S128
V
I
G
Y
D
P
P
S
A
P
H
P
N
D
L
Site 10
S136
A
P
H
P
N
D
L
S
G
P
S
V
P
G
M
Site 11
S139
P
N
D
L
S
G
P
S
V
P
G
M
G
G
D
Site 12
T172
G
P
K
G
P
V
G
T
V
S
E
A
Q
L
A
Site 13
S174
K
G
P
V
G
T
V
S
E
A
Q
L
A
R
R
Site 14
T183
A
Q
L
A
R
R
L
T
K
V
K
N
S
R
R
Site 15
S188
R
L
T
K
V
K
N
S
R
R
M
L
S
N
K
Site 16
S193
K
N
S
R
R
M
L
S
N
K
P
Q
D
F
Q
Site 17
S212
V
I
E
G
R
Q
L
S
G
N
N
I
R
P
V
Site 18
T252
F
F
Y
N
V
N
M
T
P
S
E
L
M
D
E
Site 19
Y266
E
I
I
S
I
R
V
Y
N
S
H
S
L
R
A
Site 20
S270
I
R
V
Y
N
S
H
S
L
R
A
D
C
L
M
Site 21
Y288
K
I
D
V
G
F
V
Y
D
E
P
G
H
A
V
Site 22
T308
L
L
N
D
P
E
D
T
S
S
G
S
K
G
Y
Site 23
S309
L
N
D
P
E
D
T
S
S
G
S
K
G
Y
M
Site 24
S310
N
D
P
E
D
T
S
S
G
S
K
G
Y
M
K
Site 25
Y315
T
S
S
G
S
K
G
Y
M
K
V
S
M
F
V
Site 26
T325
V
S
M
F
V
L
G
T
G
D
E
P
P
P
E
Site 27
S340
R
R
D
R
D
N
D
S
D
D
V
E
S
N
L
Site 28
S345
N
D
S
D
D
V
E
S
N
L
L
L
P
A
G
Site 29
S378
P
Q
M
D
D
A
F
S
Q
T
V
K
E
I
F
Site 30
T380
M
D
D
A
F
S
Q
T
V
K
E
I
F
G
G
Site 31
Y443
E
K
I
K
L
T
I
Y
D
W
D
R
L
T
K
Site 32
Y458
N
D
V
V
G
T
T
Y
L
H
L
S
K
I
A
Site 33
S462
G
T
T
Y
L
H
L
S
K
I
A
A
S
G
G
Site 34
S475
G
G
E
V
E
D
F
S
S
S
G
T
G
A
A
Site 35
S476
G
E
V
E
D
F
S
S
S
G
T
G
A
A
S
Site 36
S477
E
V
E
D
F
S
S
S
G
T
G
A
A
S
Y
Site 37
T479
E
D
F
S
S
S
G
T
G
A
A
S
Y
T
V
Site 38
S483
S
S
G
T
G
A
A
S
Y
T
V
N
T
G
E
Site 39
Y484
S
G
T
G
A
A
S
Y
T
V
N
T
G
E
T
Site 40
T485
G
T
G
A
A
S
Y
T
V
N
T
G
E
T
E
Site 41
Y507
G
P
C
Y
L
N
L
Y
G
S
P
R
E
Y
T
Site 42
S509
C
Y
L
N
L
Y
G
S
P
R
E
Y
T
G
F
Site 43
Y513
L
Y
G
S
P
R
E
Y
T
G
F
P
D
P
Y
Site 44
T514
Y
G
S
P
R
E
Y
T
G
F
P
D
P
Y
D
Site 45
Y520
Y
T
G
F
P
D
P
Y
D
E
L
N
T
G
K
Site 46
Y533
G
K
G
E
G
V
A
Y
R
G
R
I
L
V
E
Site 47
T548
L
A
T
F
L
E
K
T
P
P
D
K
K
L
E
Site 48
S558
D
K
K
L
E
P
I
S
N
D
D
L
L
V
V
Site 49
Y568
D
L
L
V
V
E
K
Y
Q
R
R
R
K
Y
S
Site 50
Y574
K
Y
Q
R
R
R
K
Y
S
L
S
A
V
F
H
Site 51
S575
Y
Q
R
R
R
K
Y
S
L
S
A
V
F
H
S
Site 52
S577
R
R
R
K
Y
S
L
S
A
V
F
H
S
A
T
Site 53
Y602
F
E
V
S
I
G
N
Y
G
N
K
F
D
T
T
Site 54
T608
N
Y
G
N
K
F
D
T
T
C
K
P
L
A
S
Site 55
T609
Y
G
N
K
F
D
T
T
C
K
P
L
A
S
T
Site 56
Y619
P
L
A
S
T
T
Q
Y
S
R
A
V
F
D
G
Site 57
S620
L
A
S
T
T
Q
Y
S
R
A
V
F
D
G
N
Site 58
Y628
R
A
V
F
D
G
N
Y
Y
Y
Y
L
P
W
A
Site 59
Y629
A
V
F
D
G
N
Y
Y
Y
Y
L
P
W
A
H
Site 60
Y630
V
F
D
G
N
Y
Y
Y
Y
L
P
W
A
H
T
Site 61
T637
Y
Y
L
P
W
A
H
T
K
P
V
V
T
L
T
Site 62
T642
A
H
T
K
P
V
V
T
L
T
S
Y
W
E
D
Site 63
Y646
P
V
V
T
L
T
S
Y
W
E
D
I
S
H
R
Site 64
T669
A
M
A
E
R
L
Q
T
N
I
E
A
L
K
S
Site 65
S676
T
N
I
E
A
L
K
S
G
I
Q
G
K
I
P
Site 66
Y704
E
V
I
E
D
T
R
Y
T
L
P
L
T
E
G
Site 67
T705
V
I
E
D
T
R
Y
T
L
P
L
T
E
G
K
Site 68
T709
T
R
Y
T
L
P
L
T
E
G
K
A
N
V
T
Site 69
T716
T
E
G
K
A
N
V
T
V
L
D
T
Q
I
R
Site 70
T720
A
N
V
T
V
L
D
T
Q
I
R
K
L
R
S
Site 71
S727
T
Q
I
R
K
L
R
S
R
S
L
S
Q
I
H
Site 72
S729
I
R
K
L
R
S
R
S
L
S
Q
I
H
E
A
Site 73
S731
K
L
R
S
R
S
L
S
Q
I
H
E
A
A
V
Site 74
S742
E
A
A
V
R
M
R
S
E
A
T
D
V
K
S
Site 75
S749
S
E
A
T
D
V
K
S
T
L
A
E
I
E
D
Site 76
T765
L
D
K
L
M
Q
L
T
E
E
P
Q
N
S
M
Site 77
Y788
R
G
E
K
R
L
A
Y
A
R
I
P
A
H
Q
Site 78
Y798
I
P
A
H
Q
V
L
Y
S
T
S
G
E
N
A
Site 79
S799
P
A
H
Q
V
L
Y
S
T
S
G
E
N
A
S
Site 80
S801
H
Q
V
L
Y
S
T
S
G
E
N
A
S
G
K
Site 81
S806
S
T
S
G
E
N
A
S
G
K
Y
C
G
K
T
Site 82
T813
S
G
K
Y
C
G
K
T
Q
T
I
F
L
K
Y
Site 83
Y820
T
Q
T
I
F
L
K
Y
P
Q
E
K
N
N
G
Site 84
S851
A
V
E
K
K
F
N
S
F
A
E
G
T
F
T
Site 85
T889
R
H
K
F
S
D
V
T
G
K
I
K
L
K
R
Site 86
Y935
T
E
F
T
D
E
V
Y
Q
N
E
S
R
Y
P
Site 87
Y941
V
Y
Q
N
E
S
R
Y
P
G
G
D
W
K
P
Site 88
T952
D
W
K
P
A
E
D
T
Y
T
D
A
N
G
D
Site 89
Y953
W
K
P
A
E
D
T
Y
T
D
A
N
G
D
K
Site 90
T954
K
P
A
E
D
T
Y
T
D
A
N
G
D
K
A
Site 91
S963
A
N
G
D
K
A
A
S
P
S
E
L
T
C
P
Site 92
T968
A
A
S
P
S
E
L
T
C
P
P
G
W
E
W
Site 93
Y995
V
D
E
K
G
W
E
Y
G
I
T
I
P
P
D
Site 94
T998
K
G
W
E
Y
G
I
T
I
P
P
D
H
K
P
Site 95
S1007
P
P
D
H
K
P
K
S
W
V
A
A
E
K
M
Site 96
Y1015
W
V
A
A
E
K
M
Y
H
T
H
R
R
R
R
Site 97
T1017
A
A
E
K
M
Y
H
T
H
R
R
R
R
L
V
Site 98
T1032
R
K
R
K
K
D
L
T
Q
T
A
S
S
T
A
Site 99
S1036
K
D
L
T
Q
T
A
S
S
T
A
R
A
M
E
Site 100
Y1053
Q
D
Q
E
G
W
E
Y
A
S
L
I
G
W
K
Site 101
S1067
K
F
H
W
K
Q
R
S
S
D
T
F
R
R
R
Site 102
S1068
F
H
W
K
Q
R
S
S
D
T
F
R
R
R
R
Site 103
T1070
W
K
Q
R
S
S
D
T
F
R
R
R
R
W
R
Site 104
S1083
W
R
R
K
M
A
P
S
E
T
H
G
A
A
A
Site 105
T1102
E
G
A
L
G
A
D
T
T
E
D
G
D
E
K
Site 106
T1103
G
A
L
G
A
D
T
T
E
D
G
D
E
K
S
Site 107
S1110
T
E
D
G
D
E
K
S
L
E
K
Q
K
H
S
Site 108
Y1139
N
F
D
R
V
Y
I
Y
H
L
R
C
Y
V
Y
Site 109
Y1144
Y
I
Y
H
L
R
C
Y
V
Y
Q
A
R
N
L
Site 110
Y1146
Y
H
L
R
C
Y
V
Y
Q
A
R
N
L
L
A
Site 111
S1158
L
L
A
L
D
K
D
S
F
S
D
P
Y
A
H
Site 112
S1160
A
L
D
K
D
S
F
S
D
P
Y
A
H
I
C
Site 113
Y1163
K
D
S
F
S
D
P
Y
A
H
I
C
F
L
H
Site 114
T1174
C
F
L
H
R
S
K
T
T
E
I
I
H
S
T
Site 115
T1181
T
T
E
I
I
H
S
T
L
N
P
T
W
D
Q
Site 116
T1203
E
I
Y
G
E
P
Q
T
V
L
Q
N
P
P
K
Site 117
S1230
K
D
E
F
L
G
R
S
I
F
S
P
V
V
K
Site 118
S1240
S
P
V
V
K
L
N
S
E
M
D
I
T
P
K
Site 119
T1245
L
N
S
E
M
D
I
T
P
K
L
L
W
H
P
Site 120
S1277
I
L
R
G
K
D
G
S
N
L
P
I
L
P
P
Site 121
Y1291
P
Q
R
A
P
N
L
Y
M
V
P
Q
G
I
R
Site 122
S1340
C
G
G
E
R
V
E
S
V
V
I
K
N
L
K
Site 123
T1349
V
I
K
N
L
K
K
T
P
N
F
P
S
S
V
Site 124
S1354
K
K
T
P
N
F
P
S
S
V
L
F
M
K
V
Site 125
Y1369
F
L
P
K
E
E
L
Y
M
P
P
L
V
I
K
Site 126
Y1405
D
R
F
R
C
D
P
Y
A
G
K
E
D
I
V
Site 127
S1421
Q
L
K
A
S
L
L
S
A
P
P
C
R
D
I
Site 128
Y1458
V
D
W
W
S
K
F
Y
A
S
S
G
E
H
E
Site 129
S1460
W
S
K
F
Y
A
S
S
G
E
H
E
K
C
G
Site 130
Y1470
E
H
E
K
C
G
Q
Y
I
Q
K
G
Y
S
K
Site 131
Y1481
G
Y
S
K
L
K
I
Y
N
C
E
L
E
N
V
Site 132
S1498
F
E
G
L
T
D
F
S
D
T
F
K
L
Y
R
Site 133
T1500
G
L
T
D
F
S
D
T
F
K
L
Y
R
G
K
Site 134
Y1504
F
S
D
T
F
K
L
Y
R
G
K
S
D
E
N
Site 135
S1508
F
K
L
Y
R
G
K
S
D
E
N
E
D
P
S
Site 136
S1515
S
D
E
N
E
D
P
S
V
V
G
E
F
K
G
Site 137
Y1527
F
K
G
S
F
R
I
Y
P
L
P
D
D
P
S
Site 138
S1534
Y
P
L
P
D
D
P
S
V
P
A
P
P
R
Q
Site 139
S1548
Q
F
R
E
L
P
D
S
V
P
Q
E
C
T
V
Site 140
T1554
D
S
V
P
Q
E
C
T
V
R
I
Y
I
V
R
Site 141
Y1577
N
N
G
L
C
D
P
Y
I
K
I
T
L
G
K
Site 142
Y1593
V
I
E
D
R
D
H
Y
I
P
N
T
L
N
P
Site 143
T1597
R
D
H
Y
I
P
N
T
L
N
P
V
F
G
R
Site 144
Y1606
N
P
V
F
G
R
M
Y
E
L
S
C
Y
L
P
Site 145
Y1611
R
M
Y
E
L
S
C
Y
L
P
Q
E
K
D
L
Site 146
S1621
Q
E
K
D
L
K
I
S
V
Y
D
Y
D
T
F
Site 147
Y1623
K
D
L
K
I
S
V
Y
D
Y
D
T
F
T
R
Site 148
Y1625
L
K
I
S
V
Y
D
Y
D
T
F
T
R
D
E
Site 149
T1627
I
S
V
Y
D
Y
D
T
F
T
R
D
E
K
V
Site 150
S1647
D
L
E
N
R
F
L
S
R
F
G
S
H
C
G
Site 151
S1651
R
F
L
S
R
F
G
S
H
C
G
I
P
E
E
Site 152
Y1659
H
C
G
I
P
E
E
Y
C
V
S
G
V
N
T
Site 153
T1674
W
R
D
Q
L
R
P
T
Q
L
L
Q
N
V
A
Site 154
S1692
G
F
P
Q
P
I
L
S
E
D
G
S
R
I
R
Site 155
S1696
P
I
L
S
E
D
G
S
R
I
R
Y
G
G
R
Site 156
Y1700
E
D
G
S
R
I
R
Y
G
G
R
D
Y
S
L
Site 157
Y1705
I
R
Y
G
G
R
D
Y
S
L
D
E
F
E
A
Site 158
S1706
R
Y
G
G
R
D
Y
S
L
D
E
F
E
A
N
Site 159
T1744
L
V
P
E
H
V
E
T
R
T
L
H
S
T
F
Site 160
T1750
E
T
R
T
L
H
S
T
F
Q
P
N
I
S
Q
Site 161
S1770
W
V
D
V
F
P
K
S
L
G
P
P
G
P
P
Site 162
T1781
P
G
P
P
F
N
I
T
P
R
K
A
K
K
Y
Site 163
Y1788
T
P
R
K
A
K
K
Y
Y
L
R
V
I
I
W
Site 164
Y1789
P
R
K
A
K
K
Y
Y
L
R
V
I
I
W
N
Site 165
S1806
D
V
I
L
D
E
K
S
I
T
G
E
E
M
S
Site 166
T1808
I
L
D
E
K
S
I
T
G
E
E
M
S
D
I
Site 167
Y1816
G
E
E
M
S
D
I
Y
V
K
G
W
I
P
G
Site 168
Y1835
K
Q
K
T
D
V
H
Y
R
S
L
D
G
E
G
Site 169
S1837
K
T
D
V
H
Y
R
S
L
D
G
E
G
N
F
Site 170
Y1898
D
K
F
S
L
D
D
Y
L
G
F
L
E
L
D
Site 171
T1909
L
E
L
D
L
R
H
T
I
I
P
A
K
S
P
Site 172
S1915
H
T
I
I
P
A
K
S
P
E
K
C
R
L
D
Site 173
S1939
P
L
K
A
K
T
A
S
L
F
E
Q
K
S
M
Site 174
T2004
D
L
P
N
R
P
E
T
S
F
L
W
F
T
N
Site 175
S2005
L
P
N
R
P
E
T
S
F
L
W
F
T
N
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation