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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGL1
Full Name:
Ral guanine nucleotide dissociation stimulator-like 1
Alias:
RalGDS-like; RalGDS-like 1; RGL
Type:
Intracellular protein
Mass (Da):
86701
Number AA:
768
UniProt ID:
Q9NZL6
International Prot ID:
IPI00396431
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0008321
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051056
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
E
V
E
E
G
A
V
Y
H
V
T
L
K
R
V
Site 2
T28
E
G
A
V
Y
H
V
T
L
K
R
V
Q
I
Q
Site 3
S59
L
P
P
G
H
T
V
S
Q
Y
E
T
C
K
I
Site 4
Y61
P
G
H
T
V
S
Q
Y
E
T
C
K
I
R
T
Site 5
T63
H
T
V
S
Q
Y
E
T
C
K
I
R
T
I
K
Site 6
T83
K
L
V
E
N
L
L
T
A
F
G
D
N
D
F
Site 7
T106
T
Y
R
G
F
A
S
T
K
E
V
L
E
L
L
Site 8
Y117
L
E
L
L
L
D
R
Y
G
N
L
T
S
P
N
Site 9
T121
L
D
R
Y
G
N
L
T
S
P
N
C
E
E
D
Site 10
S122
D
R
Y
G
N
L
T
S
P
N
C
E
E
D
G
Site 11
S130
P
N
C
E
E
D
G
S
Q
S
S
S
E
S
K
Site 12
S132
C
E
E
D
G
S
Q
S
S
S
E
S
K
M
V
Site 13
S134
E
D
G
S
Q
S
S
S
E
S
K
M
V
I
R
Site 14
S136
G
S
Q
S
S
S
E
S
K
M
V
I
R
N
A
Site 15
T176
Q
K
L
L
D
Y
L
T
R
M
M
P
G
S
D
Site 16
S182
L
T
R
M
M
P
G
S
D
P
E
R
R
A
Q
Site 17
T209
T
D
N
G
L
P
N
T
I
S
F
S
L
E
E
Site 18
S211
N
G
L
P
N
T
I
S
F
S
L
E
E
E
E
Site 19
S213
L
P
N
T
I
S
F
S
L
E
E
E
E
E
L
Site 20
S225
E
E
L
E
G
G
E
S
A
E
F
T
C
F
S
Site 21
T229
G
G
E
S
A
E
F
T
C
F
S
E
D
L
V
Site 22
T275
E
N
K
H
L
A
P
T
I
R
A
T
I
S
Q
Site 23
S281
P
T
I
R
A
T
I
S
Q
F
N
T
L
T
K
Site 24
T302
L
G
G
K
E
L
K
T
Q
Q
R
A
K
I
I
Site 25
S339
V
S
A
L
Q
S
N
S
I
Y
R
L
K
K
T
Site 26
Y341
A
L
Q
S
N
S
I
Y
R
L
K
K
T
W
A
Site 27
T346
S
I
Y
R
L
K
K
T
W
A
A
V
P
R
D
Site 28
S362
M
L
M
F
E
E
L
S
D
I
F
S
D
H
N
Site 29
S366
E
E
L
S
D
I
F
S
D
H
N
N
H
L
T
Site 30
T373
S
D
H
N
N
H
L
T
S
R
E
L
L
M
K
Site 31
S391
S
K
F
A
N
L
D
S
S
V
K
E
N
Q
K
Site 32
S392
K
F
A
N
L
D
S
S
V
K
E
N
Q
K
R
Site 33
T400
V
K
E
N
Q
K
R
T
Q
R
R
L
Q
L
Q
Site 34
Y419
V
M
Q
G
T
V
P
Y
L
G
T
F
L
T
D
Site 35
T487
F
Q
R
Q
Q
L
L
T
E
E
E
S
Y
A
L
Site 36
S491
Q
L
L
T
E
E
E
S
Y
A
L
S
C
E
I
Site 37
Y492
L
L
T
E
E
E
S
Y
A
L
S
C
E
I
E
Site 38
S495
E
E
E
S
Y
A
L
S
C
E
I
E
A
A
A
Site 39
T506
E
A
A
A
D
A
S
T
T
S
P
K
P
R
K
Site 40
S508
A
A
D
A
S
T
T
S
P
K
P
R
K
S
M
Site 41
S514
T
S
P
K
P
R
K
S
M
V
K
R
L
S
L
Site 42
S520
K
S
M
V
K
R
L
S
L
L
F
L
G
S
D
Site 43
T530
F
L
G
S
D
M
I
T
S
P
T
P
T
K
E
Site 44
S531
L
G
S
D
M
I
T
S
P
T
P
T
K
E
Q
Site 45
T533
S
D
M
I
T
S
P
T
P
T
K
E
Q
P
K
Site 46
T535
M
I
T
S
P
T
P
T
K
E
Q
P
K
S
T
Site 47
S541
P
T
K
E
Q
P
K
S
T
A
S
G
S
S
G
Site 48
T542
T
K
E
Q
P
K
S
T
A
S
G
S
S
G
E
Site 49
S544
E
Q
P
K
S
T
A
S
G
S
S
G
E
S
M
Site 50
S546
P
K
S
T
A
S
G
S
S
G
E
S
M
D
S
Site 51
S550
A
S
G
S
S
G
E
S
M
D
S
V
S
V
S
Site 52
S553
S
S
G
E
S
M
D
S
V
S
V
S
S
C
E
Site 53
S555
G
E
S
M
D
S
V
S
V
S
S
C
E
S
N
Site 54
S557
S
M
D
S
V
S
V
S
S
C
E
S
N
H
S
Site 55
S558
M
D
S
V
S
V
S
S
C
E
S
N
H
S
E
Site 56
S561
V
S
V
S
S
C
E
S
N
H
S
E
A
E
E
Site 57
S564
S
S
C
E
S
N
H
S
E
A
E
E
G
S
I
Site 58
T572
E
A
E
E
G
S
I
T
P
M
D
T
P
D
E
Site 59
T576
G
S
I
T
P
M
D
T
P
D
E
P
Q
K
K
Site 60
S585
D
E
P
Q
K
K
L
S
E
S
S
S
S
C
S
Site 61
S587
P
Q
K
K
L
S
E
S
S
S
S
C
S
S
I
Site 62
S588
Q
K
K
L
S
E
S
S
S
S
C
S
S
I
H
Site 63
S589
K
K
L
S
E
S
S
S
S
C
S
S
I
H
S
Site 64
S590
K
L
S
E
S
S
S
S
C
S
S
I
H
S
M
Site 65
S592
S
E
S
S
S
S
C
S
S
I
H
S
M
D
T
Site 66
S593
E
S
S
S
S
C
S
S
I
H
S
M
D
T
N
Site 67
S596
S
S
C
S
S
I
H
S
M
D
T
N
S
S
G
Site 68
T599
S
S
I
H
S
M
D
T
N
S
S
G
M
S
S
Site 69
S601
I
H
S
M
D
T
N
S
S
G
M
S
S
L
I
Site 70
S602
H
S
M
D
T
N
S
S
G
M
S
S
L
I
N
Site 71
S605
D
T
N
S
S
G
M
S
S
L
I
N
P
L
S
Site 72
S606
T
N
S
S
G
M
S
S
L
I
N
P
L
S
S
Site 73
S612
S
S
L
I
N
P
L
S
S
P
P
S
C
N
N
Site 74
S613
S
L
I
N
P
L
S
S
P
P
S
C
N
N
N
Site 75
S616
N
P
L
S
S
P
P
S
C
N
N
N
P
K
I
Site 76
S627
N
P
K
I
H
K
R
S
V
S
V
T
S
I
T
Site 77
S629
K
I
H
K
R
S
V
S
V
T
S
I
T
S
T
Site 78
Y642
S
T
V
L
P
P
V
Y
N
Q
Q
N
E
D
T
Site 79
Y664
E
D
N
N
G
N
M
Y
K
S
I
M
L
T
S
Site 80
T670
M
Y
K
S
I
M
L
T
S
Q
D
K
T
P
A
Site 81
S671
Y
K
S
I
M
L
T
S
Q
D
K
T
P
A
V
Site 82
T675
M
L
T
S
Q
D
K
T
P
A
V
I
Q
R
A
Site 83
S690
M
L
K
H
N
L
D
S
D
P
A
E
E
Y
E
Site 84
Y696
D
S
D
P
A
E
E
Y
E
L
V
Q
V
I
S
Site 85
Y718
P
D
S
A
N
V
F
Y
A
M
N
S
Q
V
N
Site 86
S735
F
I
L
R
K
K
N
S
M
E
E
Q
V
K
L
Site 87
T746
Q
V
K
L
R
S
R
T
S
L
T
L
P
R
T
Site 88
S747
V
K
L
R
S
R
T
S
L
T
L
P
R
T
A
Site 89
T749
L
R
S
R
T
S
L
T
L
P
R
T
A
K
R
Site 90
T753
T
S
L
T
L
P
R
T
A
K
R
G
C
W
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation