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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COQ3
Full Name:
Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial
Alias:
3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; bA9819.1; coenzyme Q3 homolog, methyltransferase (yeast); coenzyme Q3, methyltransferase; DHHB methyltransferase; DHHB-MT; DHHB-MTase; dihydroxyhexaprenylbenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; methyltransferase COQ3
Type:
Methyltransferase; Cofactor and Vitamin Metabolism - ubiquinone and other terpenoid-quinone biosynthesis; EC 2.1.1.114
Mass (Da):
40998
Number AA:
369
UniProt ID:
Q9NZJ6
International Prot ID:
IPI00418414
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0008425
GO:0008171
GO:0004395
PhosphoSite+
KinaseNET
Biological Process:
GO:0006071
GO:0006744
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
W
S
G
R
K
L
G
S
S
G
G
W
F
L
R
Site 2
S10
S
G
R
K
L
G
S
S
G
G
W
F
L
R
V
Site 3
S43
V
Y
V
K
N
Q
L
S
G
T
L
Q
I
K
P
Site 4
T45
V
K
N
Q
L
S
G
T
L
Q
I
K
P
G
V
Site 5
S76
S
C
L
N
R
I
K
S
F
R
Y
P
W
A
R
Site 6
Y79
N
R
I
K
S
F
R
Y
P
W
A
R
L
Y
S
Site 7
Y85
R
Y
P
W
A
R
L
Y
S
T
S
Q
T
T
V
Site 8
S86
Y
P
W
A
R
L
Y
S
T
S
Q
T
T
V
D
Site 9
S88
W
A
R
L
Y
S
T
S
Q
T
T
V
D
S
G
Site 10
T90
R
L
Y
S
T
S
Q
T
T
V
D
S
G
E
V
Site 11
T135
I
R
D
N
L
L
K
T
I
P
N
H
Q
P
G
Site 12
T183
P
V
D
E
N
I
K
T
A
Q
C
H
K
S
F
Site 13
S189
K
T
A
Q
C
H
K
S
F
D
P
V
L
D
K
Site 14
Y200
V
L
D
K
R
I
E
Y
R
V
C
S
L
E
E
Site 15
S204
R
I
E
Y
R
V
C
S
L
E
E
I
V
E
E
Site 16
S286
H
T
W
E
K
F
V
S
P
E
T
L
E
S
I
Site 17
T289
E
K
F
V
S
P
E
T
L
E
S
I
L
E
S
Site 18
S292
V
S
P
E
T
L
E
S
I
L
E
S
N
G
L
Site 19
S296
T
L
E
S
I
L
E
S
N
G
L
S
V
Q
T
Site 20
S333
Y
A
A
H
A
V
K
S
R
V
Q
E
H
P
A
Site 21
S341
R
V
Q
E
H
P
A
S
A
E
F
V
L
K
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation