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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GTSE1
Full Name:
G2 and S phase-expressed protein 1
Alias:
B99; B99 homologue; B99 protein; G2 and S phase expressed protein 1; G-2 and S-phase expressed 1; GTSE; Gtse-1
Type:
Cell cycle regulation; Apoptosis
Mass (Da):
76615
Number AA:
720
UniProt ID:
Q9NYZ3
International Prot ID:
IPI00160901
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
GO:0005881
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0000085
GO:0006950
GO:0006974
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
E
K
F
D
F
D
L
S
L
S
S
S
S
A
N
Site 2
S24
F
D
F
D
L
S
L
S
S
S
S
A
N
E
D
Site 3
S26
F
D
L
S
L
S
S
S
S
A
N
E
D
D
E
Site 4
S49
K
E
R
C
I
A
A
S
L
E
L
N
N
P
V
Site 5
S65
E
Q
P
P
L
P
T
S
E
S
P
F
A
W
S
Site 6
S67
P
P
L
P
T
S
E
S
P
F
A
W
S
P
L
Site 7
S72
S
E
S
P
F
A
W
S
P
L
A
G
E
K
F
Site 8
Y83
G
E
K
F
V
E
V
Y
K
E
A
H
L
L
A
Site 9
S96
L
A
L
H
I
E
S
S
S
R
N
Q
A
A
Q
Site 10
S112
A
K
P
E
D
P
R
S
Q
G
V
E
R
F
I
Site 11
S122
V
E
R
F
I
Q
E
S
K
L
K
I
N
L
F
Site 12
S138
K
E
K
E
M
K
K
S
P
T
S
L
K
R
E
Site 13
T140
K
E
M
K
K
S
P
T
S
L
K
R
E
T
Y
Site 14
S141
E
M
K
K
S
P
T
S
L
K
R
E
T
Y
Y
Site 15
T146
P
T
S
L
K
R
E
T
Y
Y
L
S
D
S
P
Site 16
Y147
T
S
L
K
R
E
T
Y
Y
L
S
D
S
P
L
Site 17
Y148
S
L
K
R
E
T
Y
Y
L
S
D
S
P
L
L
Site 18
S150
K
R
E
T
Y
Y
L
S
D
S
P
L
L
G
P
Site 19
S152
E
T
Y
Y
L
S
D
S
P
L
L
G
P
P
V
Site 20
S167
G
E
P
R
L
L
A
S
S
P
A
L
P
S
S
Site 21
S168
E
P
R
L
L
A
S
S
P
A
L
P
S
S
G
Site 22
S173
A
S
S
P
A
L
P
S
S
G
A
Q
A
R
L
Site 23
S174
S
S
P
A
L
P
S
S
G
A
Q
A
R
L
T
Site 24
T181
S
G
A
Q
A
R
L
T
R
A
P
G
P
P
H
Site 25
S189
R
A
P
G
P
P
H
S
A
H
A
L
P
R
E
Site 26
S197
A
H
A
L
P
R
E
S
C
T
A
H
A
A
S
Site 27
S204
S
C
T
A
H
A
A
S
Q
A
A
T
Q
R
K
Site 28
T208
H
A
A
S
Q
A
A
T
Q
R
K
P
G
T
K
Site 29
S223
L
L
L
P
R
A
A
S
V
R
G
R
S
I
P
Site 30
S228
A
A
S
V
R
G
R
S
I
P
G
A
A
E
K
Site 31
S243
P
K
K
E
I
P
A
S
P
S
R
T
K
I
P
Site 32
S245
K
E
I
P
A
S
P
S
R
T
K
I
P
A
E
Site 33
T247
I
P
A
S
P
S
R
T
K
I
P
A
E
K
E
Site 34
S255
K
I
P
A
E
K
E
S
H
R
D
V
L
P
D
Site 35
S276
V
N
V
P
A
A
G
S
H
L
G
Q
G
K
R
Site 36
T296
N
K
L
G
L
K
K
T
L
L
K
A
P
G
S
Site 37
S303
T
L
L
K
A
P
G
S
T
S
N
L
A
R
K
Site 38
T304
L
L
K
A
P
G
S
T
S
N
L
A
R
K
S
Site 39
S311
T
S
N
L
A
R
K
S
S
S
G
P
V
W
S
Site 40
S312
S
N
L
A
R
K
S
S
S
G
P
V
W
S
G
Site 41
S313
N
L
A
R
K
S
S
S
G
P
V
W
S
G
A
Site 42
S318
S
S
S
G
P
V
W
S
G
A
S
S
A
C
T
Site 43
S321
G
P
V
W
S
G
A
S
S
A
C
T
S
P
A
Site 44
T325
S
G
A
S
S
A
C
T
S
P
A
V
G
K
A
Site 45
S326
G
A
S
S
A
C
T
S
P
A
V
G
K
A
K
Site 46
S334
P
A
V
G
K
A
K
S
S
E
F
A
S
I
P
Site 47
S335
A
V
G
K
A
K
S
S
E
F
A
S
I
P
A
Site 48
S339
A
K
S
S
E
F
A
S
I
P
A
N
S
S
R
Site 49
S344
F
A
S
I
P
A
N
S
S
R
P
L
S
N
I
Site 50
S345
A
S
I
P
A
N
S
S
R
P
L
S
N
I
S
Site 51
S349
A
N
S
S
R
P
L
S
N
I
S
K
S
G
R
Site 52
S352
S
R
P
L
S
N
I
S
K
S
G
R
M
G
P
Site 53
S354
P
L
S
N
I
S
K
S
G
R
M
G
P
A
M
Site 54
T392
E
L
A
A
E
Q
L
T
A
P
P
S
A
S
P
Site 55
S396
E
Q
L
T
A
P
P
S
A
S
P
T
Q
P
Q
Site 56
S398
L
T
A
P
P
S
A
S
P
T
Q
P
Q
T
P
Site 57
T400
A
P
P
S
A
S
P
T
Q
P
Q
T
P
E
G
Site 58
T404
A
S
P
T
Q
P
Q
T
P
E
G
G
G
Q
W
Site 59
S414
G
G
G
Q
W
L
N
S
S
C
A
W
S
E
S
Site 60
S415
G
G
Q
W
L
N
S
S
C
A
W
S
E
S
S
Site 61
S419
L
N
S
S
C
A
W
S
E
S
S
Q
L
N
K
Site 62
S422
S
C
A
W
S
E
S
S
Q
L
N
K
T
R
S
Site 63
T427
E
S
S
Q
L
N
K
T
R
S
I
R
R
R
D
Site 64
S429
S
Q
L
N
K
T
R
S
I
R
R
R
D
S
C
Site 65
S435
R
S
I
R
R
R
D
S
C
L
N
S
K
T
K
Site 66
S439
R
R
D
S
C
L
N
S
K
T
K
V
M
P
T
Site 67
T446
S
K
T
K
V
M
P
T
P
T
N
Q
F
K
I
Site 68
S457
Q
F
K
I
P
K
F
S
I
G
D
S
P
D
S
Site 69
S461
P
K
F
S
I
G
D
S
P
D
S
S
T
P
K
Site 70
S464
S
I
G
D
S
P
D
S
S
T
P
K
L
S
R
Site 71
S465
I
G
D
S
P
D
S
S
T
P
K
L
S
R
A
Site 72
T466
G
D
S
P
D
S
S
T
P
K
L
S
R
A
Q
Site 73
S470
D
S
S
T
P
K
L
S
R
A
Q
R
P
Q
S
Site 74
S477
S
R
A
Q
R
P
Q
S
C
T
S
V
G
R
V
Site 75
T479
A
Q
R
P
Q
S
C
T
S
V
G
R
V
T
V
Site 76
S480
Q
R
P
Q
S
C
T
S
V
G
R
V
T
V
H
Site 77
T485
C
T
S
V
G
R
V
T
V
H
S
T
P
V
R
Site 78
S488
V
G
R
V
T
V
H
S
T
P
V
R
R
S
S
Site 79
T489
G
R
V
T
V
H
S
T
P
V
R
R
S
S
G
Site 80
S494
H
S
T
P
V
R
R
S
S
G
P
A
P
Q
S
Site 81
S495
S
T
P
V
R
R
S
S
G
P
A
P
Q
S
L
Site 82
S501
S
S
G
P
A
P
Q
S
L
L
S
A
R
R
V
Site 83
S504
P
A
P
Q
S
L
L
S
A
R
R
V
S
A
L
Site 84
S509
L
L
S
A
R
R
V
S
A
L
P
T
P
A
S
Site 85
T513
R
R
V
S
A
L
P
T
P
A
S
R
R
C
S
Site 86
S516
S
A
L
P
T
P
A
S
R
R
C
S
G
L
P
Site 87
S520
T
P
A
S
R
R
C
S
G
L
P
P
M
T
P
Site 88
T526
C
S
G
L
P
P
M
T
P
K
T
M
P
R
A
Site 89
T529
L
P
P
M
T
P
K
T
M
P
R
A
V
G
S
Site 90
S536
T
M
P
R
A
V
G
S
P
L
C
V
P
A
R
Site 91
S546
C
V
P
A
R
R
R
S
S
E
P
R
K
N
S
Site 92
S547
V
P
A
R
R
R
S
S
E
P
R
K
N
S
A
Site 93
S553
S
S
E
P
R
K
N
S
A
M
R
T
E
P
T
Site 94
T557
R
K
N
S
A
M
R
T
E
P
T
R
E
S
N
Site 95
S563
R
T
E
P
T
R
E
S
N
R
K
T
D
S
R
Site 96
T567
T
R
E
S
N
R
K
T
D
S
R
L
V
D
V
Site 97
S569
E
S
N
R
K
T
D
S
R
L
V
D
V
S
P
Site 98
S575
D
S
R
L
V
D
V
S
P
D
R
G
S
P
P
Site 99
S580
D
V
S
P
D
R
G
S
P
P
S
R
V
P
Q
Site 100
S583
P
D
R
G
S
P
P
S
R
V
P
Q
A
L
N
Site 101
S592
V
P
Q
A
L
N
F
S
P
E
E
S
D
S
T
Site 102
S596
L
N
F
S
P
E
E
S
D
S
T
F
S
K
S
Site 103
S598
F
S
P
E
E
S
D
S
T
F
S
K
S
T
A
Site 104
T599
S
P
E
E
S
D
S
T
F
S
K
S
T
A
T
Site 105
S603
S
D
S
T
F
S
K
S
T
A
T
E
V
A
R
Site 106
T637
K
L
E
P
L
A
V
T
P
D
A
A
S
Q
P
Site 107
S665
E
A
H
V
A
V
G
S
E
S
R
P
L
I
D
Site 108
T675
R
P
L
I
D
L
M
T
N
T
P
D
M
N
K
Site 109
T677
L
I
D
L
M
T
N
T
P
D
M
N
K
N
V
Site 110
S688
N
K
N
V
A
K
P
S
P
V
V
G
Q
L
I
Site 111
S698
V
G
Q
L
I
D
L
S
S
P
L
I
Q
L
S
Site 112
S699
G
Q
L
I
D
L
S
S
P
L
I
Q
L
S
P
Site 113
S705
S
S
P
L
I
Q
L
S
P
E
A
D
K
E
N
Site 114
S715
A
D
K
E
N
V
D
S
P
L
L
K
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation