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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF226
Full Name:
Zinc finger protein 226
Alias:
Kruppel-associated box; Zinc finger 226; ZN226
Type:
Mass (Da):
91920
Number AA:
UniProt ID:
Q9NYT6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
G
P
A
Q
R
K
L
Y
R
D
V
M
V
E
N
Site 2
S46
E
N
F
R
N
L
L
S
V
G
H
P
P
F
K
Site 3
S57
P
P
F
K
Q
D
V
S
P
I
E
R
N
E
Q
Site 4
T72
L
W
I
M
T
T
A
T
R
R
Q
G
N
L
G
Site 5
S84
N
L
G
E
K
N
Q
S
K
L
I
T
V
Q
D
Site 6
T88
K
N
Q
S
K
L
I
T
V
Q
D
R
E
S
E
Site 7
S94
I
T
V
Q
D
R
E
S
E
E
E
L
S
C
W
Site 8
Y132
H
K
Q
G
D
F
P
Y
Q
V
G
T
E
L
S
Site 9
S143
T
E
L
S
I
Q
I
S
E
D
E
N
Y
I
V
Site 10
Y148
Q
I
S
E
D
E
N
Y
I
V
N
K
A
D
G
Site 11
T159
K
A
D
G
P
N
N
T
G
N
P
E
F
P
I
Site 12
S172
P
I
L
R
T
Q
D
S
W
R
K
T
F
L
T
Site 13
T176
T
Q
D
S
W
R
K
T
F
L
T
E
S
Q
R
Site 14
T179
S
W
R
K
T
F
L
T
E
S
Q
R
L
N
R
Site 15
S181
R
K
T
F
L
T
E
S
Q
R
L
N
R
D
Q
Site 16
S191
L
N
R
D
Q
Q
I
S
I
K
N
K
L
C
Q
Site 17
S220
D
G
H
R
V
H
K
S
E
K
S
Y
R
P
N
Site 18
S223
R
V
H
K
S
E
K
S
Y
R
P
N
D
Y
E
Site 19
Y224
V
H
K
S
E
K
S
Y
R
P
N
D
Y
E
K
Site 20
Y229
K
S
Y
R
P
N
D
Y
E
K
D
N
M
K
I
Site 21
T247
D
H
N
S
M
I
H
T
G
Q
K
S
Y
Q
C
Site 22
S262
N
E
C
K
K
P
F
S
D
L
S
S
F
D
L
Site 23
S265
K
K
P
F
S
D
L
S
S
F
D
L
H
Q
Q
Site 24
S266
K
P
F
S
D
L
S
S
F
D
L
H
Q
Q
L
Site 25
S275
D
L
H
Q
Q
L
Q
S
G
E
K
S
L
T
C
Site 26
S279
Q
L
Q
S
G
E
K
S
L
T
C
V
E
R
G
Site 27
T281
Q
S
G
E
K
S
L
T
C
V
E
R
G
K
G
Site 28
Y291
E
R
G
K
G
F
C
Y
S
P
V
L
P
V
H
Site 29
S292
R
G
K
G
F
C
Y
S
P
V
L
P
V
H
Q
Site 30
S317
D
E
C
G
K
E
F
S
Q
G
A
H
L
Q
T
Site 31
Y335
V
H
V
I
E
K
P
Y
K
C
K
Q
C
G
K
Site 32
S345
K
Q
C
G
K
G
F
S
R
R
S
A
L
N
V
Site 33
S348
G
K
G
F
S
R
R
S
A
L
N
V
H
C
K
Site 34
S373
E
E
C
G
R
A
F
S
Q
A
S
H
L
Q
D
Site 35
T386
Q
D
H
Q
R
L
H
T
G
E
K
P
F
K
C
Site 36
S399
K
C
D
A
C
G
K
S
F
S
R
N
S
H
L
Site 37
S401
D
A
C
G
K
S
F
S
R
N
S
H
L
Q
S
Site 38
S404
G
K
S
F
S
R
N
S
H
L
Q
S
H
Q
R
Site 39
S408
S
R
N
S
H
L
Q
S
H
Q
R
V
H
T
G
Site 40
T414
Q
S
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 41
Y435
F
I
C
S
S
N
L
Y
I
H
Q
R
V
H
T
Site 42
T442
Y
I
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 43
S457
E
E
C
G
K
G
F
S
R
P
S
S
L
Q
A
Site 44
S460
G
K
G
F
S
R
P
S
S
L
Q
A
H
Q
G
Site 45
S461
K
G
F
S
R
P
S
S
L
Q
A
H
Q
G
V
Site 46
T470
Q
A
H
Q
G
V
H
T
G
E
K
S
Y
I
C
Site 47
Y475
V
H
T
G
E
K
S
Y
I
C
T
V
C
G
K
Site 48
T478
G
E
K
S
Y
I
C
T
V
C
G
K
G
F
T
Site 49
S487
C
G
K
G
F
T
L
S
S
N
L
Q
A
H
Q
Site 50
S488
G
K
G
F
T
L
S
S
N
L
Q
A
H
Q
R
Site 51
T498
Q
A
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 52
Y503
V
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 53
S516
G
K
S
F
R
R
N
S
H
Y
Q
V
H
L
V
Site 54
Y518
S
F
R
R
N
S
H
Y
Q
V
H
L
V
V
H
Site 55
T526
Q
V
H
L
V
V
H
T
G
E
K
P
Y
K
C
Site 56
S541
E
I
C
G
K
G
F
S
Q
S
S
Y
L
Q
I
Site 57
S543
C
G
K
G
F
S
Q
S
S
Y
L
Q
I
H
Q
Site 58
S544
G
K
G
F
S
Q
S
S
Y
L
Q
I
H
Q
K
Site 59
Y545
K
G
F
S
Q
S
S
Y
L
Q
I
H
Q
K
A
Site 60
T582
Q
I
H
Q
L
I
H
T
G
E
K
P
Y
K
C
Site 61
S597
E
E
C
G
K
G
F
S
R
R
A
D
L
K
I
Site 62
T610
K
I
H
C
R
I
H
T
G
E
K
P
Y
N
C
Site 63
Y615
I
H
T
G
E
K
P
Y
N
C
E
E
C
G
K
Site 64
S628
G
K
V
F
R
Q
A
S
N
L
L
A
H
Q
R
Site 65
S638
L
A
H
Q
R
V
H
S
G
E
K
P
F
K
C
Site 66
S651
K
C
E
E
C
G
K
S
F
G
R
S
A
H
L
Site 67
S655
C
G
K
S
F
G
R
S
A
H
L
Q
A
H
Q
Site 68
Y671
V
H
T
G
D
K
P
Y
K
C
D
E
C
G
K
Site 69
T694
D
M
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 70
Y699
V
H
T
G
E
K
P
Y
K
C
G
E
C
G
K
Site 71
Y707
K
C
G
E
C
G
K
Y
F
S
Q
A
S
S
L
Site 72
S709
G
E
C
G
K
Y
F
S
Q
A
S
S
L
Q
L
Site 73
S713
K
Y
F
S
Q
A
S
S
L
Q
L
H
Q
S
V
Site 74
S719
S
S
L
Q
L
H
Q
S
V
H
T
G
E
K
P
Site 75
T722
Q
L
H
Q
S
V
H
T
G
E
K
P
Y
K
C
Site 76
Y727
V
H
T
G
E
K
P
Y
K
C
D
V
C
G
K
Site 77
S737
D
V
C
G
K
V
F
S
R
S
S
Q
L
Q
S
Site 78
S739
C
G
K
V
F
S
R
S
S
Q
L
Q
S
H
Q
Site 79
S740
G
K
V
F
S
R
S
S
Q
L
Q
S
H
Q
R
Site 80
S744
S
R
S
S
Q
L
Q
S
H
Q
R
V
H
T
G
Site 81
S765
E
I
C
G
K
S
F
S
W
R
S
N
L
T
V
Site 82
S768
G
K
S
F
S
W
R
S
N
L
T
V
H
H
R
Site 83
S782
R
I
H
V
G
D
K
S
Y
K
S
N
R
G
G
Site 84
Y783
I
H
V
G
D
K
S
Y
K
S
N
R
G
G
K
Site 85
S785
V
G
D
K
S
Y
K
S
N
R
G
G
K
N
I
Site 86
S795
G
G
K
N
I
R
E
S
T
Q
E
K
K
S
I
Site 87
T796
G
K
N
I
R
E
S
T
Q
E
K
K
S
I
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation